Medically reviewed by Drugs.com. Last updated on Jul 9, 2020.
Applies to the following strengths: 30 mg; 10 mg-20 mg-30 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Psoriatic Arthritis
-Day 1: 10 mg orally once a day (AM)
-Day 2: 10 mg orally twice a day (AM and PM)
-Day 3: 10 mg orally once a day (AM); 20 mg orally once a day (PM)
-Day 4: 20 mg orally twice a day (AM and PM)
-Day 5: 20 mg orally once a day (AM); 30 mg orally once a day (PM)
Maintenance dose: 30 mg orally twice a day (AM and PM)
Comments: This titration is intended to reduce the gastrointestinal symptoms associated with initial therapy.
Use: Treatment of adult patients with active psoriatic arthritis
Renal Dose Adjustments
Mild to moderate renal impairment: Data not available.
Severe renal impairment (CrCl less than 30 mL/min):
-Initial dosage: Titrate using only the AM schedule listed above and skip the PM doses.
-Maintenance dose: 30 mg orally once a day (AM)
Liver Dose Adjustments
No adjustment recommended
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
Data not available
-Administer without regard to meals.
-Do not crush, split, or chew the tablets.
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