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User Reviews for Ixekizumab

Also known as: Taltz

Ixekizumab has an average rating of 7.1 out of 10 from a total of 130 ratings on 65% of those users who reviewed Ixekizumab reported a positive effect, while 25% reported a negative effect.

Condition Avg. Rating Reviews Compare
Plaque Psoriasis  
98 reviews 40 medications
Psoriatic Arthritis  
18 reviews 75 medications
12 reviews 317 medications
Ankylosing Spondylitis  
2 reviews 144 medications
Summary of Ixekizumab reviews 7.1 130 reviews

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Ixekizumab

Breannacourtneyy · Taken for 1 to 6 months February 25, 2021

Taltz (ixekizumab) for Psoriasis: “I've been on Taltz now for almost a month. I started with 2 auto injections at once and then now doing 80 mg every 2 weeks. I have plaque and guttate psoriasis which my dermatologist has classified as erythrodermic psoriasis. My entire body is covered and this has never happened to me before. I’m 27 years old and I've had this flare up for 8 months.. now I’m experiencing something new though since starting the Taltz. I've done 3 injections so far. My flare up hasn’t gotten better at all like whatsoever. Not even a little bit. In fact, my patches are getting larger than they ever been. I have no side effects so far from taking taltz, but is it normal for my flare up flakes to combine and get larger?? I’m not experiencing new flakes.. but the ones I have are starting to connect together and form larger portions. I’m literally covered from chest down. Also in my scalp and back of my neck. I’m starting to feel defeated and I just hope that this doesn’t mean it’s not working ):”

5 / 10
Joseppi · Taken for 5 to 10 years February 20, 2021

Taltz (ixekizumab) for Psoriatic Arthritis: “Taltz saved my life. 80% covered with horrible plaques. Five years now and I am still 100% clear. I think that it is a miracle drug. I have done them all. For those struggling, just keep trying. You will find one that works. It took me About 10 different drugs until Taltz. Now I am at the beach everyday without having to hide my body. Don’t give up hope. We are all in this together.”

10 / 10
Midwest February 18, 2021

Taltz (ixekizumab) for Psoriasis: “Guttate psoriasis over 50% of legs for 20 years. I’ve tried light therapy, steroid creams, Tazorac, Otezla and Cosentyx. Otezla made me nauseous and did nothing. Creams would help slightly, but it took weeks and also left my skin raw and peeling. Cosentyx for 9 months made them slightly smaller, but no real noticeable change. Just had my week 2 dose of Taltz. I have to say it might be just the initial loading dose of a biologic repeating, but it is actually better. A long way to go- but I am hopeful. And I agree that the autoinjector pen is ridiculously painful. Brings tears and I am pretty tough. It is short lived though and praying this biologic finally makes it to where I can wear shorts .”

7 / 10

Frequently asked questions

Catz22 · Taken for 1 to 6 months August 19, 2020

Taltz (ixekizumab) for Psoriatic Arthritis: “37 years old, have psoriatic arthritis for 11 years, although do believe Humira gave me psoriasis and Cosentyx fixed it. Cosentyx caused massive lung nodules and biopsies showed inflammation. Discontinued and they went away after 6 months. Was on Cimzia for 6+years and did well, then stopped working. Almost seemed to make things worse. Started Taltz. In a month time, have felt unwell, nausea, stomach issues- burning, discomfort, eye blurriness, increase migraines, mucus increased (drainage), trouble sleeping, and reactivate shingles virus. My joints felt stiff, painful but muted? Does that make sense? Haven’t felt good since taking it, and don’t believe I want to keep seeing what it does. I just completed the first two injections.”

2 / 10
Lefty · Taken for 6 months to 1 year April 11, 2020

Taltz (ixekizumab) for Plaque Psoriasis: “This has been a wonder drug. I tried Otezla and Humana and neither got rid of my plaques. After being on Taltz for about 2 months, all of my plaques are completely gone. Zero side effects. I now have been on Taltz for a year and my plaques have not returned. This is the best I have ever felt since first being diagnosed with psoriasis as a kid.”

10 / 10
Rob · Taken for 1 to 6 months April 2, 2020

Taltz (ixekizumab) for Ankylosing Spondylitis: “After a long streak of feeling good on Enbrel which wore off after 9 years tried a round of alternatives. Failed results For the last 3 years from Humira, Cosentyx and Cimzia from likely being too adjusted. Pleasantly surprised by early improvements on Taltz. Hoping it sustains. Only 3 months in but felt obligated to share early positivity that I hope will sustain and grow. Definitely took the 3 months to feel improvements which have lasted 1-2 weeks/month.”

8 / 10
Shay · Taken for 1 to 6 months January 17, 2019

Taltz (ixekizumab) for Psoriatic Arthritis: “Had been on methotrexate, Otezla and 3 months of Humira. None were working with the psoriatic arthritis or the psoriasis plaques. My rheumatologist finally tried Talz and within 4 days, my skin was 75% clearer and arthritis pains were less. After 3 months, NO plaques and very little joint swelling or pain. I am feeling almost like I did before psoriasis and PsA.”

10 / 10

More FAQ

Homebody · Taken for 6 months to 1 year June 27, 2020

Taltz (ixekizumab) for Plaque Psoriasis: “Thia drug worked pretty well while I was using it and the company has very friendly/cooperative service representatives. Be that as it may, you need to understand that this is a lifetime investment if you start using it. If you have to stop using it for any reason at all, like I did, please don't start. My psoriasis came back much worse and the areas of my body affected increased 5x. I don't know why this is, but it is important that prospective users are aware of this hidden side effect.”

9 / 10
Pain management · Taken for 1 to 6 months October 24, 2019

Taltz (ixekizumab) for Psoriatic Arthritis: “I have had this God forsaken disease of Psoriatic Arthritis too long as most of you. I am on shot 4 loading dose and it has taken me from wanting to die to what I call now living such a awful place My swelling and pain in my head neck sand shoulders is almost perfect. But then there is my right arm and shoulder. It seems like my tendons are spinning and they tighten up so much it will burst my skin if I do not keep manipulating it around in circles? You can’t make this stuff up. When I walk it tightens it and makes me feel as if I am slowing down and it gets harder and harder until I have to literally spin around in place to relieve the tendon. I am at a loss. I was so hoping this would work and it sort of did. My mind is burnt. And my will is broken. Prayers for all. Has anyone else ever had these symptoms??”

3 / 10
DWOK · Taken for 1 to 6 months June 7, 2016

Taltz (ixekizumab) for Plaque Psoriasis: “This drug is what my Doc put me on when I asked for Cosentyx. She said it had a little bit better success rate and might be a little cheaper. She also told me that I would only have to do labs once per year. I have moderate plaque P from head to toe. I should say HAD. I am 99% clear at 4 weeks. I only have light spots where plaques used to be. The only other biologics I have had are Humira, which worked for a year or so, and Otezla, which did not work at all. The only side effects I have had have been a slight touch of digestive trouble and maybe one day of mild (flu like) body aches. My cost after insurance and copay assistance is 5 bucks per month. Needless to say I am super happy so far. So far so great.”

10 / 10
Lou Lou · Taken for 1 to 6 months April 2, 2020

Taltz (ixekizumab) for Psoriatic Arthritis: “Horrible! Talz was great for skin but nothing else! My joints felt worse and I was sick all the time! Tired like you would not believe. I ended up with numerous respiratory infections and yeast infections! Yuck! Sadly this didn’t work for me!”

1 / 10
Robso · Taken for 1 to 6 months November 14, 2019

Taltz (ixekizumab) for Plaque Psoriasis: “Was on the Otezla pill for about 4 months, it began to work for my Psoriasis, on lower shins,and elbows, but then stopped. The my skin doc. recommended the Taltz. Took this, and I did get very clear on this, but began also noticing terrible, yes terrible side effects as it really affected my immune system. I got so fungal related infections - ring worm, I got athletes foot, my stomach was killing me, I developed fungal infections all over my body. Still fighting a serious fungal infection in my sinuses, and now today had xrays of my lungs, thinking i must have pneumonia . Now may also have serious fungal infection in my lungs. I am so mad at Lilly for putting out such garbage, as Talz makes people very sick. I understand that 27 % of all people get very sick on Taltz. I have not noticed in a while now, any more commercials on TV, about Taltz. Did they take this off the market? I am still very ill, even being off of this drug, for 4 months. But lowered my immune system, and got me VERY Sick, I plan on Suing”

1 / 10
Hgriffin80 · Taken for 1 to 2 years September 8, 2018

Taltz (ixekizumab) for Plaque Psoriasis: “I’ve been using Taltz for a year now. I’ve suffered with psoriasis and psoriatic arthritis for about 20 years. I’ve tried everything and nothing seemed to work completely. Some meds worked okay on the plaques but didn’t touch the joint pain! When I started using Taltz I noticed a difference in my skin in a bout 4 weeks. After 3 months I was completely clear! I said completely clear! After having plaques for decades you can imagine how ecstatic that made me. My joint pain has improved so much that I’m able to take dance lessons! Yes, the injection is the most painful medication I have ever taken but the benefits are totally worth it. I can play with my kids and dance with my husband! I can wear a bathing suit on vacation or wear a skirt or short sleeves to the office! I wish the shot itself wasn’t so painful but for the first time in my life I’m not a prisoner to my psoriasis and joint pain!”

9 / 10
Sid January 4, 2019

Taltz (ixekizumab) for Plaque Psoriasis: “The benefits of Taltz for me are fantastic. I've had plaque psoriasis since I was 16. I’m 54 and have been clear for 2 years. It also helps with my osteoarthritis pain. I know the injections can hurt. I allow the injector to reach room temperature. Then I ice the injection site. It's hit or miss on pain. But if being slapped across the face once a month cleared my psoriasis, I’d do that too. Just saying.....”

10 / 10
Taltzhappy August 25, 2018

Taltz (ixekizumab) for Plaque Psoriasis: “35 y/o female issues with mild psoriasis for decades and in April became severe after having strep. I was covered. My scalp was covered and spots started to appear on forehead and face. My back completely covered and arms and legs looked like a horrible case of chicken pox. Started w/steroid shot that seemed it was going to work , a week later it came back with a vengeance! Then tried other injections (also immuno suppressors) same thing, acted like they were working but a week in it was back full force. I began Taltz with 2 injections then 1 every 2 weeks for 6 doses then 1 a month. I am beginning the 1 a month regimen now. I was completely clear in days. I haven’t been sick and work in a high risk profession of catching colds/ flu/ etc.The injections are painful but quick. First the injections left large welts but that has subsided. I would take that any day over the psoriasis. I recommend taking the medication out of fridge couple hours before injection and follow it with an ice pack”

10 / 10
Chris July 27, 2020

Taltz (ixekizumab) for Psoriatic Arthritis: “I was diagnosed with Psoriatic Arthritis (PA) 14 years ago I have been on everything. My rheumatologist recommended the Taltz. Just took my first shot yesterday. My leg is very sore and red. I have been getting weird nasal sensations as well. I think I'm done trying all medications. I plan on taking a food sensitivity test and looking into natural supplements.”

1 / 10
GB · Taken for 6 months to 1 year November 28, 2020

Taltz (ixekizumab) for Psoriatic Arthritis: “Taltz injection has really worked for me. Started on Temfya and it did not work for my joint pain. Taltz has cleared up my skin and 99% of joint pain. However, the injection has been painful and I do get a site allergic reaction ever time I take the shot for about a year now. Have been taking it on my stomach. Tried my thigh once and it was very painful there, so I stopped.”

10 / 10
Scousejill April 24, 2019

Taltz (ixekizumab) for Plaque Psoriasis: “Hi, I have suffered with plaque psoriasis for over 40 years, I have tried several treatments over the years, I tried Methotrexate, this was a miracle drug,.but everything runs its course I guess, I’ve tried other Biological drugs, which haven’t worked, then my dermatologist suggested I try Taltz , I was a little nervous, but by now the pain from my plaque Psorasis was so sore, Anyway I took my first double dose of Taltz 2 weeks ago, i injected into my stomach, either side of my belly button, and , yes, it does sting, but it wasn’t unbearable. Within days I started to see a difference, my legs were looking less red and painful, and less itchy, it felt amazing, seeing such a difference so soon, I look 60% better already, I can’t believe it. I’m about to take my next injection and I’m hoping the progress continues, I can’t wait, no side effects up to now, I feel great, trying to stay positive, this medication looks like we’re going in the right direction to find a cure.”

10 / 10
Taltzrocks November 10, 2016

Taltz (ixekizumab) for Plaque Psoriasis: “I have been on this study for nearly 3 years. My psoriasis has been a problem since I was young and have dealt with it for 30 years! I have tried all sort of different drugs over that time and nothing has given even close to the same results as this. It truly is a miracle. I take one shot a month and I'm clean and clear of everything! Just like others have posted it took about 2 weeks to show big improvements and by a month in you wouldn't ever guess I suffer from severe plaque psoriasis. I thank all the doctors and nurses that have helped me through this process and I'm very happy to see this hit the market! Hope it works as good for you as it has for me.”

10 / 10
Mike · Taken for 1 to 6 months June 30, 2019

Taltz (ixekizumab) for Psoriatic Arthritis: “I have palm plantar pustular psoriasis, Hidradenitis Suppurativa and psoriatic arthritis. I’ve been through Humira, Enbrel, Stelara, cosentyx, and Otezla. I started with a new rheumatologist and she proscribed Taltz. I’m on week 8 of the loading dose and I hate this medicine. For one thing, it doesn’t help with my constant stiffness and pain from the arthritis, it hasn’t stopped my nails from pitting, and worst of all, I have constant severe breakouts of folliculitis. I’ve been taking doxycycline for over 30 days and still have pimples all over my body. Dermatologist suggested I stop with the Taltz. Additionally, it is unquestionably the most painful injection of all the biologics I’ve tried.”

1 / 10
Deanski · Taken for 6 months to 1 year May 2, 2019

Taltz (ixekizumab) for Plaque Psoriasis: “After dealing with psoriasis for over 50 years, I am finally totally clear. I started Taltz 9 months ago with concerns about taking a biologic. So far, I have had no side effects and I am looking forward to wearing summer clothes without embarrassment. The shots do hurt but well worth the results. It helps to swear while injecting. I qualify for a $25 co-pay per month. If not for that, I would never be able to afford it. It's a life saver for me.”

10 / 10
Scott-123987 September 9, 2016

Taltz (ixekizumab) for Plaque Psoriasis: “This stuff is absolutely amazing. I've been on enbrel, stelara, humira, methotrexate, topicals, and none of them have ever done this well. Within 3 days of the first injections I started to see clearing. I thought, no way! But it has only continued to get better. I'm about to inject my week 5 dose and most of my areas are scale free. My self esteem has gone way up. My wife isn't complaining about flakes in the bed. No bloody spots on the sheets from picking. I can wear dark colored shirts, short sleeves, no sleeves again; and not be concerned about people staring. Yes, the injection stings. Yes sometimes the injection leaves a swelling under the skin. But for me, it is completely worth it.”

10 / 10
ashanks · Taken for 1 to 2 years June 29, 2020

Taltz (ixekizumab) for Plaque Psoriasis: “I've had plaque Psoriasis since I was around 8 which is uncommon, for a kid that is. I've tried so many creams, powders and oils, but nothing seems to make it go away. Around 16 my plaques probably covered more area than my actual skin. Anyways all through this time I tried everything to try and make it stop and nothing. First month of taking taltz my plaques had shrunk by 50% and by the next it was completely gone. If you struggle with psoriasis I suggest you at least try it if nothing else is working because it worked great for me with minimal to no side effects.”

9 / 10
Rache · Taken for 1 to 6 months February 16, 2019

Taltz (ixekizumab) for Plaque Psoriasis: “I have been on several biologics over the past few years for psoriasis and psoriatic arthritis. This is the ONLY one that has worked. I work in sales and the disease process had severely affected both my professional and personal life. My former boyfriend broke up with me due to the skin lesions associated with this disease process. My immune system is a bit weaker but my quality of life has drastically improved. I am beyond thankful.”

10 / 10
Lindy · Taken for 1 to 6 months May 26, 2019

Taltz (ixekizumab) for Plaque Psoriasis: “I have tried everything for 24 years and only Talz has worked. My Psoriasis has gone completely!!! I was covered with it. I feel so much better. Thank you for giving my quality of life back. God bless you.”

Susie · Taken for 1 to 2 years September 14, 2018

Taltz (ixekizumab) for Plaque Psoriasis: “I’m 61 and have had psoriasis since I was 8 years old, have tried every treatment. Tried Otezla and it affected my liver, kidneys so got off that. I started Taltz a year and half ago with fabulous results. In the last 8 weeks I have never ever been so sick with sore throat, swollen lymph node on the right side, cough and sticky phlegm. I feel lousy on and off and this throat infection won’t do away. I have had every blood test, strep test and everything checks out fine. I’m on hold now for the next shot. Wondering if anyone else has had this problem and what I should do. I have to go back to work, but if I’m this sick all the it worth it. Any other comments would be appreciated”

Meg · Taken for 1 to 6 months April 18, 2019

Taltz (ixekizumab) for Psoriasis: “I started taltz around 5 months ago. I previously have tried different tablets and injections none of which really improved my psoriasis and one of which lowered my immune system so low that I was admitted to hospital for 5 days. So understandably I was a bit hesitant especially with such mixed reviews. And at the age of 26 I had little hope of anything ever improving my psoriasis. Taltz has been an absolute miracle for me, I had psoriasis on 80% of my body and after just the 2nd injection my psoriasis was completely gone. Granted the injections are slightly painful but I’d take 10 second of pain once a month over a life time of psoriasis any day.”

9 / 10
Hannah August 15, 2018

Taltz (ixekizumab) for Plaque Psoriasis: “I have been on Taltz for about 8 months now, and before Taltz NOTHING even subsided my psoriasis. I am now completely clear of the plaques, (still have the white spots that occur when the plaques go away.) The only downside to this medicine is it really does weaken your immune system. I was never sick before this medicine and now I am ALWAYS sick. Strep throat, multiple infections, colds, everything. I've gotten so sick I've almost considered this medicine not worth it even though it's effective. What's even worse is that I'm on a trial for the child version of the medicine. Overall really effective medicine, completely clear, yet always really sick.”

7 / 10

This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.