User Reviews for Pazopanib
Also known as: Votrient
Pazopanib has an average rating of 8.2 out of 10 from a total of 89 ratings on Drugs.com. 76% of reviewers reported a positive experience, while 8% reported a negative experience.
|Renal Cell Carcinoma||66 reviews||19 medications|
|Soft Tissue Sarcoma||23 reviews||6 medications|
|Summary of Pazopanib reviews||8.2||89 reviews|
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Votrient (pazopanib) for Renal Cell Carcinoma: “Have been on Votrient now for over three years and am in remission. Side effects have included hand and foot pain (very slight now) and have experienced weight loss (from 180 lbs to around 130 lbs) over the last three years. As of this year, there have been no signs of liver problems but have had minor digestion issues. It appears that Votrient has been successful -unlike my experience with Sutent, Avastin, Xeloda and Affinitor. I had been diagnosed with stage IV renal cell carcinoma-sarcomatoid in 2008, and had the left kidney removed (and spleen due to a fall in the hospital). I have been on Votrient now for the better of three years, am still employed and fully functional. ”
Votrient (pazopanib) for Renal Cell Carcinoma: “I have taken Votrient since 9/2010, starting at 800 mg per day, but reducing dosage to 400 mg then 200 mg due to high liver enzyme counts. I started taking Votrient after my kidney was removed due to RCC, in addition I had three tumors in my legs, which is how I found out I had RCC. After taking Votrient and the kidney removal two of the tumors disappeared, one year later and after taking the drug for one year I had the third tumor removed by surgery which was reduced in size by 50%. Today my latest scans are showing no new cancer sites. Side effects have been minimal, diarrhea, and change in taste with higher dosages, plus sexy looking white hair! This medicine has allowed me to continue traveling, and enjoy life without any limits.”
Votrient (pazopanib) for Renal Cell Carcinoma: “I have been on Votrient since Jan 2010. Started with a right kidney in 1999. In 2009 my family doctor suggested that I have a pulmonary doctor run some CTs to see what he thought. After 8 months of CTs, I had to go and get a biopsy and it proved 2 clear and 2 renal cell carcinoma had appeared between my lungs. I checked a couple of oncologists in town. Been on the medicine since January 2010 and have little significant change. A little diarrhea once in a while and headaches, some dizziness on occasion but no significant change. Feel real good about the treatment. Would recommend it to anyone. ”
Votrient (pazopanib) for Renal Cell Carcinoma: “I have been taking 800mg of Votrient daily since March, 2012 to treat Renal Cell Carcinoma tumors which developed when the cancer spread from a large tumor on my right kidney. Votrient has been effective in stopping the growth of the tumors and shrinking a few. Side effects experienced: treatable elevated blood pressure and diarrhea.”
Votrient (pazopanib) for Soft Tissue Sarcoma: “I was diagnosed with 4 baseball sarcoma tumers in my liver July 15 2014. Did 6 weeks of GEMS/Taxol and after the scan showed two more tumors in the liver and four now in my lungs. My doctor put me on Votrent and scanned me once again after six weeks. All the tumors in my lungs have shrunk half their size and one tumer in the liver shrunk half it's size as well and all the others in the liver are dying from the inside out. Praise The LORD !”
Votrient (pazopanib) for Renal Cell Carcinoma: “On Votrient since 2010 after Sutent. Results were good. After six months - no sign of metastasis and have been in remission since 2012. Votient had the effect of high blood pressure which was mitigated by Procardia. As of late, have lost weight and am having some digestive issues.”
Votrient (pazopanib) for Renal Cell Carcinoma: “I started on Votrient May 4, 2013. I take it at bedtime, which has really helped. I took it for about 24 days back in December, during the day, and side effects were far worse. So far, the side effects are more tolerable than Sutent. I do have high blood pressure and low platelets, but doctor is doing labs weekly. Some days the side effects are worse than others. I went to 800 mg last week and have more fatigue. I pray it works for my lung tumors as I have heard it has for others.”
Frequently asked questions
- Does Votrient cure cancer or shrink tumors?
- How long does Votrient stay in your system?
- Is Votrient immunotherapy?
- Is Votrient a chemotherapy treatment?
Votrient (pazopanib) for Renal Cell Carcinoma: “I have been taking votriant since Fall 2015. Bilateral Renal cell carcinoma. Left total nephectomy and partial right. Small spot on liver at that time. Remaining tumors on the right. Due to surgery complications after right kidney surgery, sepsis, heart attack and stroke. I am now 59 yrs old. Votriant 800 mgs daily for about 5 weeks was rough...but I would do it again. Vomiting, diarrhea, high blood pressure, body and tired all the time. My hair has turned white, most people like my highlights! My oncologist has been wonderful and I have responded well to lower doses of Votrient which has helped my side effects. September 2016 I received great news! I am cancer free. Continue on maintenance dose right now of 200 mg 3xwk”
Votrient (pazopanib) for Renal Cell Carcinoma: “I was diagnosed with renal cell carcinoma May 2015. I had right kidney removed due to huge tumor. Cancer mets. to my lungs. Tried several treatments that did not work. Finally I was prescribed Votrient! It worked immediately. I have been using it for about 7 months. The only side affects I experienced was high blood pressure. I just had scan a week ago and tumors are still shrinking or have gone away. I will continue to pray to GOD for your positive progress as well as mine. Stay positive and know that you will beat it!”
Votrient (pazopanib) for Renal Cell Carcinoma: “Began 800mg in May 2014; 10 months into treatment. No new mets at this time. High blood pressure began three weeks into treatment, a good sign in that it demonstrates the drug is working well. Hand foot syndrome, initially intense pain , but now under control. Weight loss due to loss of taste and appetite, a nutritionist can help. White hair. This is considered the least toxic targeted therapy drug for mRCC, do all you can to stay with it. If it is working for the first year you may continue to get excellent results for years to come. This is currently considered the first line therapy for mRCC. Take at night to reduce the stomach discomfort.”
Votrient (pazopanib) for Renal Cell Carcinoma: “Votrient was effective in shrinking tumors in lungs and inhibiting progression of tumors in spine and brain; but I had to discontinue it due to elevated liver enzymes. This happened with an 800 mg dose and a reduced dose of 400 mg. Side effects experienced early in treatment included elevated blood pressure (treated) and fatigue (tolerable).”
Votrient (pazopanib) for Renal Cell Carcinoma: “50 Y.O. male, diagnosed Stage IV mRCC on 1 may 2014. Radical nephrectomy of right kidney June 2015. Tumour had invaded surrounding fat, IVC and adheared to bowel. Mets appeared in Jan 2015 (liver). Started 800mg Votrient feb 2015; side effects included, white hair, gastric issues, loss of taste, high BP otherwise felt ok. After 1 Month high liver enzymes forced me to stop. After 4 weeks off, recommenced 400mg of Votrient. Side effects not as severe but similar to 800mg dose. Required a week off Votrient recently due to a bout of pneumonia. Liver Mets have shrunk from 20mm to 7.5 mm since Jan, 400mg seems to be working, lets hope it stays that way.”
Votrient (pazopanib) for Soft Tissue Sarcoma: “I was diagnosed with stage 4 Leiomyosarcoma 7/16/2013. Tumors in my stomach, liver, and a few affected lymph nodes. Had surgery and removed 40% of my stomach on 8/30/13. Surgery was a success. I Underwent 4 1/2 months of chemo with minimal shrinkage to existing tumors but did stunt the growth of the tumors. At that point my tumors were considered inoperable. Started Votrient 2/14, just found out my tumors have shrunk enough on my liver to be operable. Liver Surgery scheduled 10/14. So happy, praying Votrient is our miracle. Good luck to others with my condition.”
Votrient (pazopanib) for Renal Cell Carcinoma: “Just started taking Votrient 09-15-11 for renal cell carcinoma stage4, cyst in my spine and leg, no side effects as of yet. Looking forward to a positive experience and good reports on the medicine. Wish me luck.”
Votrient (pazopanib) for Renal Cell Carcinoma: “My husband started Votrient 800mg about a week ago after surgery for a metastatic renal cancer. So far he is doing so well, taking it at night seems to be working. Some mornings he is a little spent but he does stay up late. I am praying for a good result - he has numerous teeny lung lesions and just a teeny area where the L kidney had been. He is 53 and otherwise in very good health.”
Votrient (pazopanib) for Renal Cell Carcinoma: “RCC detected May 2018. Left kidney removed 20 yrs ago, started Votrient 800 mg on June 1, 2018. First follow up PET scan will be August 30th, to see how it is doing. Most side effects, diarrhea most days, hair turning white, bruising easily, now feet are very tender, even thou I am following instructions on applying urea lotion on both feet and hands twice daily. Take the Votrient first thing out of bed in the AM, with hopes I flush out early enough to have an active life, although I am limited some days, but must always know where restrooms are. When I started the Votrient, I went directly to 800mg, and have stayed on it daily since, I feel that I must tough it out, and stay with it, to give it the best chance to work. Praying for good scan results. God Bless you folks that are in the same fight, stay on meds, stay as active as you can (I walk 20-30 minutes every day), and eat to keep weight up which will help with your strength. My prayers are with you.”
Votrient (pazopanib) for Soft Tissue Sarcoma: “I am currently battling mesenchymal chondrosarcoma. It originated in my right thigh 2008, had the tumor removed, was cancer free for 3 years then was diagnosed last year with it again, with 5 tumors this time which had spread in my pelvic area, right lung and right armpit (July 2012). I've tried a few chemo therapy treatments and during that time frame, the tumors grew plus one new one appeared. In August 2012 I was placed on Votrient (800 mg), the tumors stopped growing and have been stable ever since. My last scan was June 11, 2013 and all 6 tumors are still holding stable and have shown some shrinkage. The side effects come and go, I am experiencing more muscle pain throughout my body and still some nausea, but that's easily controlled.”
Votrient (pazopanib) for Renal Cell Carcinoma: “I had my right kidney removed December 2014 they thought all cancer was gone but few months later they found cancer in my lymph nodes. I started on Votrient July 2015 at 800 mg but had Doctor reduce amount because of stomachs issues. I'm still nauseated daily and throw up almost every day. My hands are bright red my hair is white I have sores on certain parts of my body that act like blisters then go away after a few weeks. All in all the cancer is shrinking and I have another cat scan this month.”
Votrient (pazopanib) for Renal Cell Carcinoma: “Unfortunately side effects for me have been horrific! I was on 800mg for 6 weeks. I wound up with nausea, extreme hoarseness, high blood pressure, fatigue with sleeping 18 to 22 hours a day. Took a turn for the worse and liver enzymes were high. Could not eat or drink water for 5 days and lost 30 pounds. I was off the Votrient for a month and just started back on half the dose; 400mg. So far so good one evening of slight nausea. Other than a little more tired it appears to be better.”
Votrient (pazopanib) for Renal Cell Carcinoma: “I was diagnosed with Stage IV renal cel carcinoma in January 2012. After two unsuccessful IL-2 treatments, I started taking Votrient in June 2012. At first I had all of the written side-effects but after completely changing my diet, they diminish significantly. Fatigue and whitening of my skin being my only problems. My last CT's continue to show a all of my known tumors as principally stable. The drug works for me! 5 years and counting!”
Votrient (pazopanib) for Renal Cell Carcinoma: “I am taking Votrient for 14 days. My side effect are vomiting, some stomach problems and a temperature around 37℃. Half of my left kidney is removed on June 2015, but a year after I got results that I have MS on my sternum bone and 2 tumors appeared in the soft tissues around the sternum. After a 14 days one of the tumors is getting smaller, I hope this will happen with the other one. Reading the other comments I hope side effect will go away and tumors will be gone. I am 23 years old. God bless everyone.”
Votrient (pazopanib) for Renal Cell Carcinoma: “diagnosed Jan 2, 2015 with renal cell carcinoma. I'm 61 and have been a picture of health my whole life. Right kidney had a tumor and they were going to remove until found 2 leisions on my liver. First med I did not respond to and been on Votrient for 2 weeks. After 1 week they felt I was responding. Side effects are bad with vomiting and diarrhea that it drains me. Hard to eat as food doesn't taste right and now my tongue has a burnt taste so nothing tastes good and have lost a lot of weight in short periods of time. sleep 10 -12 night and 2 hr nap. They say this is all typical for everyone. How long has it taken everyone to finally get back to feeling normal. I use a walker around house and wheelchair for dr”
Votrient (pazopanib) for Soft Tissue Sarcoma: “I have started taking Votrient about three weeks ago. One tablet in the morning, one tablet in the afternoon, and one tablet before bedtime. I would be sick during the day (nausea, extreme fatigue, and no appetite.) I told my doctor about my experience and she suggested to take the tablets all at once before going to bed. I have been doing this for a week, and it is not too bad except waking up in the morning feel exhausted. But in the afternoon I would feel fine. I think the medication is working because I always have tumor pain and I will be going to the doctor this week for signs of some shrinkage.”
Votrient (pazopanib) for Soft Tissue Sarcoma: “After 4 failed chemo regimens, the docs decided to try votrient out. The first week or two were the toughest. The worst side effect was the tumor pain, which was in my chest/back. Also some fatigue, loss of appetite and diarrhea. 3 months later (now), I feel well and there has been some slight shrinkage of my tumors. I'm also back in the gym. White hair kicked in within the first month. I'm a 22 year old covered in white hair lol”
Votrient (pazopanib) for Renal Cell Carcinoma: “I am 70, female. 19 years ago had right kidney removed due to renal cell cancer. In spring of 2016 my shoulder began to bother me, and it got worse until my upper arm broke just below the shoulder, due to renal cell cancer which had metastized to my upper arm bone, my pancreas tail, and two spots on my liver. I first had two weeks of IL-2 which gave me awful side effects and no changes to the cancer tumors. Have been on Votrient since September 2015. November scan shows tumors shrinking. Feb 2017 shows tumors are still shrinking. Side effects are diarrhea every day, body and muscle pain, scaly sores on my bottom, fatigue, and just recently pain in my hands. I take 800 mg daily, late in the day. I take Tramadol for the body pain.”
This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
More about pazopanib
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- Drug class: VEGF/VEGFR inhibitors