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Antineoplastic combinations

Medically reviewed by C. Fookes, BPharm Last updated on Jun 6, 2019.

Other names: anticancer combinations, antitumor combinations, chemotherapy combinations

What are Antineoplastic combinations?

An antineoplastic drug is one that is used to prevent or treat the growth and spread of tumors or malignant cells; in other words, cancer.

Combinations of antineoplastic drugs are usually more effective than single agents alone because each agent has a different way of targeting the way cancer grows. Two or more drugs, each with a different method of action, may be used in an antineoplastic combination.

Research has shown that combination treatment increases tumor response (tumor shrinkage), survival rates, and prolongs the time it takes before cancer progresses. However, the risk of side effects, such as nausea and vomiting, hair loss, and decreased white cell counts, is significantly increased. Combination treatment may also have a bigger negative impact on other psychological and social factors that contribute to a sense of quality of life. Trials have not yet shown if sequential treatment with different single agents is as effective or more effective than combination treatment.

The actual agents that make up the antineoplastic combination vary depending on tumor or cancer type; patient age and co-morbid medical conditions; previous cancer treatment history; local hospital protocols or guideline recommendations; cost and availability of each individual agent.

List of Antineoplastic combinations:

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Drug Name Reviews Avg. Ratings
Kisqali Femara Co-Pack (Pro)
Generic name: letrozole / ribociclib
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Lonsurf (Pro)
Generic name: tipiracil / trifluridine
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Vyxeos (Pro)
Generic name: cytarabine liposomal / daunorubicin liposomal
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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

See Also

Medical conditions associated with antineoplastic combinations:

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