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Medications for Chronic Myelogenous Leukemia

Other names: Cancer, Chronic Myelogenous Leukemia; Chronic Granulocytic Leukemia; CML; Leukemia, Chronic Granulocytic

About Chronic Myelogenous Leukemia:  Chronic Myelogenous Leukemia is cancer that starts inside bone marrow. Chronic Myelogenous Leukemia causes an uncontrolled growth of¬†immature cells that make a certain type of white blood cell called myeloid cells. The diseased cells build up in the bone marrow and blood.

Drugs Used to Treat Chronic Myelogenous Leukemia

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Gleevec D N 21 reviews
9.0

Generic name: imatinib systemic

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Tasigna D N 19 reviews
7.0

Generic name: nilotinib systemic

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Sprycel D N 12 reviews
8.0

Generic name: dasatinib systemic

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
imatinib D N 25 reviews
9.0

Generic name: imatinib systemic

Brand name:  Gleevec

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Hydrea D N 1 review
9.0

Generic name: hydroxyurea systemic

Drug class: antimetabolites

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
hydroxyurea D N 1 review
8.0

Generic name: hydroxyurea systemic

Brand name:  Hydrea

Drug class: antimetabolites

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
nilotinib D N 26 reviews
8.0

Generic name: nilotinib systemic

Brand name:  Tasigna

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Bosulif D N 4 reviews
7.0

Generic name: bosutinib systemic

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
dasatinib D N 15 reviews
8.0

Generic name: dasatinib systemic

Brand name:  Sprycel

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Iclusig D N 1 review
5.0

Generic name: ponatinib systemic

Drug class: multikinase inhibitors, BCR-ABL tyrosine kinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
anagrelide Off Label C N Add review Rate

Generic name: anagrelide systemic

Brand name:  Agrylin

Drug class: miscellaneous uncategorized agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
cyclophosphamide D N 2 reviews
10

Generic name: cyclophosphamide systemic

Drug class: alkylating agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
ponatinib D N 1 review
5.0

Generic name: ponatinib systemic

Brand name:  Iclusig

Drug class: multikinase inhibitors, BCR-ABL tyrosine kinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Synribo D N Add review Rate

Generic name: omacetaxine systemic

Drug class: miscellaneous antineoplastics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Agrylin Off Label C N Add review Rate

Generic name: anagrelide systemic

Drug class: miscellaneous uncategorized agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
bosutinib D N 4 reviews
7.0

Generic name: bosutinib systemic

Brand name:  Bosulif

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Myleran D N 1 review
10

Generic name: busulfan systemic

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
busulfan D N 1 review
10

Generic name: busulfan systemic

Brand names:  Myleran, Busulfex

Drug class: alkylating agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Busulfex D N Add review Rate

Generic name: busulfan systemic

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
cytarabine D N Add review Rate

Generic name: cytarabine systemic

Drug class: antimetabolites

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
fludarabine Off Label D N Add review Rate

Generic name: fludarabine systemic

Drug class: antimetabolites

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
omacetaxine D N Add review Rate

Generic name: omacetaxine systemic

Brand name:  Synribo

Drug class: miscellaneous antineoplastics

For consumers: dosage, interactions,

For professionals: AHFS DI Monograph

 
peginterferon alfa-2b C N Add review Rate

Generic name: peginterferon alfa-2b systemic

Drug class: antineoplastic interferons, antiviral interferons

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts

 

Learn more about Chronic Myelogenous Leukemia

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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