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Tremfya Side Effects

Generic Name: guselkumab

Note: This document contains side effect information about guselkumab. Some of the dosage forms listed on this page may not apply to the brand name Tremfya.

For the Consumer

Applies to guselkumab: subcutaneous solution prefilled syringe

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
  • Red, painful, or itchy skin that is hot to touch.
  • Shortness of breath.
  • Cough with or without phlegm or blood.
  • Weight loss.
  • Passing urine more often.
  • Loose stools (diarrhea).
  • Stomach pain.
  • Sweating a lot.
  • Muscle pain.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Signs of a common cold.
  • Headache.
  • Irritation where the shot is given.
  • Joint pain.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to guselkumab: subcutaneous solution

Immunologic

Very common (10% or more): Infections (23%)
Common (1% to 10%): Tinea infections, herpes simplex infections, immunogenicity[Ref]

Local

Common (1% to 10%): Injection site reactions (e.g., injection site erythema, bruising, hematoma, hemorrhage, swelling, edema, pruritus, pain, discoloration, induration, inflammation, urticaria)[Ref]

Musculoskeletal

Common (1% to 10%): Arthralgia[Ref]

Hepatic

Common (1% to 10%): Elevated liver enzymes[Ref]

Respiratory

Very common (10% or more): Respiratory tract infection (e.g., nasopharyngitis, upper respiratory tract infection, pharyngitis, viral upper respiratory tract infection) (14%)[Ref]

Nervous system

Common (1% to 10%): Headache[Ref]

Gastrointestinal

Common (1% to 10%): Diarrhea, gastroenteritis (including viral gastroenteritis)[Ref]

References

1. "Product Information. Tremfya (guselkumab)." Janssen Biotech, Inc., Horsham, PA, PA.

Some side effects of Tremfya may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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