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Antimetabolites

What are Antimetabolites?

Antimetabolites are drugs that interfere with one or more enzymes or their reactions that are necessary for DNA synthesis. They affect DNA synthesis by acting as a substitute to the actual metabolites that would be used in the normal metabolism (for example antifolates interfere with the use of folic acid).

Antimetabolites are drugs used in cancer chemotherapy. Cancer cells divide more rapidly compared to normal cells so antimetabolites affect cancer cell replication more than they affect normal cell replication.

List of Antimetabolites:

View by  Brand | Generic
Drug Name Avg. Rating Reviews
Xeloda (Pro)
Generic name: capecitabine
6.6
25 reviews
Hydrea (Pro)
Generic name: hydroxyurea
7.1
7 reviews
Gemzar (Pro)
Generic name: gemcitabine
7.2
5 reviews
Otrexup (Pro)
Generic name: methotrexate
9.5
2 reviews
Rheumatrex Dose Pack (Pro)
Generic name: methotrexate
2.0
1 review
Purinethol (Pro)
Generic name: mercaptopurine
7.6
1 review
Leustatin (Pro)
Generic name: cladribine
10
1 review
Folotyn (Pro)
Generic name: pralatrexate
1.0
1 review
Fludara (Pro)
Generic name: fludarabine
6.0
1 review
Alimta (Pro)
Generic name: pemetrexed
7.5
1 review
Xatmep (Pro)
Generic name: methotrexate
No reviews
Trexall (Pro)
Generic name: methotrexate
5.0
No reviews
Tabloid (Pro)
Generic name: thioguanine
No reviews
Siklos (Pro)
Generic name: hydroxyurea
No reviews
Rasuvo (Pro)
Generic name: methotrexate
No reviews
Pemfexy
Generic name: pemetrexed
No reviews
Oforta (Pro)
Generic name: fludarabine
No reviews
Mylocel
Generic name: hydroxyurea
No reviews
Mavenclad (Pro)
Generic name: cladribine
No reviews
Infugem (Pro)
Generic name: gemcitabine
No reviews
FUDR (Pro)
Generic name: floxuridine
No reviews
Droxia (Pro)
Generic name: hydroxyurea
No reviews
DepoCyt
Generic name: cytarabine liposomal
No reviews
Dacogen (Pro)
Generic name: decitabine
No reviews
Clolar (Pro)
Generic name: clofarabine
No reviews
Arranon (Pro)
Generic name: nelarabine
No reviews
Adrucil (Pro)
Generic name: fluorouracil
10
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.