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Medications for Small Cell Lung Cancer

Other names: Cancer, Lung, Small Cell; Lung Cancer, Small Cell; SCLC

Small Cell Lung Cancer (SCLC) comprises around 15% of all lung cancer cases. Its name derives from the small, densely packed cancer cells that characterize it.

SCLC is notorious for its rapid growth and early spread to distant sites, which often limits surgical options. This type primarily affects heavy smokers.

SCLC has a high responsiveness to chemotherapy. The cancer's rapid division rate makes it vulnerable to chemotherapy agents, typically administered alongside radiation therapy for maximum efficacy. However, despite initial success, SCLC often becomes resistant to treatment over time.

Early detection remains critical for better outcomes, although SCLC is frequently diagnosed in advanced stages when treatment options are limited.

Drugs used to treat Small Cell Lung Cancer

The following list of medications are in some way related to or used in the treatment of this condition.

Filter
Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
etoposide Rate Add review
Rx D N
Generic name:
etoposide systemic
Brand names:
Toposar, Etopophos
Drug class:
mitotic inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
durvalumab Rate Add review
Rx N
Generic name:
durvalumab systemic
Brand name:
Imfinzi
Drug class:
anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
topotecan 0.0 1 review for topotecan to treat Small Cell Lung Cancer
Rx D N
Generic name:
topotecan systemic
Brand name:
Hycamtin
Drug class:
miscellaneous antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Imfinzi Rate Add review
Rx N
Generic name:
durvalumab systemic
Drug class:
anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Hycamtin Rate Add review
Rx D N
Generic name:
topotecan systemic
Drug class:
miscellaneous antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
atezolizumab Rate Add review
Rx N
Generic name:
atezolizumab systemic
Brand name:
Tecentriq
Drug class:
anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
methotrexate Rate Add review
Rx X N X
Generic name:
methotrexate systemic
Drug class:
antimetabolites, antirheumatics, antipsoriatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Toposar Rate Add review
Rx D N
Generic name:
etoposide systemic
Drug class:
mitotic inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Zepzelca Rate Add review
Rx N
Generic name:
lurbinectedin systemic
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Etopophos Rate Add review
Rx D N
Generic name:
etoposide systemic
Drug class:
mitotic inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cyclophosphamide Off-label Rate Add review
Rx D N
Generic name:
cyclophosphamide systemic
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Tecentriq Rate Add review
Rx N
Generic name:
atezolizumab systemic
Drug class:
anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
lurbinectedin Rate Add review
Rx N
Generic name:
lurbinectedin systemic
Brand name:
Zepzelca
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph

Frequently asked questions

View more FAQ

Learn more about Small Cell Lung Cancer

Care guides

Symptoms and treatments

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.