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VEGF/VEGFR inhibitors

What are VEGF/VEGFR inhibitors?

Vascular endothelial growth factor (VEGF)/ vascular endothelial growth factor receptor (VEGFR) inhibitors are agents that inhibit the activity of VEGF and VEGFR. VEGR and VEGFR (a tyrosine kinase receptor) signaling modulates angiogenesis, which involves making of new blood vessels from existing blood vessels.

Abnormal angiogenesis is known to occur in cancer, degenerative eye conditions and other conditions that involve inflammation. Specific monoclonal antibodies can be used as VEGF inhibitors and particular tyrosine kinase inhibitors are used as VEGFR inhibitors.

Vascular endothelial growth factor (VEGF)/ vascular endothelial growth factor receptor (VEGFR) inhibitors are used to treat various types of cancers.

List of VEGF/VEGFR inhibitors:

View by  Brand | Generic
Drug Name Avg. Rating Reviews
Votrient (Pro)
Generic name: pazopanib
8.2
81 reviews
Sutent (Pro)
Generic name: sunitinib
7.1
30 reviews
Avastin (Pro)
Generic name: bevacizumab
7.9
27 reviews
Nexavar (Pro)
Generic name: sorafenib
5.4
14 reviews
Stivarga (Pro)
Generic name: regorafenib
2.5
7 reviews
Cabometyx (Pro)
Generic name: cabozantinib
8.5
7 reviews
Lenvima (Pro)
Generic name: lenvatinib
7.5
2 reviews
Iclusig (Pro)
Generic name: ponatinib
3.0
2 reviews
Cometriq (Pro)
Generic name: cabozantinib
1.0
2 reviews
Zaltrap (Pro)
Generic name: ziv-aflibercept
10
1 review
Inlyta (Pro)
Generic name: axitinib
7.5
1 review
Zirabev (Pro)
Generic name: bevacizumab
No reviews
Mvasi (Pro)
Generic name: bevacizumab
No reviews
Fotivda (Pro)
Generic name: tivozanib
No reviews
Cyramza (Pro)
Generic name: ramucirumab
No reviews
Caprelsa (Pro)
Generic name: vandetanib
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.