Cosentyx and Fatigue: What Users Say

• Bet...
• Taken for 1 to 6 months
• May 28, 2020

For Plaque Psoriasis "So, I previously left a review for Stelara - which I had stopped and then had a full-blown inflammatory response in my body, joints, tendons, spine, and scalp psoriasis. I since started Cosentyx. I have done the five loading doses (300 mg - 2 injections), and I honestly feel 10x better. I felt so debilitated in the previous state. (I'm in my 30s and very active, so debility should not be in my vocab). I still have a little residual arthritis in my hips and tendons, but I think it will clear after a while. *Fingers crossed*. It's supposed to take anywhere between 12-16 weeks to fully take effect, so I have got time to be patient. If not, a little Tylenol and Aleve daily have been working well. I do not feel fatigued as I did with Stelara. I do get a random nasal drip, but it's manageable compared to the alternative. So I feel like I'm getting back to normal. I probably have to take a biologic for the rest of my life to function normally, but if it works, I'm happy. I will update as time goes on."

• Anonymous
• Taken for 6 months to 1 year
• January 7, 2021

For Ankylosing Spondylitis "I started with Humira, had that for 3 years, then out of the blue, it stopped working. Was then on Benepali and got an allergic reaction to it (eczema under my feet and on my hands, etc.). Was on no drugs whatsoever for 4 months after that (and had the worst pain ever, even worse than how it was before I started with Humira). Then I started with Cosentyx, and it has so far - knock on wood - worked great. I am absolutely pain-free and have more or less no side effects. 'More or less side effects'... I have had the same side effects of all of these drugs (except the allergy). I am fatigued, and every now and then I have some bowel problems and headaches. But I can live with that because I am nevertheless feeling better than with no treatment, and even the fatigue I get from the disease is worse than the fatigue from the treatment. This disease will never go away, and I'm just happy that there are some treatments that actually work."

• Sco...
• March 3, 2021

For Ankylosing Spondylitis "Diagnosed with AS 11-20. Earlier in the year, I fractured my S/I joint from sports. Over 9 months, docs treating me for fractured S/I joint. MRIs continued to show growing edema up the spine. Was on crutches for 6 months. Referred to rheum doctor and was told I have AS. After the AS diagnosis, 5 weeks of loading dose (300). After that, I went to once a month, still 300. I felt I had immediate positive results, big changes quickly. No need for the crutches. On monthly doses for 3 months. The quick positive changes have slowed down, but I still feel better than in 2020. Occasional fatigue, but I credit that to lack of activity for over a year. I went from playing competitive sports three nights a week to nothing, so I was out of shape. I’ve had none of the side effects I’ve read on these reviews except some fatigue. I’m willing to continue treatment. Had I read these reviews prior to starting treatment, I may have declined. I’m off crutches, and I’m feeling better than I did. I’m in my 50s."

• Kel...
• Taken for 1 to 6 months
• June 24, 2019

For Psoriatic Arthritis "I have had vertigo symptoms, extreme joint pain, fatigue, as a result of all medications that supposedly treat psoriatic arthritis and ankylosing spondylitis. So far, every medication I’ve tried has made me much worse. Humira attacked my heart and almost killed me. The steroids caused panic attacks, shortness of breath, and high blood pressure. That’s just to name a few! I think these medications are poison to anyone’s system. I have decided to avoid medications altogether. I still have pain, but at least I don’t have ten to twenty other awful side effects to go with it. Not to mention, none of the medications ever helped with my pain anyway. If anything, they only made my pain worse."

• Hop...
• December 18, 2016

For Ankylosing Spondylitis "After fourth injections, started light-headed, nausea, feel like diarrhea constant, ear drainage, white stuff in eyes, very tired, sleeping ten to fourteen hours a day. Doctor will not call me back. Don't know what to do!!!!!"

• Des...
• Taken for 1 to 6 months
• April 16, 2018

For Ankylosing Spondylitis "In January, I felt that Enbrel stopped working for me after years of great relief. Doctor started me on Cosentyx. I have taken the 5 doses of the loading dose and feel horrible! Diarrhea, irritable bowel, terrible mouth sores, light-headed, and general malaise. I never had bowel issues before this. Doctor wants me to give it more time (I'm due for an injection this week), but the side effects have thrown my life into a tailspin! I want my Enbrel life back, this is no way to live. I have to plan my work around access to a bathroom in a hurry, and I speak funny because the sores all over my tongue hurt while speaking."

• Tin...
• Taken for 1 to 6 months
• February 5, 2018

For Ankylosing Spondylitis "Stated this drug for Ankylosing spondylitis as in October after other biologics stopped working on 150 mg monthly. Very lightheaded, fatigued joints, sore, tired all the time. I don't think this one has helped at all. I have a review with rheumatologist on 20th Feb (1st review since starting this biologic). I'm gonna tell him it is no better. I've had AS since 2001, so I know by now what works. I found Enbrel was the best one for me till it stopped working."

• GMR...
• January 4, 2018

For Ankylosing Spondylitis "This drug caused me nothing but grief! It was not worth the side effects for the tiny fraction of relief! By month 3, I had a bad case of tonsillitis, which I could not get rid of! I always felt ill, with swollen glands, tired, and very fatigued! Even after a tonsillectomy, which was horrible and never healed right, I feel like garbage!"

• Pau...
• Taken for 1 to 2 years
• February 19, 2021

For Ankylosing Spondylitis "I have been using COSENTYX for 12 months. It was scary. Constant fatigue, stomach problems, terrible stagnation. I couldn’t go normally or roll over in bed. My spine and knees became completely flexed. Convulsions in the legs began."

• ASe...
• November 7, 2016

For Ankylosing Spondylitis "I finished the loading dose with no improvement. My doctor upped me to 300 mg. I'm on month 4, I'm very fatigued and still in pain, so I'm not impressed with it. I'm also experiencing mouth sores."

• and...
• Taken for 6 months to 1 year
• December 8, 2018

For Ankylosing Spondylitis "This is simply horrible... diarrhea, fatigue, more pain. Novartis, change this drug."

• Anonymous
• Taken for 2 to 5 years
• June 23, 2022

For Psoriasis "I've been on Cosentyx for 2 years now, has helped with psoriasis greatly but does nothing for my psoriatic arthritis. Injection day I get a bad headache, aches, and fatigue."