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Medications for Chronic Myelogenous Leukemia

Other names: Cancer, Chronic Myelogenous Leukemia; Chronic Granulocytic Leukemia; CML; Leukemia, Chronic Granulocytic

About Chronic Myelogenous Leukemia

Chronic Myelogenous Leukemia is cancer that starts inside bone marrow. Chronic Myelogenous Leukemia causes an uncontrolled growth of immature cells that make a certain type of white blood cell called myeloid cells. The diseased cells build up in the bone marrow and blood.

Drugs used to treat Chronic Myelogenous Leukemia

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Gleevec 8.6 22 reviews
Rx D N

Generic name: imatinib systemic

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Sprycel 8.1 13 reviews
Rx D N

Generic name: dasatinib systemic

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Tasigna 7.8 28 reviews
Rx D N

Generic name: nilotinib systemic

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

imatinib 8.8 26 reviews
Rx D N

Generic name: imatinib systemic

Brand name:  Gleevec

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

dasatinib 8.1 17 reviews
Rx D N

Generic name: dasatinib systemic

Brand name:  Sprycel

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Iclusig 5.0 1 review
Rx D N

Generic name: ponatinib systemic

Drug class: multikinase inhibitors, BCR-ABL tyrosine kinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ponatinib 5.0 1 review
Rx D N

Generic name: ponatinib systemic

Brand name:  Iclusig

Drug class: multikinase inhibitors, BCR-ABL tyrosine kinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Bosulif 7.0 5 reviews
Rx D N

Generic name: bosutinib systemic

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

hydroxyurea 9.5 2 reviews
Rx D N

Generic name: hydroxyurea systemic

Brand name:  Hydrea

Drug class: antimetabolites

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Hydrea 10 1 review
Rx D N

Generic name: hydroxyurea systemic

Drug class: antimetabolites

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

nilotinib 8.1 37 reviews
Rx D N

Generic name: nilotinib systemic

Brand name:  Tasigna

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

anagrelide Off-label Rate Add review
Rx C N

Generic name: anagrelide systemic

Brand name:  Agrylin

Drug class: miscellaneous coagulation modifiers

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

cyclophosphamide 10 2 reviews
Rx D N

Generic name: cyclophosphamide systemic

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

bosutinib 7.0 5 reviews
Rx D N

Generic name: bosutinib systemic

Brand name:  Bosulif

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Synribo Rate Add review
Rx D N

Generic name: omacetaxine systemic

Drug class: miscellaneous antineoplastics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Agrylin Off-label Rate Add review
Rx C N

Generic name: anagrelide systemic

Drug class: miscellaneous coagulation modifiers

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

Myleran 10 1 review
Rx D N

Generic name: busulfan systemic

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

busulfan 10 1 review
Rx D N

Generic name: busulfan systemic

Brand names:  Myleran, Busulfex

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Busulfex Rate Add review
Rx D N

Generic name: busulfan systemic

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

omacetaxine Rate Add review
Rx D N

Generic name: omacetaxine systemic

Brand name:  Synribo

Drug class: miscellaneous antineoplastics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

cytarabine Rate Add review
Rx D N

Generic name: cytarabine systemic

Drug class: antimetabolites

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

fludarabine Off-label Rate Add review
Rx D N

Generic name: fludarabine systemic

Drug class: antimetabolites

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

peginterferon alfa-2b Rate Add review
Rx C N

Generic name: peginterferon alfa-2b systemic

Drug class: antineoplastic interferons, antiviral interferons

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts

Learn more about Chronic Myelogenous Leukemia

IBM Watson Micromedex

Mayo Clinic Reference

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.