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Sunitinib Dosage

Medically reviewed by Drugs.com. Last updated on Aug 9, 2024.

Applies to the following strengths: 12.5 mg; 25 mg; 37.5 mg; 50 mg

Usual Adult Dose for Renal Cell Carcinoma

50 mg orally once daily on a schedule of 4 weeks on treatment followed by 2 weeks off

Comment: May be taken with or without food.

Uses:

Usual Adult Dose for Gastrointestinal Stromal Tumor

50 mg orally once daily on a schedule of 4 weeks on treatment followed by 2 weeks off

Comment: May be taken with or without food.

Uses:

Usual Adult Dose for Pancreatic Cancer

37.5 mg orally once daily

Comments:


Use: For the treatment of progressive, well-differentiated pancreatic neuroendocrine tumors (pNET) in patients with unresectable locally advanced or metastatic disease.

Renal Dose Adjustments

Liver Dose Adjustments

Dose Adjustments

Dose interruption and/or dose modification may be made in 12.5 mg increments or decrements based on individual safety and tolerability.


Concomitant Use With Strong CYP450 3A4 Inhibitors and Inducers:
Recommendations:

Left Ventricular Dysfunction:

Precautions

US BOXED WARNING:
Hepatotoxicity


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration Advice:


General:
Therapy should be initiated by a physician experienced in the administration of anti-cancer agents.

Monitoring:

Patient Advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.