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Medications for Plaque Psoriasis

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Otezla 5.3 299 reviews for Otezla to treat Plaque Psoriasis Rx C N
Generic name:
apremilast systemic
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Humira 5.7 38 reviews for Humira to treat Plaque Psoriasis Rx B N
Generic name:
adalimumab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cosentyx 7.2 115 reviews for Cosentyx to treat Plaque Psoriasis Rx B N
Generic name:
secukinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Skyrizi 8.4 27 reviews for Skyrizi to treat Plaque Psoriasis Rx N
Generic name:
risankizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tremfya 7.7 46 reviews for Tremfya to treat Plaque Psoriasis Rx N
Generic name:
guselkumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Taltz 7.5 132 reviews for Taltz to treat Plaque Psoriasis Rx N
Generic name:
ixekizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Stelara 9.5 11 reviews for Stelara to treat Plaque Psoriasis Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
apremilast 5.4 318 reviews for apremilast to treat Plaque Psoriasis Rx C N
Generic name:
apremilast systemic
Brand name:
Otezla
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Zoryve 8.7 34 reviews for Zoryve to treat Plaque Psoriasis Rx N
Generic name:
roflumilast topical
Drug class:
selective phosphodiesterase-4 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
adalimumab 5.8 39 reviews for adalimumab to treat Plaque Psoriasis Rx B N
Generic name:
adalimumab systemic
Brand names:
Humira, Amjevita, Hyrimoz, Abrilada, Cyltezo, Hadlima, Hulio, Idacio, Simlandi, Yuflyma, Yusimry
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
secukinumab 7.2 118 reviews for secukinumab to treat Plaque Psoriasis Rx B N
Generic name:
secukinumab systemic
Brand name:
Cosentyx
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Vtama 8.1 32 reviews for Vtama to treat Plaque Psoriasis Rx N
Generic name:
tapinarof topical
Drug class:
topical antipsoriatics
For consumers:
dosage, side effects
For professionals:
Prescribing Information
Ilumya 8.7 3 reviews for Ilumya to treat Plaque Psoriasis Rx N
Generic name:
tildrakizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ixekizumab 7.6 134 reviews for ixekizumab to treat Plaque Psoriasis Rx N
Generic name:
ixekizumab systemic
Brand name:
Taltz
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
ustekinumab 8.8 12 reviews for ustekinumab to treat Plaque Psoriasis Rx B N
Generic name:
ustekinumab systemic
Brand names:
Stelara, Imuldosa, Otulfi, Pyzchiva, Selarsdi, Steqeyma, Wezlana, Yesintek
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Bimzelx 9.8 6 reviews for Bimzelx to treat Plaque Psoriasis Rx N
Generic name:
bimekizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
risankizumab 8.3 30 reviews for risankizumab to treat Plaque Psoriasis Rx N
Generic name:
risankizumab systemic
Brand name:
Skyrizi
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
roflumilast 8.7 34 reviews for roflumilast to treat Plaque Psoriasis Rx N
Generic name:
roflumilast topical
Brand name:
Zoryve
Drug class:
selective phosphodiesterase-4 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
tapinarof 8.1 33 reviews for tapinarof to treat Plaque Psoriasis Rx N
Generic name:
tapinarof topical
Brand name:
Vtama
Drug class:
topical antipsoriatics
For consumers:
dosage, side effects
For professionals:
AHFS DI Monograph
tildrakizumab 8.7 3 reviews for tildrakizumab to treat Plaque Psoriasis Rx N
Generic name:
tildrakizumab systemic
Brand name:
Ilumya
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
betamethasone 9.3 6 reviews for betamethasone to treat Plaque Psoriasis Rx C N
Generic name:
betamethasone topical
Brand names:
Sernivo, Luxiq
Drug class:
topical steroids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Enbrel 8.3 16 reviews for Enbrel to treat Plaque Psoriasis Rx B N
Generic name:
etanercept systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
calcipotriene 9.3 4 reviews for calcipotriene to treat Plaque Psoriasis Rx C N
Generic name:
calcipotriene topical
Brand names:
Dovonex, Calcitrene, Sorilux, Kalosar
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Taclonex 8.0 6 reviews for Taclonex to treat Plaque Psoriasis Rx C N
Generic name:
betamethasone / calcipotriene topical
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Dovonex 9.0 2 reviews for Dovonex to treat Plaque Psoriasis Rx C N
Generic name:
calcipotriene topical
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
methylprednisolone Rate Add review Rx C N
Generic name:
methylprednisolone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
betamethasone / calcipotriene 7.4 58 reviews for betamethasone / calcipotriene to treat Plaque Psoriasis Rx C N
Generic name:
betamethasone / calcipotriene topical
Brand names:
Taclonex, Enstilar, Taclonex Scalp, Wynzora
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Enstilar 7.4 44 reviews for Enstilar to treat Plaque Psoriasis Rx C N
Generic name:
betamethasone / calcipotriene topical
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
dexamethasone 7.3 3 reviews for dexamethasone to treat Plaque Psoriasis Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
etanercept 8.3 16 reviews for etanercept to treat Plaque Psoriasis Rx B N
Generic name:
etanercept systemic
Brand names:
Enbrel, Erelzi, Eticovo
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Sotyktu 6.6 13 reviews for Sotyktu to treat Plaque Psoriasis Rx N
Generic name:
deucravacitinib systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
halobetasol Rate Add review Rx C N
Generic name:
halobetasol topical
Brand names:
Lexette, Bryhali
Drug class:
topical steroids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Taclonex Scalp 8.5 2 reviews for Taclonex Scalp to treat Plaque Psoriasis Rx C N
Generic name:
betamethasone / calcipotriene topical
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
Cimzia 9.0 1 review for Cimzia to treat Plaque Psoriasis Rx B N
Generic name:
certolizumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Duobrii 8.1 14 reviews for Duobrii to treat Plaque Psoriasis Rx N
Generic name:
halobetasol / tazarotene topical
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
infliximab Rate Add review Rx B N
Generic name:
infliximab systemic
Brand names:
Remicade, Avsola, Inflectra, Ixifi, Renflexis
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Remicade Rate Add review Rx B N
Generic name:
infliximab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Sernivo Rate Add review Rx C N
Generic name:
betamethasone topical
Drug class:
topical steroids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Siliq 7.6 14 reviews for Siliq to treat Plaque Psoriasis Rx N
Generic name:
brodalumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Amjevita 10 1 review for Amjevita to treat Plaque Psoriasis Rx B N
Generic name:
adalimumab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
brodalumab 7.8 15 reviews for brodalumab to treat Plaque Psoriasis Rx N
Generic name:
brodalumab systemic
Brand name:
Siliq
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Calcitrene Rate Add review Rx C N
Generic name:
calcipotriene topical
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
guselkumab 7.8 49 reviews for guselkumab to treat Plaque Psoriasis Rx N
Generic name:
guselkumab systemic
Brand name:
Tremfya
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
hydroxyurea Off-label Rate Add review Rx D N
Generic name:
hydroxyurea systemic
Drug class:
antimetabolites
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Hyrimoz Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Sorilux Rate Add review Rx C N
Generic name:
calcipotriene topical
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
tazarotene 8.0 1 review for tazarotene to treat Plaque Psoriasis Rx X N
Generic name:
tazarotene topical
Brand name:
Tazorac
Drug class:
topical acne agents, topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Abrilada Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Avsola Rate Add review Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
bimekizumab 9.8 6 reviews for bimekizumab to treat Plaque Psoriasis Rx N
Generic name:
bimekizumab systemic
Brand name:
Bimzelx
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
certolizumab 9.0 1 review for certolizumab to treat Plaque Psoriasis Rx B N
Generic name:
certolizumab systemic
Brand name:
Cimzia
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Cyltezo Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Erelzi Rate Add review Rx B N
Generic name:
etanercept systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
Eticovo Rate Add review Rx B N
Generic name:
etanercept systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Hadlima Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
halobetasol / tazarotene 8.1 14 reviews for halobetasol / tazarotene to treat Plaque Psoriasis Rx N
Generic name:
halobetasol / tazarotene topical
Brand name:
Duobrii
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
Hulio Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Idacio Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Inflectra Rate Add review Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Ixifi Rate Add review Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
Kalosar Rate Add review Rx C N
Generic name:
calcipotriene topical
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Lexette Rate Add review Rx C N
Generic name:
halobetasol topical
Drug class:
topical steroids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Luxiq Rate Add review Rx C N
Generic name:
betamethasone topical
Drug class:
topical steroids
For consumers:
dosage, interactions, side effects
Renflexis Rate Add review Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Simlandi Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tazorac 8.0 1 review for Tazorac to treat Plaque Psoriasis Rx X N
Generic name:
tazarotene topical
Drug class:
topical acne agents, topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Yuflyma Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Yusimry Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Bryhali Rate Add review Rx C N
Generic name:
halobetasol topical
Drug class:
topical steroids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
deucravacitinib 6.6 13 reviews for deucravacitinib to treat Plaque Psoriasis Rx N
Generic name:
deucravacitinib systemic
Brand name:
Sotyktu
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Imuldosa Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
Otulfi Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Pyzchiva Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Selarsdi Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Steqeyma Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Wezlana Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Wynzora 6.0 2 reviews for Wynzora to treat Plaque Psoriasis Rx C N
Generic name:
betamethasone / calcipotriene topical
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Yesintek Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

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Frequently asked questions

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

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