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Medications for Diffuse Large B-Cell Lymphoma

Other names: DLBCL

About Diffuse Large B-Cell Lymphoma: 

Diffuse Large B-Cell Lymphoma (DLBCL) is the most common subtype of non-Hodgkin's lymphoma. Lymphoma is a cancer of the lymphatic system which occurs when a developing white cell (lymphocyte) goes through an abnormal change, multiplies and accumulates in various parts of the body.

DLBCL is a fast growing lymphoma that develops from the mature B cells and can arise in the lymph nodes or in other organs or tissues. Some of the rarer DLBCL have their own classification but the most common subtype is known as 'not otherwise specified'.

General symptoms of DLBCL are fevers, night sweats and weight loss. Another symptom is painless and fast growing lymph nodes, these swelling can also occur in the abdomen, liver, lungs, skin and other areas of the body.

Drugs Used to Treat Diffuse Large B-Cell Lymphoma

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
cyclophosphamide D N Add review Rate

Generic name: cyclophosphamide systemic

Drug class: alkylating agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

doxorubicin D N Add review Rate

Generic name: doxorubicin systemic

Brand name:  Adriamycin

Drug class: antibiotics/antineoplastics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

rituximab C N Add review Rate

Generic name: rituximab systemic

Brand name:  Rituxan

Drug class: antirheumatics, CD20 monoclonal antibodies

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

vincristine D N Add review Rate

Generic name: vincristine systemic

Brand names:  Oncovin, Vincasar PFS

Drug class: mitotic inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

prednisone C N Add review Rate

Generic name: prednisone systemic

Drug class: glucocorticoids

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

axicabtagene ciloleucel U Add review Rate

Generic name: axicabtagene ciloleucel systemic

Drug class: miscellaneous antineoplastics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts

hyaluronidase / rituximab N Add review Rate

Generic name: hyaluronidase / rituximab systemic

Brand name:  Rituxan Hycela

Drug class: CD20 monoclonal antibodies

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts

Rituxan C N Add review Rate

Generic name: rituximab systemic

Drug class: antirheumatics, CD20 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Adriamycin D N Add review Rate

Generic name: doxorubicin systemic

Drug class: antibiotics/antineoplastics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Oncovin D N Add review Rate

Generic name: vincristine systemic

Drug class: mitotic inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Rituxan Hycela N Add review Rate

Generic name: hyaluronidase / rituximab systemic

Drug class: CD20 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Vincasar PFS D N Add review Rate

Generic name: vincristine systemic

Drug class: mitotic inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Kymriah U Add review Rate

Generic name: tisagenlecleucel systemic

Drug class: miscellaneous antineoplastics

For consumers: dosage, interactions, side effects

tisagenlecleucel U Add review Rate

Generic name: tisagenlecleucel systemic

Brand name:  Kymriah

Drug class: miscellaneous antineoplastics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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