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Medications for Chronic Lymphocytic Leukemia

Other names: Cancer, Chronic Lymphocytic Leukemia; CLL; Leukemia, Chronic Lymphocytic

About Chronic Lymphocytic Leukemia:  Chronic lymphocytic leukemia (CLL) is cancer in your blood and bone marrow. The bone marrow makes damaged lymphocytes and the body has trouble fighting infections.

See also: sub-topics

Drugs Used to Treat Chronic Lymphocytic Leukemia

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Imbruvica D N 18 reviews
5.8

Generic name: ibrutinib systemic

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Rituxan C N 2 reviews
9.0

Generic name: rituximab systemic

Drug class: antirheumatics, CD20 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

ibrutinib D N 25 reviews
6.3

Generic name: ibrutinib systemic

Brand name:  Imbruvica

Drug class: multikinase inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

rituximab C N 6 reviews
9.4

Generic name: rituximab systemic

Brand name:  Rituxan

Drug class: antirheumatics, CD20 monoclonal antibodies

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Leukeran D N 2 reviews
9.5

Generic name: chlorambucil systemic

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Arzerra C N Add review
9.0

Generic name: ofatumumab systemic

Drug class: CD20 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

fludarabine D N 1 review
6.0

Generic name: fludarabine systemic

Drug class: antimetabolites

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

cyclophosphamide D N Add review
0.0

Generic name: cyclophosphamide systemic

Drug class: alkylating agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

chlorambucil D N 2 reviews
9.5

Generic name: chlorambucil systemic

Brand name:  Leukeran

Drug class: alkylating agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Treanda D N Add review
10

Generic name: bendamustine systemic

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

bendamustine D N 1 review
10

Generic name: bendamustine systemic

Brand names:  Treanda, Bendeka, Belrapzo

Drug class: alkylating agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Gazyva C N Add review
10

Generic name: obinutuzumab systemic

Drug class: CD20 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Campath C N Add review
0.0

Generic name: alemtuzumab systemic

Drug class: CD52 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

idelalisib D N X Add review
0.0

Generic name: idelalisib systemic

Brand name:  Zydelig

Drug class: PI3K inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

immune globulin intravenous C N Add review
0.0

Generic name: immune globulin intravenous systemic

Brand names:  Octagam, Carimune, Gammagard S / D, Flebogamma, Gamimune, Gammaplex, Gammar-P I.V., Iveegam En, Polygam S / D, Sandoglobulin, Gamimune N 5%, Panglobulin NF …show all

Drug class: immune globulins

For consumers: dosage, interactions,

Venclexta N Add review
0.0

Generic name: venetoclax systemic

Drug class: miscellaneous antineoplastics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Octagam C N Add review
0.0

Generic name: immune globulin intravenous systemic

Drug class: immune globulins

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

obinutuzumab C N Add review
10

Generic name: obinutuzumab systemic

Brand name:  Gazyva

Drug class: CD20 monoclonal antibodies

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

venetoclax N Add review
0.0

Generic name: venetoclax systemic

Brand name:  Venclexta

Drug class: miscellaneous antineoplastics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Zydelig D N X Add review
0.0

Generic name: idelalisib systemic

Drug class: PI3K inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Bendeka D N Add review
0.0

Generic name: bendamustine systemic

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

alemtuzumab C N Add review
0.0

Generic name: alemtuzumab systemic

Brand name:  Campath

Drug class: CD52 monoclonal antibodies

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

ofatumumab C N Add review
9.0

Generic name: ofatumumab systemic

Brand name:  Arzerra

Drug class: CD20 monoclonal antibodies

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Carimune C N Add review
0.0

Generic name: immune globulin intravenous systemic

Drug class: immune globulins

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Gammagard S / D C N Add review
0.0

Generic name: immune globulin intravenous systemic

Drug class: immune globulins

For consumers: dosage, interactions, side effects

Topics under Chronic Lymphocytic Leukemia

Learn more about Chronic Lymphocytic Leukemia

IBM Watson Micromedex

Symptoms and treatments

Mayo Clinic Reference

ICD-10 CM Clinical Codes (External)

Legend

Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Off Label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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