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User Reviews for Apremilast

Also known as: Otezla

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Learn more about Apremilast.

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Condition Avg. Ratings Reviews Compare
Plaque Psoriasis
5.8
   
138 reviews 23 medications
Psoriatic Arthritis
5.2
   
75 reviews 64 medications
Summary of Apremilast reviews 5.5 213 reviews

Reviews for Apremilast

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Otezla (apremilast) for Plaque Psoriasis: "Have had psoriasis for 42 years, legs, arms, trunk. Afraid to take biologics because of side effects. Started Otezla and started clearing patches up on arms and trunk after 6 weeks, had light headaches and loose stools for couple weeks but subsided. I've been on it for 15 months and it's not clearing up any more if my skin. It seems stalled after starting out so well. I thought it was finally the miracle for psoriasis, but doesn't seem to be. The maker of Otezla actually pays for mine 100% and I have insurance that would not cover it at first but they will now."

   
5.0

Hey Mikey (taken for 1 to 2 years) December 10, 2017

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Otezla (apremilast) for Plaque Psoriasis: "I have completed the Starter Pack week one. For 36 years, I have had psoriasis over my entire trunk, legs, arms, and feet. I have used phototherapy, creams, ointments, cortizone topical and tanning beds with very little relief. I am currently receiving Otezla free from Celgene. I have had NO side-effects to date, but my psoriasis has cleared from my entire body by 90%!! I have never had such clear skin in the last 36 years!! I am so grateful to this company for providing me with this wonder drug which my insurance would not cover! I know my results are not common, but I am thankful for each day that I am not miserable from this terrible affliction!"

Anonymous (taken for less than 1 month) December 3, 2017

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Otezla (apremilast) for Psoriatic Arthritis: "I have been taking Otezla for psoriatic arthritis as well as psoriasis. At first I thought it was a miracle drug helping with the pain and the patches. I did have terrible (and I mean terrible) problems with my stomach. While it improved slightly, after a year and a half it still kills my stomach. I am going to get off of it because it stopped helping with the pain and my skin is worsening. I stuck with it despite the nonstop bowel movements (and headaches) because I thought it was helping, but now that I'm reverting back it isn't worth the nearly debilitating side effects."

Anonymous (taken for 1 to 2 years) November 30, 2017

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Otezla (apremilast) for Plaque Psoriasis: "I'm 62 years old with a complicated medical history. I have chronic pain (RSD), Diabetes and now Plaque Psoriasis (mainly scalp). I began with Otezla starter pack increasing dose even slower than the pack. I've never had side effects but Otezla changed that. I had headaches, loose stool and stomach pains. My insurance denied paying and at $3000/month, I couldn't afford it. I stopped for two weeks and then got more samples. I used the starter pack dosing since I had already used Otezla. Big mistake. Stomach was on fire every time I ate. Stopped again for 2 weeks and restarted very slowly. Doing much better and its helping. However if insurance doesn't cover it, I have to stop. ¯\_(ツ)_/¯"

   
7.0

Markdoc55 November 13, 2017

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Otezla (apremilast) for Psoriatic Arthritis: "I was diagnosed with HLA-B27 (a specific protein on your white blood cells that can be a sign of autoimmune disease) Dr told me I had Psoriatic Arthritis gave me a starter pack of Otezla took for 12 days , which all of stiffness and joint pain left, I am also on Phentermine and Topimirate for weight loss, so I didn’t experience any headache, however I did get somewhat depressed and no energy to do anything, I ran out of the starter pack had to get another but was off of it for 3 days, while off of it I noticed my mood was better and back to normal, but this morning oh my all my stiffness and pain are back so I am goin back on the new starter pack and try to deal with mood thing because this pain is crazy, I also do have a sinus head cold that I have had for 4 days but I kinda chalked that off to the time of year and weather!"

   
7.0

Kandi313 (taken for less than 1 month) November 13, 2017

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Otezla (apremilast) for Plaque Psoriasis: "I have suffered from plaque psoriasis for 20 years. I have tried creams, biologics, etc. Nothing worked for long or it had severe side effects. After several years of no medical treatment, I contacted my dermatologist to see if there was something else to try. I'm so glad I did. My skin is 90% clear, the best it's looked in decades. Side effects are an upset stomach and loose stools. I make sure I take a dose with food and early in the day. If I take it too late in the day, I will not see sleep soundly."

   
9.0

TracySwaglione2002 November 11, 2017

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Otezla (apremilast) for Plaque Psoriasis: "I have been taking Otezla for about 6 months, after about 6 years of Neotigason and various creams. The Neotigason can have side effects on the liver and requires constant monitoring via blood tests, with the result that I was often non compliant with horrible flare-ups of my moderate to bad plaque psoriasis. Now with Otezla, the outcome is fantastic, 98 percent clear up, with just light pink marks on forearms left. Scalp and face totally clear which is great. If I cut down on a dose, it comes back. Had the odd headache, loose stools, odd patch if insomnia. Can live with all of it. Biggest problem is the cost, extremely expensive, even after being subsidized here in Israel."

Topadvocate (taken for 6 months to 1 year) November 4, 2017

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Otezla (apremilast) for Plaque Psoriasis: "I started September 1st 2017 with the starter pack. Had the usual symptoms that everyone is talking about. Toughed it out. Then the monthly dosage started after the starter pack finished. About the third and a half week I had pain in the lower left side of my stomach. I stopped the pill for a week. Pain was gone. So I thought lets try again. I then started the pill only in the evenings. Basically half dose. Since the start till now October 20 2017, my plaque psoriasis has been noticeably reduced. Halving the half (1 pill a day) dose has also calmed my usual symptoms. I am tempted to start back on 2 pills a day again."

   
6.0

Ralphus (taken for 1 to 6 months) October 23, 2017

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Otezla (apremilast) for Plaque Psoriasis: "I am not happy. After taking the medication for a year without any effects (positive or negative) I stopped taking the medication. Why should I bother to take it if i did not have any reduction on psoriasis?"

   
2.0

olguta October 15, 2017

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Otezla (apremilast) for Plaque Psoriasis: "Been on one month now and I'm now 75% clear which I can tolerate. The first few days did have slight nausea and diarrhea but nothing severe! No headaches, no sleep problems, no depression, and haven't had any more nausea or diarrhea. Has cleared scalp, legs, back and even nail psoriasis 100%. I'm only left with my stubborn spots on knees and elbows but the scaling and redness has improved greatly, only thin scales and slight discoloration left on those stubborn problem areas which I can live with. Happy with this drug and hope it continues!"

Anonymous242424242 (taken for 1 to 6 months) October 13, 2017

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Otezla (apremilast) for Plaque Psoriasis: "I have had psoriasis since I was six years old (I am 22 now). My worst area has always been my scalp and elbows, with it extending to my torso, back, and legs. Recently I have been under stress and I'm overweight so my psoriasis is the worse it has ever been. My dermatologist decided on otezla. They warn you about the most common side effects: nausea and diarrhea. I experienced these symptoms within two days of starting the medication. I will say right away it started working, clearing my scalp first (which is the first area it tends to start working on). Now I am somebody who struggles with having diarrhea and can't deal with it emotionally. I had to stop the drug after only three weeks, which sucked because it was working amazing for me."

   
6.0

mdgdhdfg October 9, 2017

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Otezla (apremilast) for Plaque Psoriasis: "After reading endless negativity reviews, I feel almost guilty to say how big a fan I am of Otezla. I developed mild to severe psoriasis around 33. Tried all the ointments, cortisone injections, laser and light treatment options with light/temporary relief. Started Otezla 1/1/17, had immediate positive results. Little nausea at first along with slight headache & bowel issues, all side effects subsided within a couple of weeks. Haven't lost any weight. Not depressed or sad. In fact, quite the opposite - due to clear skin/confidence I'm happier than I've been in years. I'm 99% clear! Never thought I'd be able to wear little shorts & be at the beach with clear skin again. Big fan & feel blessed. Hope this helped if you're on the fence"

   
9.0

Barbie0917 October 3, 2017

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Otezla (apremilast) for Plaque Psoriasis: "Tried this med for 6 days; had to stop. Almost went crazy! Severe depression, cried at the drop of a hat, extremely nauseous, IBS & so irritable, it nearly cost my relationship!"

LuJean September 23, 2017

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Otezla (apremilast) for Plaque Psoriasis: "I started with the starter pack, and when I went from 10 mg to 20 mg, it was a train wreck. I actually couldn't function, my entire body was like hell no... massive fatigue, cramping in the stomach, fogginess, couldn't go to work. I feel like I had 30 beers. I hope this works out for you if you are trying it, but I'm finished with this.gl"

   
1.0

Train Wreck1 September 19, 2017

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Otezla (apremilast) for Psoriatic Arthritis: "Been on Otezzla for about 6 months. The first few months I thought my prayers had been answered. My skin cleared up by 75 percent in 3 months. I have psoriasis and psoriatic arthritis. My pain had decreased as well. I did have stomach issues, severe headaches and major pressure in my ears and can hardly hear! The medication has quit working. Not clearing up my scales or itching at all! And the pain! The pain in my fingers, elbows and feet is worse than ever. I'm up all during the night from joint pain, now have nerve pain in my feet and cannot open a bottle of water in the mornings. Very sad this didn't work out because I refuse to take immune suppression medication."

   
5.0

Denny789824 September 17, 2017

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Otezla (apremilast) for Psoriatic Arthritis: "On otezla for a short time 4 weeks must come off it because of surgery right shoulder rotator cuff. Up to this point minor side effects but did cause some sleep issues which could also be contributed my upcoming surgery. Had such good results with Biologicals for 15 yrs. until they lost there effectiveness. Now as I get older 67 would like to try something less immunosuppressive. Not encouraged by comments I read. But everyone is different so I will stick it out for four months"

   
4.0

Mattcat (taken for 1 to 6 months) September 12, 2017

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Otezla (apremilast) for Plaque Psoriasis: "I am just about to hit my 16th week of Otezla (which they say is about as long as it takes to start working). I am not noticing a massive improvement- some spots in certain areas are down to just pink inflamed dots (legs and torso), while other areas actually seem to be worse (elbows, ears, scalp). I found the first week or two I had a lot of loose bowel movements, and my appetite was suppressed, but that quickly went away. I cannot comment on headaches as I live with a neurological disorder. I have a drug plan through work, and luckily this drug is covered, so I will continue this drug until Christmas and then go from there."

hookings21 (taken for 1 to 6 months) September 10, 2017

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Otezla (apremilast) for Plaque Psoriasis: "The very first day I took otezla it felt like I was going to vomit but I didn't so I continued taking it. Then after taking the second and third ones for the evening I started having pains on my right shoulder. I thought I slept funny. But the pain was still bearable and I thought it will go away so I continued taking it although I began having a hard time sleeping. The seventh day/evening it got worst. Right after I took the evening pill the pain on my right shoulder went all the way to my arms and my right fingers. I was up until 3 in the morning I couldn't sleep and thought of going to the urgent care. The next morning, both of my arms are in pain, I decided to stopped taking Otezla. I should have not taken it in the beginning."

   
1.0

biggest mistake September 8, 2017

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Otezla (apremilast) for Psoriatic Arthritis: "I took Otezla twice, two years apart. My first experience helped my psoriasis and psoriatic arthritis within 3 months with minimal side effects. I had loose stool for a couple of days and a mild headache. THEN I developed a very aggressive breast cancer and was advised to stop Otezla.. I underwent chemotherapy, bilateral mastectomies and reconstruction. One year later, I began taking Otezla again because my psoriasis and PA came back with a vengeance, as predicted. Four months into treatment, I developed breast cancer in my sternum. Once again, I quit the Otezla and have since undergone radiation treatment. I did not tick the boxes for a patient at high risk for breast cancer. I feel my cancer may well have been a direct result of Otezla"

   
1.0

Joschally September 1, 2017

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Otezla (apremilast) for Plaque Psoriasis: "I'm five days in and had to stop taking Otezla due to the horrible side effect from this drug. I'm having every side effects you could think of. Nausea, diarrhea, headache, vomiting, pain in my upper stomach so bad it was unbearable and chest pains. I haven't spoke to my rheumatologist yet but I choose on my own to stop taking this drug. Nothing helped for pain and I couldn't keep any good or liquids down. Joint pain as well as back pains started getting worse."

   
1.0

Anonymous (taken for less than 1 month) August 29, 2017

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For Psoriatic Arthritis: "I lasted 3 weeks and a bit more on this drug. If you don't like sleep, love headaches and stomach pain all day every day and to top it all off irritability then this is the drug for you!!! I went from being my usual calm self to an enraged, confused moron. Not to mention the heart palpitations. Maybe just me, needless to say I clearly don't recommend it."

   
1.0

Ryan B August 16, 2017

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Otezla (apremilast) for Plaque Psoriasis: "This medicine is miracle to me. I have psoriasis from last 7 years. I tried all diff type of med from prescription to over the counter tablets and creams but nothing was working. I was getting depressed and anti social. For me it was looks like my Dr was just making money from me and not doing enough. I changed my dermatologist and got new one, then my new Doc prescribed me Otezla which I start taking twice a day sometime once a day. I seen my skin start getting clear. Today was the first day my hands was totally clear. I was so happy. I lost few pounds while I am taking this pills also I am more sexually active. Thanks to the creator of this pill!!"

Vaneet August 12, 2017

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Otezla (apremilast) for Plaque Psoriasis: "Third and last day on Otezla. Took fourth 10mg pill at 6:30am with breakfast. Slight headache, no nausea, no depression. Not feeling myself. I had to make a conscious effort not to 'zone out' all day. BP is up. Had disturbing dreams last night and woke up with pain in hands, ankles, and back. Every plaque is itching like crazy. I have stopped taking this drug."

   
1.0

projectotezla August 11, 2017

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Otezla (apremilast) for Plaque Psoriasis: "I am now on my eighth day ,and besides the slight nausea and the frequent bowel movements throughout the day (it's not affecting my working and taking care of my son's needs),I think that I'm going to stick it out. I was on the Enbrel sure click last year and because I caught an infection and my system was severely compromised, I was admitted to the hospital, in serious condition; so, no more Enbrel. I stayed clear for a few months after being taken off of it, but once the psoriasis came back ,it went rampant....please check back in a few weeks with an update"

   
4.0

MsT12171 (taken for less than 1 month) August 8, 2017

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Otezla (apremilast) for Plaque Psoriasis: "This was for my Guttate Psoriasis; PROS: Easy to take and digest. No adverse side effects other than occasion so headache. CONS: Didn't really work. Improved flaming and dryness but red patches are still there and still itchy/burning skin. If you have mild psoriasis it may work but for anybody with moderate to severe I would be very doubtful. Let down as I was hoping it would be a wonder drug and it's definitely not. Some creams work better."

   
3.0

Aurastar56 (taken for 1 to 6 months) August 2, 2017

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