Mitotic inhibitors
What are Mitotic inhibitors?
Mitotic inhibitors are drugs derived from natural plant sources. They inhibit cell division or mitosis, where a single cell divides into two genetically identical daughter cells. Mitotic inhibitors bind to tubulin and inhibit its polymerization into microtubules. Microtubules are structures responsible for pulling the cell apart when it divides. Mitotic inhibitors affect cancer cells more than normal cells because cancer cells divide (mitotic cell division) more rapidly therefore are more susceptible to mitotic inhibition.
Different mitotic inhibitors are used to treat particular types of cancers, such as leukemia, lymphoma, breast cancer, lung cancer and other types of cancers.
List of Mitotic inhibitors
Drug Name | Avg. Rating | Reviews |
---|---|---|
docetaxel systemic (Pro) Brand name: Taxotere |
16 reviews | |
eribulin systemic (Pro) Brand name: Halaven |
11 reviews | |
paclitaxel systemic (Pro) |
10 reviews | |
paclitaxel protein-bound systemic Brand name: Abraxane |
7 reviews | |
vincristine systemic (Pro) |
4 reviews | |
etoposide systemic (Pro) Brand names: Etopophos, Toposar |
2 reviews | |
estramustine systemic (Pro) Brand name: Emcyt |
1 review | |
vinorelbine systemic (Pro) Brand name: Navelbine | No reviews | |
vincristine liposome systemic Brand name: Marqibo | No reviews | |
vinblastine systemic (Pro) | No reviews | |
ixabepilone systemic (Pro) Brand name: Ixempra | No reviews | |
cabazitaxel systemic (Pro) Brand name: Jevtana | No reviews | |
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective). |
See also
Medical conditions treated or associated with mitotic inhibitors:
- Acute Lymphoblastic Leukemia
- Acute Lymphocytic Leukemia
- Acute Myeloid Leukemia
- Anaplastic Oligodendroglioma
- Breast Cancer
- Breast Cancer, Adjuvant
- Breast Cancer, Metastatic
- Cancer
- Choriocarcinoma
- Diffuse Large B-Cell Lymphoma
- Gastric Cancer
- Head and Neck Cancer
- Histiocytosis
- Hodgkin's Lymphoma
- Kaposi's Sarcoma
- Liposarcoma
- Lymphoma
- Multiple Myeloma
- Mycosis Fungoides
- Nasopharyngeal Carcinoma
- Neuroblastoma
- Non Small Cell Lung Cancer
- Non-Hodgkin's Lymphoma
- Ovarian Cancer
- Pancreatic Cancer
- Prostate Cancer
- Rhabdomyosarcoma
- Small Cell Lung Cancer
- Testicular Cancer
- Wilms' Tumor
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.