Tremfya Side Effects
Generic name: guselkumab
Note: This document contains side effect information about guselkumab. Some dosage forms listed on this page may not apply to the brand name Tremfya.
Applies to guselkumab: subcutaneous solution.
Serious side effects of Tremfya
Along with its needed effects, guselkumab (the active ingredient contained in Tremfya) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking guselkumab:
More common
- Body aches or pain
- chills
- cough
- difficulty in breathing
- ear congestion
- fever
- headache
- loss of voice
- nasal congestion
- runny nose
- sneezing
- sore throat
- unusual tiredness or weakness
Less Common
- Burning or stinging of the skin
- diarrhea
- itching in the genital or other skin areas
- loss of appetite
- nausea
- painful cold sores or blisters on the lips, nose, eyes, or genitals
- scaling
- stomach pain
Rare
- Headache, severe and throbbing
- hives or welts, itching, skin rash
- white patches in the mouth or throat or on the tongue
Other side effects of Tremfya
Some side effects of guselkumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
- difficulty in moving
- muscle pain or stiffness
- pain in the joints
Rare
- Redness of the skin
For Healthcare Professionals
Applies to guselkumab: subcutaneous solution.
Immunologic
Very common (10% or more): Infections (23%)
Common (1% to 10%): Tinea infections, herpes simplex infections, immunogenicity[Ref]
Local
Common (1% to 10%): Injection site reactions (e.g., injection site erythema, bruising, hematoma, hemorrhage, swelling, edema, pruritus, pain, discoloration, induration, inflammation, urticaria)[Ref]
Musculoskeletal
Common (1% to 10%): Arthralgia[Ref]
Hepatic
Common (1% to 10%): Elevated liver enzymes[Ref]
Respiratory
Very common (10% or more): Respiratory tract infection (e.g., nasopharyngitis, upper respiratory tract infection, pharyngitis, viral upper respiratory tract infection) (14%)[Ref]
Nervous system
Common (1% to 10%): Headache[Ref]
Gastrointestinal
Common (1% to 10%): Diarrhea, gastroenteritis (including viral gastroenteritis)[Ref]
Hypersensitivity
Uncommon (0.1% to 1%): Hypersensitivity
Frequency not reported: Anaphylaxis[Ref]
Dermatologic
Common (1% to 10%): Urticaria, rash[Ref]
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References
1. Product Information. Tremfya (guselkumab). Janssen Biotech, Inc. 2017.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.