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Anti-CTLA-4 monoclonal antibodies

What are Anti-CTLA-4 monoclonal antibodies?

Monoclonal antibodies used in immunotherapy are produced artificially from a cell clone therefore consist of a single type of immunoglobulin. They are targeted towards specific antigens and bind to the antigens to form a complex. The complex can be recognized and destroyed by phagocytes or used for other diagnostic purposes. Anti-CTLA-4 monoclonal antibodies are directed to the inhibitory receptor CD152 (CTLA-4). They may be use to treat certain types of melanoma.

List of Anti-CTLA-4 monoclonal antibodies:

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Yervoy (Pro, More...)
generic name: ipilimumab
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Medical conditions associated with anti-CTLA-4 monoclonal antibodies: