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Medications for Renal Cell Carcinoma

Other names: Adenocarcinoma of renal cells; Cancer, Hypernephroma; Cancer, Kidney; Cancer, Renal; Cancer, Renal Cell Carcinoma; Hypernephroma; Kidney Cancer; Renal Cancer

About Renal Cell Carcinoma

Renal cell carcinoma, a form of kidney cancer that involves cancerous changes in the cells of the renal tubule, is the most common type of kidney cancer in adults

Drugs used to treat Renal Cell Carcinoma

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Sutent 7.5 27 reviews
Rx D N

Generic name: sunitinib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Votrient 8.2 56 reviews
Rx D N

Generic name: pazopanib systemic

Drug class: VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Inlyta 9.0 1 review
Rx D N

Generic name: axitinib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Afinitor 5.5 2 reviews
Rx D N

Generic name: everolimus systemic

Drug class: mTOR inhibitors, selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

pazopanib 8.3 62 reviews
Rx D N

Generic name: pazopanib systemic

Brand name:  Votrient

Drug class: VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

sunitinib 7.3 31 reviews
Rx D N

Generic name: sunitinib systemic

Brand name:  Sutent

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Cabometyx 8.6 5 reviews
Rx D N

Generic name: cabozantinib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

nivolumab 5.8 10 reviews
Rx N

Generic name: nivolumab systemic

Brand name:  Opdivo

Drug class: anti-PD-1 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

axitinib 9.0 2 reviews
Rx D N

Generic name: axitinib systemic

Brand name:  Inlyta

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Opdivo 5.2 5 reviews
Rx N

Generic name: nivolumab systemic

Drug class: anti-PD-1 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

everolimus 5.5 2 reviews
Rx D N

Generic name: everolimus systemic

Brand name:  Afinitor

Drug class: mTOR inhibitors, selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

cabozantinib 6.7 9 reviews
Rx D N

Generic name: cabozantinib systemic

Brand name:  Cabometyx

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Lenvima 6.0 1 review
Rx N

Generic name: lenvatinib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

lenvatinib 6.0 1 review
Rx N

Generic name: lenvatinib systemic

Brand name:  Lenvima

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Nexavar 10 2 reviews
Rx D N

Generic name: sorafenib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

avelumab 9.0 1 review
Rx N

Generic name: avelumab systemic

Brand name:  Bavencio

Drug class: anti-PD-1 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Bavencio Rate Add review
Rx N

Generic name: avelumab systemic

Drug class: anti-PD-1 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ipilimumab Rate Add review
Rx C N

Generic name: ipilimumab systemic

Brand name:  Yervoy

Drug class: anti-CTLA-4 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Yervoy Rate Add review
Rx C N

Generic name: ipilimumab systemic

Drug class: anti-CTLA-4 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Avastin 8.0 1 review
Rx C N

Generic name: bevacizumab systemic

Drug class: VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Torisel 9.5 2 reviews
Rx D N

Generic name: temsirolimus systemic

Drug class: mTOR inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Proleukin 10 1 review
Rx C N

Generic name: aldesleukin systemic

Drug class: miscellaneous antineoplastics, interleukins

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Keytruda Rate Add review
Rx D N

Generic name: pembrolizumab systemic

Drug class: anti-PD-1 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

sorafenib 10 2 reviews
Rx D N

Generic name: sorafenib systemic

Brand name:  Nexavar

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

medroxyprogesterone Off-label 7.0 1 review
Rx X N

Generic name: medroxyprogesterone systemic

Drug class: hormones/antineoplastics, contraceptives, progestins

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

Topics under Renal Cell Carcinoma

Learn more about Renal Cell Carcinoma

IBM Watson Micromedex

Symptoms and treatments

Mayo Clinic Reference

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.