Ixekizumab Side Effects
Applies to ixekizumab: subcutaneous solution.
Serious side effects of Ixekizumab
Along with its needed effects, ixekizumab may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking ixekizumab:
- Body aches or pain
- burning, dry, or itching eyes
- difficulty with breathing
- discharge or excessive tearing
- ear congestion
- itching in the genital or other skin areas
- loss of voice
- lower back or side pain
- painful or difficult urination
- redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
- runny or stuffy nose
- scaling of the skin
- sore mouth or tongue
- sore throat
- unusual tiredness or weakness
- white patches in the mouth or on the tongue
- Chest tightness
- difficulty swallowing
- fast heartbeat
- general feeling of discomfort or illness
- hives, itching, skin rash
- joint pain
- loss of appetite
- muscle aches and pains
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- trouble sleeping
- Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- rectal bleeding
- redness of the skin
- severe diarrhea
- severe stomach pain
Other side effects of Ixekizumab
Some side effects of ixekizumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
For Healthcare Professionals
Applies to ixekizumab: subcutaneous solution.
Most commonly reported adverse reactions with a frequency of 1% or greater were injection site reactions, upper respiratory tract infections, nausea, and tinea infections.
Common (1% to 10%): Hypertension
Common (1% to 10%): Urticaria, herpes simplex (mucocutaneous)
Common (1% to 10%): Nausea, diarrhea, oral herpes, pharyngitis, oropharyngeal pain
Uncommon (0.1% to 1%): Oral candidiasis, inflammatory bowel disease, abdominal pain
Rare (0.01% to 0.1%): Oesophageal candidiasis
Common (1% to 10%): Vulvovaginal candidiasis, menstrual disorder, irregular menstruation, uterine dilation, curettage
Uncommon (0.1% to 1%): Ovarian cyst
Frequency not reported: Bacterial vaginosis, bartholinitis
Very common (10% or more): Neutropenia (Up to 11%)
Very common (10% or more): Infections ( Up to 27%), immunogenicity (Up to 22%)
Common (1% to 10%): Tinea infections, influenza
Uncommon (0.1% to 1%): Serious infections[Ref]
Very common (10% or more): Injection site reactions (Up to 17%)
Frequency not reported: Erythema, pain
Postmarketing reports: Esophageal candidiasis[Ref]
Common (1% to 10%): Arthralgia, back pain, myalgia
Uncommon (0.1% to 1%): Musculoskeletal pain, neck pain, non-cardiac chest pain
Uncommon (0.1% to 1%): Headache, dizziness
Common (1% to 10%): Conjunctivitis
Uncommon (0.1% to 1%): Iridocyclitis, eye pain[Ref]
Common (1% to 10%): Anti-drug antibodies development
Uncommon (0.1% to 1%): Fatigue, pyrexia
Common (1% to 10%): Depression
Very common (10% or more): Upper respiratory tract infections (including nasopharyngitis and rhinovirus infection) (Up to 16%)
Uncommon (0.1% to 1%): Rhinitis, bronchitis, sinusitis[Ref]
Uncommon (0.1% to 1%): Increased blood creatine phosphokinase, increased aspartate aminotransferase
Common (1% to 10%): Dysuria
Frequently asked questions
- How long before Taltz works?
- Is weight gain a side effect of Taltz?
- Can I drink alcohol with Taltz?
- What are the new drugs for plaque psoriasis?
- How does Taltz work?
More about ixekizumab
- Check interactions
- Compare alternatives
- Reviews (203)
- Dosage information
- During pregnancy
- Drug class: interleukin inhibitors
- En español
Related treatment guides
1. Cerner Multum, Inc. UK Summary of Product Characteristics.
2. Cerner Multum, Inc. Australian Product Information.
3. Product Information. Taltz Autoinjector (ixekizumab). Eli Lilly and Company. 2016.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.