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Kisqali Femara Co-Pack 200 mg-2.5 mg Dose

Generic Name: letrozole and ribociclib (LET roe zol and RYE boe SYE klib)
Brand Name: Kisqali Femara Co-Pack 200 mg-2.5 mg Dose, Kisqali Femara Co-Pack 400 mg-2.5 mg Dose, Kisqali Femara Co-Pack 600 mg-2.5 mg Dose

Medically reviewed by Drugs.com on Mar 28, 2019 – Written by Cerner Multum

What is Kisqali Femara Co-Pack 200 mg-2.5 mg Dose?

Letrozole lowers estrogen levels, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.

Ribociclib interferes with the growth and spread of cancer cells in the body.

Kisqali Femara Co-Pack 200 mg-2.5 mg Dose are used together in combination to treat HR-positive, HER2-negative breast cancer in women.

Kisqali Femara Co-Pack 200 mg-2.5 mg Dose is used when the cancer has spread to other parts of the body (metastatic).

Kisqali Femara Co-Pack 200 mg-2.5 mg Dose are two different medicines that are packaged together. Letrozole tablets are yellow and ribociclib tablets are violet.

Kisqali Femara Co-Pack 200 mg-2.5 mg Dose may also be used for purposes not listed in this medication guide.

Important Information

This medicine can cause a serious heart rhythm problem. Call your doctor at once if you have fast or pounding heartbeats and severe dizziness.

Kisqali Femara Co-Pack 200 mg-2.5 mg Dose may also affect your liver or blood cells. Tell your doctor if you have right-sided stomach pain, tiredness, easy bruising or bleeding, dark urine, and jaundice (yellowing of the skin or eyes).

You will need frequent medical tests while taking Kisqali Femara Co-Pack 200 mg-2.5 mg Dose. Your cancer treatments may be delayed based on the results of these tests.

Other serious side effects of this medicine include fever, chills, and flu symptoms.

Before taking this medicine

You should not use Kisqali Femara Co-Pack 200 mg-2.5 mg Dose if you are allergic to letrozole (Femara) or ribociclib (Kisqali).

Your doctor will perform medical tests to make sure you do not have conditions that would prevent you from safely using this medicine.

Tell your doctor if you have any signs of infection, such as fever or chills, or if you have ever had:

  • heart disease, heart failure;

  • a heart attack;

  • heart rhythm problems, including slow heartbeats;

  • long QT syndrome;

  • low levels of calcium, phosphorus, potassium, or magnesium in your blood; or

  • liver or kidney disease.

If you have not gone through menopause, you may need an additional hormonal medication while taking Kisqali Femara Co-Pack 200 mg-2.5 mg Dose. Tell your doctor if you have begun having symptoms of menopause such as irregular menstrual periods, hot flashes, night sweats, sleep problems, or vaginal dryness.

You may need to have a negative pregnancy test before starting this treatment.

Kisqali Femara Co-Pack 200 mg-2.5 mg Dose may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 weeks after your last dose. Tell your doctor right away if you become pregnant.

This medicine may affect fertility (ability to have children) in both men and women. However, it is important for women to use birth control to prevent pregnancy because Kisqali Femara Co-Pack 200 mg-2.5 mg Dose may harm the baby if a pregnancy does occur.

You should not breast-feed while using this medicine and for at least 3 weeks after your last dose.

How should I take Kisqali Femara Co-Pack 200 mg-2.5 mg Dose?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

It is best to take this medicine in the morning, but take it at the same time each day. You may take Kisqali Femara Co-Pack 200 mg-2.5 mg Dose with or without food.

Kisqali Femara Co-Pack 200 mg-2.5 mg Dose is given in a 28-day treatment cycle. On days 1 through 21, you will take both ribociclib and letrozole together at the same time each day. During the last 7 days you will take only letrozole each day.

Your doctor may occasionally change the number of tablets in your dose. Follow all dosing instructions very carefully.

Swallow each tablet whole and do not crush, chew, or break it. Do not take any tablet that is broken or cracked.

If you vomit shortly after taking a tablet, do not take another dose. Wait until your next scheduled dose time to take the medicine again.

This medicine can cause a serious heart rhythm problem. Call your doctor at once if you have a fast or pounding heartbeats and severe dizziness.

You will need frequent medical tests while taking Kisqali Femara Co-Pack 200 mg-2.5 mg Dose. Your cancer treatments may be delayed based on the results of these tests.

Do not change your dose or stop taking this medicine without your doctor's advice.

Store each medicine in its original container at room temperature, away from moisture and heat.

What happens if I miss a dose?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Kisqali Femara Co-Pack 200 mg-2.5 mg Dose?

Grapefruit may interact with Kisqali Femara Co-Pack 200 mg-2.5 mg Dose and lead to unwanted side effects. Avoid the use of grapefruit products.

Kisqali Femara Co-Pack 200 mg-2.5 mg Dose side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);

  • liver problems--loss of appetite, right-sided stomach pain, tiredness, easy bruising or bleeding, dark urine, jaundice (yellowing of the skin or eyes); or

  • low white blood cell counts--fever, mouth sores, skin sores, sore throat, cough, trouble breathing.

Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Kisqali Femara Co-Pack 200 mg-2.5 mg Dose?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Kisqali Femara Co-Pack 200 mg-2.5 mg Dose can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.

Many drugs can affect Kisqali Femara Co-Pack 200 mg-2.5 mg Dose. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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