Antineoplastics or anticancer drugs affect the process of cell division i.e. are antiproliferative. They damage the DNA and initiate apoptosis, preventing the development and spread of neoplastic cells.
They also affect rapidly dividing normal cells, therefore are likely to suppress the bone marrow, suppress growth, impair healing, cause sterility and cause hair loss.
Please refer to the drug classes listed below for further information.
- alkylating agents
- anti-CTLA-4 monoclonal antibodies
- anti-PD-1 monoclonal antibodies
- antineoplastic detoxifying agents
- antineoplastic interferons
- BCR-ABL tyrosine kinase inhibitors
- CD20 monoclonal antibodies
- CD30 monoclonal antibodies
- CD33 monoclonal antibodies
- CD38 monoclonal antibodies
- CD52 monoclonal antibodies
- EGFR inhibitors
- hedgehog pathway inhibitors
- HER2 inhibitors
- histone deacetylase inhibitors
- miscellaneous antineoplastics
- mitotic inhibitors
- mTOR inhibitors
- multikinase inhibitors
- proteasome inhibitors
- VEGF/VEGFR inhibitors