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Medications for Ankylosing Spondylitis

Spondylitis involves inflammation of one or more vertebrae. Ankylosing spondylitis is a chronic inflammatory disease that affects the joints between the vertebrae of the spine, and the joints between the spine and the pelvis. It eventually causes the affected vertebrae to fuse or grow together.

Drugs used to treat Ankylosing Spondylitis

The following list of medications are in some way related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Humira 7.1 69 reviews
Rx B N

Generic name: adalimumab systemic

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Enbrel 7.6 51 reviews
Rx B N

Generic name: etanercept systemic

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Celebrex 3.3 4 reviews
Rx C N

Generic name: celecoxib systemic

Drug class: cox-2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Remicade 6.3 12 reviews
Rx B N

Generic name: infliximab systemic

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Cosentyx 4.0 29 reviews
Rx B N

Generic name: secukinumab systemic

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Simponi 6.5 24 reviews
Rx B N

Generic name: golimumab systemic

Drug class: TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

diclofenac 7.6 16 reviews
Rx D N X

Generic name: diclofenac systemic

Brand names:  Voltaren, Cataflam

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

prednisone 9.3 3 reviews
Rx C N

Generic name: prednisone systemic

Brand name:  Rayos

Drug class: glucocorticoids

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Cimzia 6.2 11 reviews
Rx B N

Generic name: certolizumab systemic

Drug class: TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

adalimumab 7.1 71 reviews
Rx B N

Generic name: adalimumab systemic

Brand names:  Humira, Amjevita, Cyltezo, Hyrimoz, Abrilada, Hadlima, Hulio, Yusimry …show all

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

etanercept 7.7 53 reviews
Rx B N

Generic name: etanercept systemic

Brand names:  Enbrel, Erelzi, Eticovo

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

infliximab 6.4 16 reviews
Rx B N

Generic name: infliximab systemic

Brand names:  Remicade, Renflexis, Avsola, Inflectra, Ixifi …show all

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

naproxen 7.2 12 reviews
Rx/OTC C N X

Generic name: naproxen systemic

Brand names:  Aleve, Naprosyn, Naprelan, Anaprox, All Day Pain Relief, All Day Relief, Anaprox-DS, Flanax Pain Reliever, Aflaxen, EC-Naprosyn, Midol Extended Relief …show all

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Taltz 4.4 5 reviews
Rx N

Generic name: ixekizumab systemic

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

golimumab 6.7 29 reviews
Rx B N

Generic name: golimumab systemic

Brand names:  Simponi, Simponi Aria

Drug class: TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Renflexis 9.0 1 review
Rx B N

Generic name: infliximab systemic

Drug class: TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

secukinumab 4.1 31 reviews
Rx B N

Generic name: secukinumab systemic

Brand name:  Cosentyx

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

certolizumab 6.2 11 reviews
Rx B N

Generic name: certolizumab systemic

Brand name:  Cimzia

Drug class: TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Avsola 1.0 1 review
Rx B N

Generic name: infliximab systemic

Drug class: TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Dipentum Off-label Rate Add review
Rx C N

Generic name: olsalazine systemic

Drug class: 5-aminosalicylates

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

Inflectra 10 1 review
Rx B N

Generic name: infliximab systemic

Drug class: TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ixekizumab 4.4 5 reviews
Rx N

Generic name: ixekizumab systemic

Brand name:  Taltz

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Rinvoq Rate Add review
Rx N

Generic name: upadacitinib systemic

Drug class: antirheumatics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

upadacitinib Rate Add review
Rx N

Generic name: upadacitinib systemic

Brand name:  Rinvoq

Drug class: antirheumatics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

celecoxib 4.5 5 reviews
Rx C N

Generic name: celecoxib systemic

Brand name:  Celebrex

Drug class: cox-2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Learn more about Ankylosing Spondylitis

Care guides

Symptoms and treatments

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.