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How does Taltz work?

Medically reviewed by Drugs.com Last updated on Apr 22, 2020.

Official Answer

by Drugs.com

The active ingredient in Taltz, ixekizumab, is a monoclonal antibody that works by inhibiting the inflammatory response in adults with plaque psoriasis, active psoriatic arthritis, and active ankylosing spondylitis.

Taltz selectively binds with interleukin 17A (IL-17A) cytokine, a naturally occurring substance that can cause inflammation. Taltz inhibits the release of pro-inflammatory cytokines and chemokines by inhibiting the interaction of IL-17A with the IL-17 receptor.

Taltz affects the immune system. It may increase the risk of infections, which can be serious. Taltz should not be used in patients who have any symptoms of infection, unless a doctor advises otherwise. 

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