Alkylating agents are a class of chemotherapy drugs that bind to DNA and prevent proper DNA replication. They have chemical groups that can form permanent covalent bonds with nucleophilic substances in the DNA.
Alkylating agents are used as part of chemotherapy in different types of cancers.
Subscribe to receive email notifications whenever new articles are published.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex® (updated May 1st, 2017), Cerner Multum™ (updated May 3rd, 2017), Wolters Kluwer™ (updated May 2nd, 2017) and others. To view content sources and attributions, please refer to our editorial policy.