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User Reviews for Apremilast

Also known as: Otezla

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Apremilast.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Plaque Psoriasis 78 reviews 19 medications
   
6.2
Psoriatic Arthritis 57 reviews 59 medications
   
5.3
Summary of Apremilast reviews 135 reviews 5.8

Reviews for Apremilast

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Otezla (apremilast) for Plaque Psoriasis: "This medication , for me , did not work at all. I took I think it was 2 pills a day and it didn't do anything at all except make me sick."

   
1.0

cheltz December 2, 2016

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Otezla (apremilast) for Plaque Psoriasis: "I have severe plaque psoriasis. I have tried coal tar shampoo, steroids, creams, lotions, injections to get rid of it. In less than 2 weeks I went from embarrassing plaque on my forehead, all over my scalp, behind my ears, hand, foot, chest and torso to the plaque being mostly gone, no more flaking skin, and the redness is starting to subside. I haven't felt this comfortable in my own skin in years. Yes some of the stomach issues aren't great but I'll take side effects that will go away once my body gets used to the medicine vs being embarrassed to go on dates."

   
10

Jaunty Whovian November 30, 2016

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Otezla (apremilast) for Plaque Psoriasis: "I had a little bit of an upset stomach once and two nights where I didn't get a full night sleep. Otezla worked within days and I am 99% clear. After 30 years of psoriasis affecting almost every area of my life in some way, I am enjoying such relief."

   
10

Kastania (taken for 1 to 6 months) November 23, 2016

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Otezla (apremilast) for Plaque Psoriasis: "I have been on Otezla since February. My insurance would not cover it so I am part of the company's bridge program. My psoriasis is completely gone--I haven't had normal, clear skin since I was a baby and I am 36. I finally can wear shorts and tank tops without being self-conscious that my scaly, red skin is ugly and people are looking at it. When I first started the medication I did have some bad headaches and nausea. It went away after a few weeks, if you just stick with it. I recently went away and forgot to bring the Otezla with me so I didn't take it for about 5 days, and now that I am back on it, I have headaches and nausea again but I anticipate that they will subside like they did before. I haven't had any other side effects."

   
9.0

JM9094 November 22, 2016

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Otezla (apremilast) for Psoriatic Arthritis: "So it's been 2 months now..I have been self controlling a little as I had a headache from hell.. only two times tho.. so why it's random I do not understand.. but it's so bad I can't touch it with 10 Tylenol.. it's crippling. BUT.. even so..I hate psoriasis so bad.. my life is altered by it..I continued on the Otezla with half the dose for a while.. back to full dosage.. but my psoriasis had returned due to the reduced dosage.. hoping it goes away again and those headaches as well.. nothing else is troubling.. the headaches need to subside so I can function normally at life and my job!"

   
7.0

Margot928 November 15, 2016

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Otezla (apremilast) for Plaque Psoriasis: "I just started otezla this morning!!! Obviously I haven't seen any results but I'm hopeful!!! I will be posting every week to let everyone know my results!!! "

   
5.0

Glenda0120 (taken for less than 1 month) November 14, 2016

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Otezla (apremilast) for Psoriatic Arthritis: "I have mod/severe RA overlapping with PSA. I developed a worsening of Psoriasis on Humira. I stopped Humira and DR wanted me to try Otezla to clear my Psoriasis. I can say this is the worst drug i have ever taken. I had a severe migraine for 5 days. I had very low energy levels, loss of appetite and nausea. I also developed really bad spasms. I took Methotrexate for 5 years and didn't feel this bad. I stopped Otezla going back to Humira and Methotrexate... I hope!"

   
1.0

RLT (taken for less than 1 month) November 11, 2016

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Otezla (apremilast) for Plaque Psoriasis: "My psoriasis started about 14 years ago and only gotten worse. Ten days ago I started Otezla, So far it has worked great. My scalp has already cleared up for the most part and all the spots on my legs and body are looking very good! No side affects as of yet."

   
10

BiggTime November 4, 2016

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Otezla (apremilast) for Plaque Psoriasis: "I am starting otezla sometime next week and I really hope it's works!!! I've had psoriasis since I was 16 years old (I'm 37 now) and I hate it! I'm constantly itching and making myself bleed! I'm a woman and I can't even shave my legs! I've tried so many creams and study drugs I lost count and some have worked for a little bit but then stopped working! I've even tried Stelara which worked for about 5-6 months but that drug also stopped working! My hubby and I have been together going on 18 years and we have 2 wonderful kids together, ages 15 & 12 and I can honestly say they have been my rock!!! Some days are better then others and sometimes I do even go outside for a walk but most of the time I'm inside, looking out the window!"

   
5.0

Glenda8592 November 2, 2016

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Otezla (apremilast) for Plaque Psoriasis: "Just one week in and my scalp is almost 100% clear. MY forehead is 100% clear. MY stomach , sides, back and legs have stopped producing scales and is starting to clear to a light pink , not red and angry anymore. THE only side effect I am having thus far is the tension headaches , in which I started taking i.b. profin when I start feeling it come on. So far I am very pleased with the medication."

   
9.0

Shawn S (taken for less than 1 month) October 30, 2016

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Otezla (apremilast) for Psoriatic Arthritis: "I have been taking this medication for a little over 2 months for scalp psoriasis and psoriatic arthritis. I have been lucky and experienced no adverse side effects except for several minutes of minor nausea during the first week or so of beginning it. My scalp cleared almost completely within 2-3 weeks. The itchiness is gone as well. The swelling in my hands has decreased about 20 to 25 percent and I am hoping for more as I reach the 4 to 5 month mark. I was able to remove a ring that I was sure would need to be cut off. I also have had no other side effects that others have reportedsuch as mood changes, headache, diarrhea, etc. I want others to know about good experiences so they won't be scared off. I will report back soon."

   
8.0

MLCAN (taken for 1 to 6 months) October 27, 2016

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Otezla (apremilast) for Psoriatic Arthritis: "Started taking otezla 12 days ago. I have experienced headache, nausea, fatigue, swollen and painful joints, upper right abdominal pain, swollen belly on the right side, feet pain, back pain, mild diarrhea, no ambition, hoarsness, light colored stools. I still have to take indomethician for joint inflammation and pain. I thought this drug would relieve my pain and prevent inflammation and further joint damage, instead it has made it worse. I don't see the advantage of continuing to use it along with an anti-inflammatory drug. I might as well stick with indomethicin."

   
1.0

Baby31 (taken for less than 1 month) October 25, 2016

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Otezla (apremilast) for Plaque Psoriasis: "I have been on Otezla for one month now and my psoriasis is almost clear and no itching! I have scalp and ear psoriasis and it also comes down on my forehead..now you can see where it was by the discoloring but no scales! I have had virtually no side effects. Once in a while a slight headache that feels more like a sinus ache over one eye. No weight change. No nausea. Some wakefullness at night, but no tiredness during the day. I also take Tramadol for back pain. I don't see a big change in joint pain, but am hopeful for some relief. Happy so far!!"

   
9.0

Margot928 October 19, 2016

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Otezla (apremilast) for Plaque Psoriasis: "I've always had mild psoriasis growing up since my grandma and dad had it. This year I stopped using clobatelsol propitiate tropical cream and my psoriasis got so bad I finally turned to western medicine!! I tried ortzela starter pack for two months and lost about 10 pounds, thank god, but my psoriasis seems like it got worse!!! I'm going to stop taking the medicine as it has spread all over my body and face :("

   
1.0

Nanseelove (taken for 1 to 6 months) October 15, 2016

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Otezla (apremilast) for Psoriatic Arthritis: "When I started otezla, I was having moderate arthritis affects. Right away I had head and neck pain. Throughout the 4 months I was on it, I lost 10 lbs, no appetite, nausea, bad flu flares, sometimes rapid heartbeat and no discernable relief. At 4 month mark I experienced a massive spasming of my scalp and neck muscles. As in tetany. You need your neck to sit up, lay down, walk, drive..I couldn't do anything. I like to think my pain threshold is high, but this brought me to my knees. I've been on more Prednisone with otezla then ever before..just to counteract all the flares, tendon pain. I'm off otezla now for 4 days, and still cannot move my neck properly. I hope with time it goes away. No benefits, lots of aggravation. Not a good med for"

   
3.0

Waterbug100 October 1, 2016

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Otezla (apremilast) for Psoriatic Arthritis: "I started this in March, by The end of Aug this med stopped working. It did a pretty good job of clearing up the Psorisis but my joint pain is thru the roof. My hands are progressively getting worse. It doesn't touch my RA. Instead of taking me off of it my Rheumy added MTX which I don't tolerate well. So I'm taking myself off. I got so bloated, and gassy thru the starter pack. I GAINED 20lbs! Not sure if it's the med or my increase in pain has me sidelined. I currently have tons of congestion which I have had for 3 months! DONE WITH THIS STUFF ,"

   
2.0

SouthernMommy (taken for 6 months to 1 year) October 1, 2016

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Otezla (apremilast) for Plaque Psoriasis: "I have been taking Otzela since March 26, 2016 (6 mos). I had the typical GI and headache issues that are common but I have also been struggling with a chronic cough. After years of being in a "remission", the psoriasis starting returning a couple of years ago and I had a severe flair last winter that would not respond to anything. 90% of my arms and legs were covered, with many lesions on my lower back and ears. The Otzela has cleared the psoriasis about 95% but now to the cough. In July, I stopped coughing at night and I hoped my body was adjusting but alas not. I caught a cold and the cough is worse than ever. I am going to taper off, resolve the cough and restart at a lower dose and hoping for a compromise."

   
8.0

JeanGirl September 30, 2016

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Otezla (apremilast) for Plaque Psoriasis: "SO far so good! Otezla customer service are the best! I have just started Otezla and no side effects at all -- in fact it seems I have more energy and less itching of my scalp already! No headaches or stomach issues, but will keep an eye out for that later. I am so happy to be able to try this drug as the biologics scare me with cancer issues. I will keep in touch!"

   
9.0

Margo928 September 29, 2016

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Otezla (apremilast) for Psoriatic Arthritis: "It is hard for me to rate this. I have Psoriasis and psoriatic arthritis. I have been taking Otezla for 9 months now. Within weeks my severe psoriasis had cleared. However, my arthritis is worse. At first, it seemed to stop the swelling a little. I have to say it was about 5 months before all the swelling and severe pain came back. While the pain was never completely gone, it was never this bad. Not even before Otezla. My muscles in the back of my legs hurt, and on the bottom of my right foot. I am having trouble walking. I also take hydrocodone for pain. I was taking the hydrocodone for two years and was hoping to get off with Otezla. Not going to happen. Has anybody had dental problems. I have had 3 teeth crack in the past 6 months."

   
4.0

sherlocky loo September 28, 2016

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Otezla (apremilast) for Plaque Psoriasis: "I have been on Otezla for about 18 months and am very satisfied. The only side effect has been the loose stool that most people have experienced. Prior to taking this medication I was getting 12 to 15 shots per month on my scalp and all over my legs directly into the outbreaks. Additionally was using prescribed creams, lotions and shampoo. My scalp was so bad that the psoriasis covered a patch of skin cancer that was probably growing for over a year. It was detected as I insisted on a biopsy of the area because that one area was not responding to treatment. Except for one or two small patches my skin is free and clear. Insurance is a problem, however, these is a prescription assistance program available and you can be reimbursed."

   
9.0

Anonymous (taken for 1 to 2 years) September 20, 2016

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Otezla (apremilast) for Psoriatic Arthritis: "had flu like body aches, constant urge to defecate and brutal migraines from day 3. fatigue was all consuming. rather deal with the joint pain!!"

   
1.0

dr. baker (taken for less than 1 month) September 19, 2016

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Otezla (apremilast) for Plaque Psoriasis: "I've been on Otezla a little over a year now and I think I will be stopping tomorrow after I visit my dermatologist. The Pros, much of my psoriasis cleared within weeks, especially on my neck and scalp. When doing UV treatments with the Otezla I was near 95% clear. I had all the side effects like tension headaches, stomach issues, and weight loss. However, I would take that and clearer skin over my psoriasis. I've had psoriasis for 24 years now and I have tried everything from steroid creams, UV, and biologic injections. I thought Otezla was the best! However, over the last month I have been experiencing anxiety and depression. I get stressed out so easily and having panic attacks has never been me. I cannot function normally."

   
5.0

Lesser Evil September 12, 2016

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Otezla (apremilast) for Psoriatic Arthritis: "My dermatologist put me on this medication using starter packs while they worked with the insurance to approve it. I lost my appetite completely I was exhausted, I almost lost my hearing and I got a serious upper respiratory infection. I had constant diarrhea and nausea and practically no sleep. I had to quit when I got the respiratory infection as I could hardly breathe. Why on earth is more testing not done with these drugs. The pharmaceutical companies churn our arthritis medication one after the other all of them with horrible side affects and outrageous pricing. How dare they try to charge almost $3000 a month for a drug with such poor results. Back to methotrexate and ibuprofen at least I can afford them."

   
2.0

Fionnd (taken for 1 to 6 months) September 12, 2016

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Otezla (apremilast) for Psoriatic Arthritis: "I have now been on otezla for the magic 4 months the company says it takes to improve. I am so much worse now. My arthritis is so bad I can hardly use my hands they are so swollen and painful, most of my joints are swollen and painful, and my psoriasis has gotten worse. I wish I had stayed on Enbrel, and as will be going back on it as soon as possible. I did not have any adverse side effects, it just wasn't effective for me."

   
1.0

maxsmemaw (taken for 1 to 6 months) September 7, 2016

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Otezla (apremilast) for Plaque Psoriasis: "I was prescribed Otezla 10 days ago for severe scalp and ear psoriasis. My dermatologist gave me the starter pack while I was waiting for insurance approval (which just obtained) and in this short period of time, I have noticed a nearly 50 percent reduction of the itchiness and scaling, which was so bad that it often bled and my scalp was painful from just a shower. I have a salt-water pool and the water stung so bad I tried not to get my head wet. I am astounded that I am already seeing a difference. I am even more astounded that I have had zero side effects. I was prepared for nausea, diarreah, and headaches - anything to get relief from the misery of constant scratching, scabing, and just plain pain. It hurt to even brush my hair."

   
9.0

Jaklyn (taken for less than 1 month) September 4, 2016

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