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Halobetasol / tazarotene topical Side Effects

Medically reviewed by Drugs.com. Last updated on May 23, 2020.

For the Consumer

Applies to halobetasol/tazarotene topical: topical application lotion

Side effects requiring immediate medical attention

Along with its needed effects, halobetasol / tazarotene topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking halobetasol / tazarotene topical:

More common

  • Blistering, burning, crusting, drying, or flaking of the skin
  • itching, scaling, severe redness, soreness, or swelling of the skin

Less common

  • Breakdown, weakness, falling off, or wasting away of the skin
  • burning, itching, and pain in hairy areas, pus at the root of the hair
  • skin scrape or irritation
  • thinning of skin with easy bruising, especially when used on the face or areas where the skin may touch or rub together

Side effects not requiring immediate medical attention

Some side effects of halobetasol / tazarotene topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Pain at the application site

For Healthcare Professionals

Applies to halobetasol / tazarotene topical: topical lotion

Local

Common (1% to 10%): Application site pain, folliculitis, skin atrophy, excoriation, rash, skin abrasion, skin exfoliation[Ref]

Ocular

Postmarketing reports: Cataracts, glaucoma[Ref]

Dermatologic

Common (1% to 10%): Contact dermatitis

Frequency not reported: Photosensitivity, sunburn[Ref]

Endocrine

Very common (10% or more): Hypothalamic-pituitary-adrenal (HPA) axis suppression (15%)[Ref]

References

1. "Product Information. Duobrii (halobetasol-tazarotene topical)." Bausch Health US (formerly Valeant Pharmaceuticals), Bridgewater, NJ.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.