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CD52 monoclonal antibodies

What are CD52 monoclonal antibodies?

Monoclonal antibodies used in immunotherapy are produced artificially from a cell clone therefore consist of a single type of immunoglobulin. They are targeted towards specific antigens and bind to the antigens to form a complex. The complex can be recognized and destroyed by phagocytes or used for other diagnostic purposes.

Natural antibodies are proteins made by the B-lymphocytes in response to antigens. Each B-cell makes only one type of antibody. For therapeutic purposes a significant amount of a particular antibody is needed. These are obtained from a culture that gives a one type of antibody, which are called monoclonal antibodies.

CD52 antigens are present on lymphocytes. CD52 monoclonal antibodies bind to CD52 antigens and bring about complement and antibody-dependent cell-mediated cytotoxicity. CD52 monoclonal antibodies are used to treat patients with B-cell chronic lymphocytic leukemia (B-CLL).

List of CD52 monoclonal antibodies:

View by  Brand | Generic
Drug Name Reviews Avg. Ratings
Lemtrada (Pro)
Generic name: alemtuzumab
13 reviews
6.6
Campath (Pro)
Generic name: alemtuzumab
0 reviewsAdd rating
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

See Also

Medical conditions associated with CD52 monoclonal antibodies: