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Clobetasol Topical

Generic Name: clobetasol topical (kloe BAY ta sol)
Brand Name: Clobex, Clodan, Impoyz, Olux, Olux-E, Temovate, Tovet, ...show all 17 brand names

Medically reviewed by Philip Thornton, DipPharm. Last updated on Sep 23, 2020.

What is clobetasol topical?

Clobetasol is a highly potent corticosteroid that helps reduce inflammation in the body.

Clobetasol topical (for the skin) is used to treat inflammation and itching caused by plaque psoriasis and skin conditions that respond to corticosteroid medication.

Clobetasol topical is available in a cream, gel, ointment, lotion, solution, foam or spray.

Important Information

Do not use clobetasol topical to treat acne, rosacea, or a rash around the mouth.

Use care when putting on a large part of the skin or where there are open wounds. Talk with the doctor.<./p>

Clobetasol may cause harm if swallowed. If swallowed, call a doctor or poison control center right away.

Clobetasol may raise the chance of cataracts or glaucoma. Talk with your doctor.

Clobetasol may affect growth in children and teens in some cases. They may need regular growth checks.

If you are breast-feeding, do not apply clobetasol cream, gel, ointment, lotion, solution, foam or spray to the nipple or the area around it.

Before taking this medicine

You should not use clobetasol topical if you are allergic to it.

To make sure clobetasol is safe for you, tell your doctor if you have ever had:

Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

It is not known whether clobetasol topical will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply clobetasol to your chest, avoid areas that may come into contact with the baby's mouth.

Clobetasol is not approved for use by anyone younger than 12 years old. Some brands or forms of this medicine are for use only in adults 18 and over.

Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.

How should I use clobetasol?

Use clobetasol exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Do not take by mouth. Topical medicine is for use only on the skin. Rinse with water if this medicine gets in your eyes or mouth.

Do not use clobetasol on broken or infected skin. Also avoid using this medicine in open wounds.

Wash your hands before and after using clobetasol, unless you are using the medicine to treat the skin on your hands.

Apply a thin layer of medicine to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to.

Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.

If you are treating the diaper area, do not use plastic pants or tight-fitting diapers.

This medicine is for short-term use only (2 weeks, or up to 4 weeks for scalp psoriasis). Follow your doctor's dosing instructions very carefully.

If you use clobetasol to treat plaque psoriasis, you should stop using the medicine once your skin symptoms are controlled.

Call your doctor if your symptoms do not improve, or if they get worse.

You should not stop using clobetasol suddenly. Follow your doctor's instructions about tapering your dose.

Store at room temperature away from moisture and heat. Keep from freezing.

Clobetasol foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin.

What happens if I miss a dose?

Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

High doses or long-term use of clobetasol can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using clobetasol?

Avoid applying clobetasol topical to your face, underarms, or groin area.

Do not use this medicine to treat any condition that has not been checked by your doctor.

Avoid using other topical steroid medications on the areas you treat with clobetasol unless your doctor tells you to.

Clobetasol side effects

Get emergency medical help if you have signs of an allergic reaction to clobetasol: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • worsening of your skin condition;

  • redness, warmth, swelling, oozing, or severe irritation of any treated skin;

  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;

  • high blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor; or

  • possible signs of absorbing this medicine through your skin - weight gain in your face and shoulders, slow wound healing, skin discoloration, thinning skin, increased body hair, tiredness, mood changes, menstrual changes, sexual changes.

Common clobetasol side effects may include:

  • burning, itching, swelling, or irritation of treated skin;

  • dry or cracking skin;

  • redness or crusting around your hair follicles;

  • spider veins;

  • stretch marks, thinning skin;

  • rash or hives;

  • acne; or

  • temporary hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect clobetasol?

Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use clobetasol topical only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Popular FAQ

Clobetasol is effective at stimulating hair growth. Research has shown hair regrowth was stimulated in about 20 to 25% of people who used clobetasol ointment and in about 47% of people who used clobetasol foam. Regrowth was noticed as early as six weeks into treatment but may take up to 12 to 14 weeks to develop. Continue reading

It takes about one to three days for clobetasol propionate to start working when it is being used to treat eczema. Some improvement in symptoms such as inflammation (redness) and itching, should be noticed within this time. Other symptoms, such as dryness, crusting, or scaling may take a bit longer to resolve, but improvement should occur within a week. Continue reading

Olux and Olux-E are both topical corticosteroid foams that contain clobetasol propionate 0.05%, but they are approved for somewhat different uses. Olux is used to treat plaque psoriasis of the scalp and other areas on the body (except the face and skin areas that rub together). Olux-E, an emulsion formulation, is approved to treat skin conditions that respond to topical corticosteroids (for example: psoriasis, seborrheic dermatitis, and eczema). Continue reading

Clobex Spray 0.05% and Clobex Lotion 0.05% are both applied to the affected skin area twice a day and rubbed in gently. Do not use longer than 2 weeks unless directed by your doctor. Clobex Shampoo 0.05% is applied as a thin film to the affected scalp area once per day. Apply only to dry scalp (not wet). Leave in place for 15 minutes before lathering and rinsing. If your scalp psoriasis does not improve in 4 weeks, contact your doctor. Continue reading

Yes, hair thinning and hair loss has been reported as a side effect with the use of clobetasol propionate topical 0.05% (Olux Foam). The number of people that have reported these side effects is not known. This does not appear to be a frequent or serious side effect. Continue reading

The Olux Foam product is specifically approved and formulated to be used for plaque psoriasis on the scalp. To use Olux, move your hair away and apply a thin layer of the foam to the affected scalp area 2 times each day and rub in gently. Wash your hands after each use. Do not bandage or cover the area unless your doctor directs you to do this. Continue reading

Clobex (clobetasol propionate) Spray 0.05% is used to treat psoriasis on the skin and Clobex Shampoo 0.05% is approved to treat scalp psoriasis. Clobex Lotion 0.05% is also approved to treat psoriasis, in addition to other skin conditions such as eczema. Lotions and sprays are often more acceptable for use on the skin or hard-to-reach areas, while shampoos work well on the scalp. Continue reading

Halobetasol and clobetasol are both classified as super high-potency or high-potency topical corticosteroid (“steroid”) creams used on the skin. They are both FDA-approved to treat plaque psoriasis and skin conditions that are responsive to topical corticosteroids, such as dermatitis and eczema (atopic dermatitis). They lessen skin redness and pain, itching, dryness and scaling. Continue reading

Clodan (clobetasol propionate) Shampoo, 0.05% is applied onto a dry scalp once a day as a thin film. Use only in adults 18 years and older. Do not apply to a wet scalp and only apply to the area being treated. Continue reading

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