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Ixekizumab use while Breastfeeding

Drugs containing Ixekizumab: Taltz

Medically reviewed by Drugs.com. Last updated on Dec 30, 2020.

Ixekizumab Levels and Effects while Breastfeeding

Summary of Use during Lactation

No information is available on the clinical use of ixekizumab during breastfeeding. Because ixekizumab is a large protein molecule with a molecular weight of 146,000 Da, the amount in milk is likely to be very low. It is also likely to be partially destroyed in the infant's gastrointestinal tract and absorption by the infant is probably minimal. Some professional guidelines feel that the drug is acceptable to use during breastfeeding.[1] Until more data become available, ixekizumab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

(Psoriasis) Adalimumab, Etanercept, Infliximab, Phototherapy, Tretinoin

References

1.
Smith CH, Yiu ZZN, Bale T, et al. British Association of Dermatologists guidelines for biologic therapy for psoriasis 2020: A rapid update. Br J Dermatol. 2020;183:628–37. [PubMed: 32189327]

Substance Identification

Substance Name

Ixekizumab

CAS Registry Number

1143503-69-8

Drug Class

Breast Feeding

Lactation

Antibodies, Monoclonal, Humanized

Dermatologic Agents

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Further information

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