Tremfya Alternatives Compared
| Tremfya | Otezla | Cosentyx |
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| Tremfya (guselkumab) | Otezla (apremilast) | Cosentyx (secukinumab) |
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Prescription only
Tremfya is an interleukin inhibitor that may be used to treat plaque psoriasis or psoriatic arthritis in adults. People receiving Tremfya can be taught how to self-administer it every eight weeks by... View more |
Prescription only
Otezla is a PDE4 inhibitor that may be used to treat plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet’s Disease. It has been associated with severe diarrhea, nausea, and v... View more |
Prescription only
Cosentyx may be used to treat plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and some other conditions. After an initial loading dose, Cosentyx needs to be injected subcutaneously... View more |
Related suggestions Plaque Psoriasis
Psoriatic Arthritis
Popular comparisons
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| More about Tremfya (guselkumab) | More about Otezla (apremilast) | More about Cosentyx (secukinumab) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
No lower-cost generic available |
No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Tremfya has an average rating of 6.7 out of 10 from a total of 69 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 29% reported a negative effect. |
Otezla has an average rating of 5.0 out of 10 from a total of 423 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 42% reported a negative effect. |
Cosentyx has an average rating of 6.1 out of 10 from a total of 232 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 34% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See also: Tremfya side effects in more detail. |
Common side effects include:
See also: Otezla side effects in more detail. |
Common side effects include:
See also: Cosentyx side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Tremfya prices |
View all Otezla prices |
View all Cosentyx prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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432 hours |
9 hours |
744 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 211 drugs are known to interact with Tremfya:
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A total of 87 drugs are known to interact with Otezla:
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A total of 210 drugs are known to interact with Cosentyx:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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July 13, 2017 |
March 21, 2014 |
January 21, 2015 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.