Obinutuzumab for Chronic Lymphocytic Leukemia User Reviews

• Tom...
• October 25, 2024

Obinutuzumab "I had 8 infusions. I did very good, usually around 6 hrs of drip. Went to the gym after 3 of them. Ran a 9-mile race the day after. One of them was just very tired the next day. I now take Calquence. White blood cells went from 45,000 to 5,000. So happy. It's been 2 years now. Life is great. Love the ones you love, and be kind to all."

• wil...
• Taken for 1 to 6 months
• January 15, 2025

Obinutuzumab "Received Gazyva-Venetoclax combo in 2020-2021 to treat CLL/SLL, got a complete response and am still cruising along in Jan. 2025 with no meds; I am starting to see lymph node enlargement and will follow up as scheduled in March. I really liked a treatment with an endpoint. No problems with the pre-medications or infusions, and though the combo sent me into neutropenia in the middle of the pandemic, I didn't catch COVID until they had Paxlovid. The combo did require frequent bloodwork, especially with the neutropenia. I am hoping to use the same combo when the time comes for retreatment! The alternative, Imbruvica, is not as easy on folks with cardiac symptoms as this treatment."

• Gig...
• Taken for 1 to 6 months
• December 31, 2024

"I took obinutuzumab in combination with venetoclax as part of a study at a research institution. I was supposed to take obin at one-week intervals for three weeks, then monthly for several more. Venetoclax was to start after a month. The first dose of obin was a ten percent dose to check for reactions. I had several different reactions, and they learned I needed to have a steroid, antihistamine, anti-nausea drug, and Tylenol before each treatment. The second day when the rest of the dose was infused went well. The obin was a bit like dynamite fishing, it killed plenty of fish but sure messed up the environment. It lowered my red blood cells, platelets, and neutrophils a lot. I landed up in the ER after a blood transfusion that week, where they admitted me for three days and pumped me full of antibiotics. It lowered my platelets so much they couldn’t give me a second dose for over a month. After my second dose, I felt much better than before I started and had no further issues."

• Ano...
• Taken for 1 to 6 months
• May 31, 2025

Obinutuzumab "I had these infusions 5 years ago for initial treatment for SLL, had no problems with the actual infusions but developed neutropenia-Venetoclax may have also been partially responsible for the neutropenia. I had several shots of Granix (?) and reduced Ven to 300 mg. Made it through to the 1-year mark on Ven, total of 8 Gazyva infusions that lasted me till now-5 years. I begin my second treatment for SLL next month; doc says they typically use Ven only for second treatment, but my nodes are so full they're beginning to hurt to the touch. I'm planning to ask for at least 2-3 Gazyvas because I don't want TLS! Between Ven and Gazyva, lots of blood work needed-but it was worth it to have no meds these past 4 years!"

• Jud...
• Taken for 1 to 6 months
• September 27, 2024

Obinutuzumab "Began treatment January - June 2015. First day was rough due to an increase in blood pressure and a deluge of dead cancer cells. Going on ten years, and all CBCs are normal as of 10/2024."

• Hap...
• August 24, 2019

Obinutuzumab "I was very happy with the results. I was up to 83,000 white count, and after the first treatment, it was down to 5,300. After one month, it was still down. I go back in Sept. for my next blood test."