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Pazopanib User Reviews & Ratings (Page 4)

Brand names: Votrient

Pazopanib has an average rating of 8.0 out of 10 from a total of 92 reviews on Drugs.com. 74% of reviewers reported a positive experience, while 9% reported a negative experience.

Reviews for Pazopanib

Commonly mentioned side effects
  • SSi...
  • December 11, 2017

For Soft Tissue Sarcoma "Once more, scan done in the last week of Nov 2017. No changes, it is stable. Hope this continues. Life is continuing without any side effects, all daily work is going on. Started with some yoga and breathing exercises."

6 / 10
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  • For...
  • Taken for 1 to 6 months
  • November 24, 2021

Pazopanib for Renal Cell Carcinoma "Daddy has clear cell renal cell carcinoma. He was first put on Opdivo and Yervoy-an immunotherapy. This worked great! It was shrinking my dad's tumors that he had in his stomach, liver, lungs, and right atrium (heart). It even got rid of all the cancer in his stomach. The cancer spread to his brain, and he had to be put on chemotherapy. Votrient had a lot of side effects: nausea, super high blood pressure, major fatigue, and chemo brain fog. He lost 80 pounds on Votrient from not eating. Became frail and fragile, and we were afraid he would die from malnutrition. We begged the doctor to take him off it because she even said he wouldn't live much longer on it, but the issue was the Votrient was SHRINKING the tumors in his liver. This was a sign it was working. His doctor put him on dexamethasone 2 mg, which helped his energy levels and his appetite tremendously. He gained 40 pounds! He was on Votrient 6 months, but BP and brain fog got worse, though, so she then put him on Avastin."

5 / 10
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  • Sal...
  • Taken for 1 to 2 years
  • December 23, 2016

For Renal Cell Carcinoma "My husband was diagnosed with RCC stage 2 in Oct. Last year. He had 1 kidney removed and was on pazopanib 800 mg. But this has been reduced to 400 mg due to severe side effects. Now he takes the 400 mg for 10 days and discontinues for 3 days every time. His oncologist is happy with the test results for now, at least for around 9-10 days per month, he can eat a little more."

8 / 10
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3 Report

Frequently asked questions

  • Bin...
  • Taken for 2 to 5 years
  • November 30, 2016

For Renal Cell Carcinoma "I have stage 4 RCC. The drug worked for 4 years, the docs were surprised that it worked so long. I had most of the side effects: diarrhea, hair turning white, stomach cramps, but better than the pain. The tumors ate through a rib, 2 neck vertebrae, and my kidney, and some small ones in my lungs. The kidney and vertebrae were removed. The tumors doubled in size. I am now on Afinitor."

10 / 10
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  • Bob...
  • Taken for 5 to 10 years
  • July 2, 2024

For Renal Cell Carcinoma "I was diagnosed Christmas Eve 2007 with a stage 4 tumor on the right kidney. Had nephrectomy of the R kidney, adrenal gland, and a portion of the renal vein in Jan 08. A few months later had a tumor on the L adrenal gland removed. In 2014 RCC met on the left shoulder blade; had 1/3rd of the blade removed. In 2015 a scan showed 7 lesions of various sizes on the liver. Started on 800 mg daily of Votrient in March 2015. Overnight my hair went from dark brown to grey. This is the only side effect I have experienced. The tumors on the liver have gone from 7 to 2 in about 9 years. I do have fatigue, but it is due to a lack of adrenal glands and no hormones. I take synthetic meds for fatigue and replace some hormones. After 5 years, I started having severe diarrhea, so I take a combo of Imodium AD and a probiotic. It helps control it. I feel great as of today, but early on with RCC, had problems walking but could still function. Daily exercise is a must even when one does not feel up to it."

10 / 10
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  • Sou...
  • Taken for 1 to 6 months
  • January 26, 2022

For Renal Cell Carcinoma "My father-in-law (age 76) suffered from renal cell carcinoma. After nephrectomy of the affected kidney, he was fine with a single kidney for more than 1 year. His creatinine was around 1.1 to 1.2 (with a single kidney). He did not have any high blood pressure or diabetes. However, after a routine CT, a few questionable nodules were detected in the lungs. Without cross-verification (like repeat scan/biopsy/PET scan, etc.), his oncologist prescribed him pazopanib 800 mg per day. Soon after starting the medicine, his blood pressure became extremely high (200/100), and creatinine started jumping from 1.1, 1.8, 2.2, 2.8, 3.2, and 3.5 in 3 months. His platelet dropped from 165,000 to below 50,000 with a lot of side effects (vomiting, diarrhea, etc.). We repeatedly informed the oncologist, but he was in denial mode. When we consulted a nephrologist, he stopped the medicine. The deteriorating renal function stopped at creatinine 3.5. But, unfortunately, his platelet did not recover from below the 50,000 mark, and he died due to a cerebral hemorrhage."

1 / 10
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  • Bre...
  • December 21, 2010

Pazopanib for Renal Cell Carcinoma "This is my husband's second month on Votrient. He had a CT today, and it shows significant shrinkage in the tumors in his lungs. The only side effect he is experiencing is high blood pressure."

8 / 10
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  • Anonymous
  • May 8, 2011

Pazopanib for Renal Cell Carcinoma "Taking 600 mg of Votrient. Taken at night seems to reduce the side effects significantly."

5 / 10
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117 Report
  • Mrs...
  • Taken for 1 to 2 years
  • January 12, 2016

Pazopanib for Renal Cell Carcinoma "My husband has been on Votrient for a year. He has experienced some gastric issues and foot pain, but overall his tumors are shrinking."

9 / 10
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67 Report
  • rcb...
  • January 30, 2011

Pazopanib for Renal Cell Carcinoma "Very effective. Have lost a lot of weight, but side effects not as extreme as Sutent for me. Started taking 9/20/10 still on it 2/11."

10 / 10
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80 Report
  • Ser...
  • May 12, 2016

Pazopanib for Soft Tissue Sarcoma "Have been on Votrient about six months. Virtually no side effects except for the white hair. Tumors are stable."

10 / 10
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39 Report
  • Kat...
  • October 8, 2020

Pazopanib for Soft Tissue Sarcoma "I have been taking Votrient for 5 years now. The tumors in my bones shrank a bit at first, but it stopped. It has stayed the same level for more than 5 years."

9 / 10
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21 Report
  • Sho...
  • Taken for 1 to 2 years
  • August 6, 2018

Pazopanib for Renal Cell Carcinoma "I've had a very good experience with this drug and have been on it since Nov 2016. Diarrhea has been a side effect, but a small price to pay to feel overall very good!"

10 / 10
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22 Report
  • lll...
  • Taken for 1 to 6 months
  • May 21, 2018

Pazopanib for Renal Cell Carcinoma "With Votrient, I had no major side effects, only loss of appetite and weight loss so far. Slowed progression of cancer down significantly."

10 / 10
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  • Fly...
  • Taken for 1 to 2 years
  • November 15, 2016

Pazopanib for Soft Tissue Sarcoma "Have been on Votrient for almost 12 months. The first 6 months on 400 mg a day, sometimes not taking it at all because the side effects were so horrendous. Then it was upped to 800 mg a day."

6 / 10
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  • man...
  • Taken for less than 1 month
  • August 7, 2017

Pazopanib for Renal Cell Carcinoma "Started treatment 7 days ago, no real side effects, only lethargic all the time."

6 / 10
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8 Report
  • Sum...
  • Taken for 1 to 6 months
  • November 3, 2016

Pazopanib for Renal Cell Carcinoma "My father had passed away after taking pazopanib for just 3 months due to tumor rupture because of this tablet. Please do not consume it."

1 / 10
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13 Report

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