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Ixekizumab for Psoriasis User Reviews

Brand names: Taltz

Rating: 8.2

Ixekizumab has an average rating of 8.2 out of 10 from a total of 27 reviews for the treatment of psoriasis. 70% of reviewers reported a positive experience, while 7% reported a negative experience.

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Reviews for Ixekizumab

  • Meg...
  • Taken for 1 to 6 months
  • April 18, 2019

Ixekizumab "I started Taltz around 5 months ago. I previously have tried different tablets and injections, none of which really improved my psoriasis, and one of which lowered my immune system so low that I was admitted to the hospital for 5 days. So understandably, I was a bit hesitant, especially with such mixed reviews. And at the age of 26, I had little hope of anything ever improving my psoriasis. Taltz has been an absolute miracle for me, I had psoriasis on 80% of my body, and after just the 2nd injection, my psoriasis was completely gone. Granted, the injections are slightly painful, but I’d take 10 seconds of pain once a month over a lifetime of psoriasis any day."

9 / 10
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39 Report
  • Jod...
  • Taken for 1 to 6 months
  • March 6, 2019

Ixekizumab "Amazing! I just got done with my 4th injection (technically 5th if you count the 2 injections received on the first visit). My skin is 75% clearer. My psoriasis had gotten so bad over the past 4 years, and I tried all the ointments and steroid creams, and nothing worked. My dermatologist recommended Taltz, and it has changed my life. For the first time in years, I have smooth skin! Most of the dry patches are gone, and I only have a few red spots where the dry skin was, but it's smooth to touch! I have had 0 side effects except for a little pain during the injection. Occasionally, I'll feel a slight lump in the injection site, but it goes away within 2 days. I have been getting headaches, but only occasionally... nothing I can't handle. This will be the first year I might actually put shorts on with confidence!"

10 / 10
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32 Report
  • Kar...
  • Taken for 1 to 6 months
  • November 20, 2020

Ixekizumab "I've only been on Taltz for a couple of months. Psoriasis cleared up almost immediately, no side effects yet. Steroid topicals used to cause hands to crack, so I'm happy to be done with them. The auto-injector hurts really bad in the thigh. When my doctor first showed me how to inject it, he almost got punched, and I called him many names. I did not want to do the second injection and almost pulled it out when I did it myself. Tried numbing creams and ice packs since, but it still really hurt. Decided to give the belly a try. Still used a cold pack first just because injection to the stomach seemed like it would be worse. I literally felt almost nothing. If you are suffering the pain of injecting in the legs, try the stomach. If you are going to start with auto-injectors, skip the leg and just go straight to the stomach. Or, when you do your first two injections, take the first to the stomach and the second to the leg so you can see for yourself. The difference in pain level is unbelievable."

10 / 10
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24 Report

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Frequently asked questions

  • Boo...
  • Taken for 1 to 2 years
  • March 24, 2019

Ixekizumab "This injection has been a miracle drug for me. I have suffered with scalp psoriasis since I was about 12 years old. I am now 38. I tried several prescription ointments/topicals, natural treatments, and every shampoo that I could find for scalp psoriasis, but nothing ever helped or got rid of it. The worst flare-up occurred when my dad was diagnosed with cancer and passed. I could feel the hardened skin on my scalp when I would tilt my head back. It was awful. Taltz completely cleared my scalp psoriasis in a matter of weeks. No more chemical-filled shampoos destroying my scalp and hair. No more stress or embarrassment of going to a hairdresser. This injection is AMAZING."

10 / 10
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28 Report
  • Bus...
  • Taken for 1 to 2 years
  • October 10, 2020

Ixekizumab "I have been on Taltz for a year now. It has helped me a lot. I’ve noticed that people have said that the injections are painful. When I first started, it says to inject in the leg, so I did, it was the worst pain from an injection I ever felt. But after that, I inject in the abdomen and it does not hardly hurt, and sometimes I have no injection pain. I do the abdomen always now."

9 / 10
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15 Report

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  • cbu...
  • Taken for 1 to 6 months
  • May 7, 2019

Ixekizumab "I have been taking Taltz for moderate guttate psoriasis and am on week 23 now. I do have much clearer skin than I ever did, and injections have gotten easier. The only drawback is how often I'm catching infections and having other not-so-fun side effects with experience. I had strep throat for almost 2 months and went through 2 antibiotics. Sore throat never stopped due to a sinus infection on top of that when strep left. Saw 3 doctors and had 2 positive strep tests. Even the Taltz pharmacist said it was just hard to clear it up due to a lesser immune system. Just saw my dermatologist today, who basically told me the doctors don't know what they are talking about, and he does because he is the one who prescribes it all the time. His words. I just couldn't believe this doctor talking to me like this, like I've not been experiencing this-it was like he was trying to convince me that I was wrong! I've never had so many health issues and infections in such a short period of time. It can't be anything but the Taltz...but I love my clear-ish skin!"

7 / 10
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18 Report
  • Gra...
  • Taken for 1 to 2 years
  • March 9, 2022

Ixekizumab "I had immediate results. I was really impressed with how smooth my skin was. All areas were gone, and it all started with the first dose. My downfall was I ended up with folliculitis. A week or so, my head would itch so bad, and then I started getting sore areas on my head. I mean, they were so bad that I couldn’t even lay my head on my pillow. Then these areas would start getting bigger and bigger, and they would drain pus out of them. I lost the hair in these areas. I was just fortunate that my hair did grow back."

7 / 10
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9 Report

More FAQ

  • Kyl...
  • Taken for 1 to 2 years
  • November 10, 2020

Ixekizumab "I had psoriasis all my life and have been given topical meds up until my sophomore year in college (which never worked). I got a new doctor, and he was finally willing to give me something more intense after so many others said I didn’t need it (Taltz). Although the injections are tough because I’ve never liked injections, this medicine has been a miracle. My psoriasis has completely gone away, and I am finally happy with my skin. 110% recommend this for anybody that struggles with psoriasis. My insurance didn’t cover it, but my doctor was able to get me the medicine with very reasonable monthly payments."

10 / 10
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10 Report
  • WRA...
  • Taken for 1 to 6 months
  • October 24, 2021

Ixekizumab "I’m sixty-four and have been living with moderate to severe psoriasis since my late teens. I’ve tried it all: UVB, creams, ointments, etc., nothing got rid of my psoriasis. Major breakouts left me in pain, bleeding, peeling, and depression. When Enbrel came out, I thought it was a Godsend, it knocked it way down to maybe one percent of my body but never got rid of it until Taltz came along. I’m 100% clear now. I’m very happy with the results. Been using it three months now."

10 / 10
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6 Report
  • Chi...
  • Taken for 6 months to 1 year
  • July 9, 2021

Ixekizumab "I could not believe in a matter of a couple of doses my skin was clearing up. I had tried diets, other drugs, tanning beds, red light therapy, skin products, steroids. I went all natural with everything on my body, and nothing worked. Then Taltz, and I look normal again at 43. I developed psoriasis when I turned 40, it took me three years to find my answer."

10 / 10
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6 Report
  • Hyj...
  • Taken for 1 to 2 years
  • November 10, 2020

Ixekizumab "I was switched to Taltz after 10 years on Humira for severe plaque psoriasis. I had side effects from the start: severe exhaustion, mouth ulcers, red burning eyes, exaggerated response at the injection site, felt like I had the flu for two days after injection, hair loss, extreme folliculitis, etc. In addition, Taltz didn’t even start to combat the psoriasis that affects my toenails, which has gotten so painful I had to buy a half size larger in trainers. I gave it a year and a half, as I was part of a study, but thankfully, I’m going back to Humira! The exhaustion was the worst part; it’s really affected me."

6 / 10
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  • Con...
  • Taken for 6 months to 1 year
  • June 9, 2022

Ixekizumab "My 30-year-old son was started on Taltz for a moderate case of psoriasis and was on it for around 7 months when, out of the blue, he developed a very severe case of ulcerative colitis. It was classified as pan-colitis involving his entire colon. The GI doctor who did his colonoscopy said it was the worst case he had ever seen and listed it as such on the scale they use to determine severity. My son had NEVER had any kind of issue with his bowel before. He ended up hospitalized in extreme pain for over two weeks, and at one point, we were concerned they were going to have to remove his entire colon because they couldn't stop the pain or bleeding with steroids. He couldn't eat and was put on TPN for nutrition. He ended up losing 40 pounds. He eventually responded to a medication called Remicade and was able to leave the hospital. He has been informed by his doctors that he will have ulcerative colitis for the rest of his life and all the pain, discomfort, and expense that will entail."

1 / 10
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  • Bre...
  • Taken for 1 to 6 months
  • February 25, 2021

Ixekizumab "I've been on Taltz now for almost a month. I started with 2 auto-injections at once and then now doing 80 mg every 2 weeks. I have plaque and guttate psoriasis, which my dermatologist has classified as erythrodermic psoriasis. My entire body is covered, and this has never happened to me before. I’m 27 years old, and I've had this flare-up for 8 months. Now I’m experiencing something new, though, since starting the Taltz. I've done 3 injections so far. My flare-up hasn’t gotten better at all, like whatsoever. Not even a little bit. In fact, my patches are getting larger than they ever have been. I have no side effects so far from taking Taltz, but is it normal for my flare-up flakes to combine and get larger? I’m not experiencing new flakes, but the ones I have are starting to connect together and form larger portions. I’m literally covered from chest down, also in my scalp and back of my neck. I’m starting to feel defeated, and I just hope that this doesn’t mean it’s not working :)"

5 / 10
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  • Mid...
  • February 18, 2021

Ixekizumab "Guttate psoriasis over 50% of legs for 20 years. I’ve tried light therapy, steroid creams, Tazorac, Otezla, and Cosentyx. Otezla made me nauseous and did nothing. Creams would help slightly, but it took weeks and also left my skin raw and peeling. Cosentyx for 9 months made them slightly smaller, but no real noticeable change. Just had my week 2 dose of Taltz. I have to say it might be just the initial loading dose of a biologic repeating, but it is actually better. A long way to go, but I am hopeful. And I agree that the autoinjector pen is ridiculously painful. Brings tears, and I am pretty tough. It is short-lived though, and praying this biologic finally makes it to where I can wear shorts."

7 / 10
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  • Anonymous
  • Taken for 2 to 5 years
  • August 23, 2021

Ixekizumab "The company really helped me get insurance approval. Took a while, and some issues with insurance were all resolved in time and worth it. This medication helped me with psoriasis, clearing completely at 6 months, even the scalp. Helped PsA back pain and all joint pain took longer, but I really noticed changes at 1 year. I didn't have any side effects except some nausea and exacerbated IBS. Nausea helped with anti-nausea watch. IBS may be worsening, though. Afraid to get off due to the time it took for it to work, build up, and approvals."

8 / 10
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  • jca...
  • Taken for 2 to 5 years
  • August 2, 2023

Ixekizumab "I was diagnosed with 'moderate to severe psoriasis and/or plaque psoriasis' by a dermatologist circa 1995 at age 54. Some of the new 'biologic' drugs like Enbrel were about to enter the market at that time. The Psoriasis Foundation, as a patient advocate, worked to get this class of 'biologic' drugs placed in a legal category that required health insurance providers doing business in the State of California to cover the cost for this type of drug as a treatment for psoriasis. I had been in several drug trials at the UCSF medical school in San Francisco for Enbrel in 2005 and 2006. The drug worked very well for controlling my psoriasis. In 2007, I started using Enbrel full-time when I began my coverage with Medicare. I switched to Taltz circa 2018. I still take one dose or 'shot' of Taltz per month. It seems to effectively control my psoriasis very effectively."

10 / 10
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  • She...
  • Taken for 1 to 2 years
  • August 20, 2022

Ixekizumab "I had psoriasis that the dermatologist diagnosed with a biopsy and spondylitis in the spine found with X-rays, as well as back pain, swollen toes, and more. Taltz pushed psoriasis into remission (it only acts up occasionally on the scalp, and I treat it with fungicide). Psoriatic arthritis and spondylitis are better too. All symptoms are minor now. Could not do much until I got Taltz. I had pain, swelling, cramping, and had given up working out and more. Now I am plaque free, can go to the gym, and am getting my life back thanks to Taltz. It's a very painful injection, but it's over in a few minutes, and I am grateful. Use ice, Tylenol, and Benadryl with a lidocaine patch 30 minutes before injection. Have the doctor give you your injection (not you), and it's worth it. Use a syringe, not an auto-injector pen. I had IBS before Taltz, and Linzess helps my tummy. Nausea managed with magnesium gummies and ginger caps in the morning. Insurance paid because of the biopsy, X-rays, and the doctor diagnosed all properly. My insurance covers, and the most paid was $5.00 per month. I think it's a great drug as long as it is injected right."

10 / 10
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  • Ric...
  • Taken for 1 to 6 months
  • July 24, 2021

Ixekizumab "This is the most painful thing I have EVER injected. Why? Imagine a red-hot poker searing a hole through your skin, that's what it feels like to me. I don't know if I can continue this stuff, the pain is ridiculous."

2 / 10
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  • Tal...
  • Taken for 6 months to 1 year
  • November 19, 2019

"In Poland, the insurance covers up to 2 years of therapy. Unfortunately, after 2 years of treatment, patients will be just kicked out of that drug program. Results of this specific treatment are just unbelievable. I lost ALL plaque just after 3 days of taking the initial dose, without using any topical medications! The only negative side is the feeling of having an upper respiratory tract infection, however, the increased CRP level is not observed."

9 / 10
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  • Anonymous
  • Taken for 1 to 2 years
  • October 7, 2024

Ixekizumab "Taltz worked well for the first year. I have now developed some resistance (tachyphylaxis) to the drug as my scalp psoriasis has returned, as well as some spots on my chest. I have been on almost every biologic over the past 24 years and switched to Taltz due to its safety profile and its positive effect on psoriatic psoriasis. Has anyone else experienced this diminishing effect of Taltz after one year of use? I am considering Skyrizi but am not ready to fight with insurance as they seem to always resist changes that don't benefit them monetarily."

5 / 10
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  • ash...
  • Taken for 6 months to 1 year
  • September 4, 2020

Ixekizumab "Taltz has been very, very good for my psoriasis. The injection does hurt a lot. But it is bearable and I would take 10 seconds of a shot anyway rather than live with plaque psoriasis."

9 / 10
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8 Report
  • Zyg...
  • Taken for 6 months to 1 year
  • November 8, 2021

Ixekizumab "For psoriasis, it worked better for me than Humira or Skyrizi. For psoriatic arthritis, Humira seemed to work better than Taltz."

8 / 10
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  • syl...
  • Taken for 1 to 6 months
  • June 2, 2021

Ixekizumab "Amazing med! Started working in just 2 days!"

10 / 10
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  • Mob...
  • Taken for 1 to 2 years
  • November 1, 2023

Ixekizumab "My body is almost clean and all marks are gone. I am very much satisfied and want to recommend to all psoriasis patients."

9 / 10
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  • GBi...
  • Taken for 6 months to 1 year
  • January 19, 2024

Ixekizumab "Works great. It's almost February and I have seen no psoriasis conditions at all."

10 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

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