How does Taltz work?
Medically reviewed by Drugs.com. Last updated on June 10, 2020.
The active ingredient in Taltz, ixekizumab, is a monoclonal antibody that works by inhibiting the inflammatory response in adults with plaque psoriasis, active psoriatic arthritis, active ankylosing spondylitis, and non-radiographic axial spondyloarthritis.
Taltz selectively binds with interleukin 17A (IL-17A) cytokine, a naturally occurring substance that can cause inflammation. Taltz inhibits the release of pro-inflammatory cytokines and chemokines by inhibiting the interaction of IL-17A with the IL-17 receptor.
Taltz affects the immune system. It may increase the risk of infections, which can be serious. Taltz should not be used in patients who have any symptoms of infection, unless a doctor advises otherwise.
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