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Medications for Chronic Lymphocytic Leukemia

Other names: Cancer, Chronic Lymphocytic Leukemia; CLL; Leukemia, Chronic Lymphocytic

Chronic lymphocytic leukemia (CLL) is cancer in your blood and bone marrow. The bone marrow makes damaged lymphocytes and the body has trouble fighting infections.

Drugs used to treat Chronic Lymphocytic Leukemia

The following list of medications are in some way related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Imbruvica 5.6 33 reviews
Rx D N

Generic name: ibrutinib systemic

Drug class: BTK inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ibrutinib 6.1 44 reviews
Rx D N

Generic name: ibrutinib systemic

Brand name:  Imbruvica

Drug class: BTK inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

rituximab 9.4 6 reviews
Rx C N

Generic name: rituximab systemic

Brand names:  Rituxan, Truxima, Riabni, Ruxience …show all

Drug class: antirheumatics, CD20 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Rituxan 9.0 2 reviews
Rx C N

Generic name: rituximab systemic

Drug class: antirheumatics, CD20 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Leukeran 9.5 2 reviews
Rx D N

Generic name: chlorambucil systemic

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Gazyva 0.0 1 review
Rx C N

Generic name: obinutuzumab systemic

Drug class: CD20 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

chlorambucil 9.5 2 reviews
Rx D N

Generic name: chlorambucil systemic

Brand name:  Leukeran

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Calquence 10 1 review
Rx N

Generic name: acalabrutinib systemic

Drug class: BTK inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

obinutuzumab 0.0 1 review
Rx C N

Generic name: obinutuzumab systemic

Brand name:  Gazyva

Drug class: CD20 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

acalabrutinib 10 2 reviews
Rx N

Generic name: acalabrutinib systemic

Brand name:  Calquence

Drug class: BTK inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

idelalisib Rate Add review
Rx D N X

Generic name: idelalisib systemic

Brand name:  Zydelig

Drug class: PI3K inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Zydelig Rate Add review
Rx D N X

Generic name: idelalisib systemic

Drug class: PI3K inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Truxima Rate Add review
Rx C N

Generic name: rituximab systemic

Drug class: CD20 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ofatumumab Rate Add review
Rx C N

Generic name: ofatumumab systemic

Brand name:  Arzerra

Drug class: CD20 monoclonal antibodies, selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

venetoclax 9.0 1 review
Rx N

Generic name: venetoclax systemic

Brand name:  Venclexta

Drug class: miscellaneous antineoplastics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Venclexta 9.0 1 review
Rx N

Generic name: venetoclax systemic

Drug class: miscellaneous antineoplastics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Arzerra Rate Add review
Rx C N

Generic name: ofatumumab systemic

Drug class: CD20 monoclonal antibodies, selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

cyclophosphamide Rate Add review
Rx D N

Generic name: cyclophosphamide systemic

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

fludarabine 6.0 1 review
Rx D N

Generic name: fludarabine systemic

Drug class: antimetabolites

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

bendamustine 10 1 review
Rx D N

Generic name: bendamustine systemic

Brand names:  Treanda, Bendeka, Belrapzo

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Treanda Rate Add review
Rx D N

Generic name: bendamustine systemic

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Campath Rate Add review
Rx C N

Generic name: alemtuzumab systemic

Drug class: CD52 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

immune globulin intravenous Rate Add review
Rx C N

Generic name: immune globulin intravenous systemic

Brand name:  Gammagard S/D

Drug class: immune globulins

For consumers: dosage, interactions, side effects

alemtuzumab Rate Add review
Rx C N

Generic name: alemtuzumab systemic

Brand name:  Campath

Drug class: CD52 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Riabni Rate Add review
Rx C N

Generic name: rituximab systemic

Drug class: CD20 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Learn more about Chronic Lymphocytic Leukemia

Care guides

Symptoms and treatments

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.