Secukinumab Side Effects

In Summary

Commonly reported side effects of secukinumab include: infection and nasopharyngitis. Other side effects include: diarrhea. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to secukinumab: subcutaneous powder for solution, subcutaneous solution

Along with its needed effects, secukinumab may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking secukinumab:

More Common

• Fever
• headache
• muscle aches
• sore throat
• stuffy or runny nose
• unusual tiredness or weakness

Less Common

• Body aches or pain
• chills
• cough
• difficulty with breathing
• ear congestion
• hives or welts, itching, or skin rash
• loss of voice
• redness of the skin

Incidence Not Known

• Diarrhea
• difficulty with swallowing
• dizziness
• fast heartbeat
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• rectal bleeding
• severe diarrhea
• severe stomach pain
• tightness in the chest
• weight loss

For Healthcare Professionals

Applies to secukinumab: subcutaneous powder for injection, subcutaneous solution

Dermatologic

Uncommon (0.1% to 1%): Tinea pedis, urticaria^[Ref]

Gastrointestinal

Common (1% to 10%): Diarrhea, oral herpes

Uncommon (0.1% to 1%): Oral candidiasis

Frequency not reported: Exacerbation of inflammatory bowel disease (IBD)^[Ref]

Hypersensitivity

Rare (less than 0.1%): Anaphylaxis^[Ref]

Immunologic

Uncommon (0.1% to 1%): Immunogenicity

Frequency not reported: Candida infections, herpes viral infections, staphylococcal skin infections, infections requiring treatment (increased as serum concentration of this drug is increased), neutropenia^[Ref]

Respiratory

Very common (10% or more): Nasopharyngitis (up to 12.3%)

Common (1% to 10%): Upper respiratory tract infection, rhinitis, pharyngitis, rhinorrhea^[Ref]

Hematologic

Uncommon (0.1% to 1%): Neutropenia^[Ref]

Ocular

Uncommon (0.1% to 1%): Conjunctivitis^[Ref]

Other

Uncommon (0.1% to 1%): Otitis externa^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer