Pazopanib and Blood Pressure: What Users Say

• gen...
• Taken for 2 to 5 years
• March 31, 2015

For Renal Cell Carcinoma "I have been taking 800mg of Votrient daily since March 2012 to treat Renal Cell Carcinoma tumors, which developed when the cancer spread from a large tumor on my right kidney. Votrient has been effective in stopping the growth of the tumors and shrinking a few. Side effects experienced: treatable elevated blood pressure and diarrhea."

• Anonymous
• March 25, 2011

For Renal Cell Carcinoma "Votrient was effective in shrinking tumors in lungs and inhibiting progression of tumors in spine and brain; but I had to discontinue it due to elevated liver enzymes. This happened with an 800 mg dose and a reduced dose of 400 mg. Side effects experienced early in treatment included elevated blood pressure (treated) and fatigue (tolerable)."

• Anonymous
• September 29, 2017

For Renal Cell Carcinoma "I have been on Votrient since April. Had to stop after 2 weeks because blood pressure put me in the hospital, being too high. Started taking it again at 1 a day. I am now up to 4 (800 mg) a day. Doing better the longer I take it. Have more good days where I feel like doing my housework. Food doesn't taste good. I can eat fruit: pineapple, grapes, cantaloupe, things like that. Even some Chinese food some days, like sweet and sour chicken. Chicken tastes best. No beef or pork tastes good. Took my second CT scan this week, waiting on results. The first one said it hadn't grown any, so that's a plus. I too have many side effects: diarrhea, the worst. Fatigue, taste issues, white hair everywhere, my hands are beginning to get very rough also. I have bruises come up too."

• l59...
• January 28, 2018

For Renal Cell Carcinoma "My mum is soon to be 90 and had never been in the hospital, only to have her four children. Mum got pneumonia, and in November 2017, was in the hospital for 6 days. Diagnosed with pneumonia and an enlarged heart. Mid-December 2017, she came back to the hospital with labored breathing. Tests done showed a collapsed lung due to fluid and, to our shock, later diagnosed with RCC, gone into the renal artery and metastasized to the liver. By Wednesday, January 24, 2018, she started on Votrient, 2 a day. She already has white hair, so I don't think that will change, but she was taken off blood pressure tablets in the hospital (which she had been on for 50 years) as her blood pressure was perfect. On Votrient, it has gone up again, so I am taking her tomorrow to see if they want to put her back on them. Mum has 20 great-grandchildren and 12 grandchildren and wants desperately to be able to go to my son's wedding in March, and her birthday is May 1st. The oncologist is confident that she will make both... Here's hoping."

• Sun...
• Taken for 1 to 2 years
• May 1, 2021

For Renal Cell Carcinoma "Update... on Votrient 800 mg since January 2020, with a short period of treatment paused because of the pandemic. I resumed in July 2020. The only side effect is elevated blood pressure (controlled). The latest scan showed dramatic shrinkage of RCC mets in the remaining kidney, pancreas, and adrenal gland. Also, lung mets are no longer visible on the latest scan. I feel very fortunate that this drug is working for me. My thoughts are with you all. Keep fighting."

• 3...
• October 17, 2021

For Renal Cell Carcinoma "I was diagnosed with renal cancer 6 years ago. My left kidney was removed. I received no chemotherapy or radiation due to the fact it was ineffective on a clear cell carcinoma. I had 3 nodules on my lungs at the time it was diagnosed. 5 years later, a CT scan showed the 3 nodules grew and two more appeared on my right lung. A wedge section was removed from my left lower lung. The metastasis was confirmed to stage 4 cancers. After 2 opinions, I tried a combination of Keytruda infusion and Inlyta tablets. I had a severe reaction to the Keytruda, thankfully, the doctor and nurses saved me. I had several options and went for Votrient. I have had no serious side effects. My blood pressure became elevated but was brought under control with an increase of blood pressure medication. I just had a CT scan. The 3 remaining nodules shrunk and 1 disappeared. No other signs of cancer. I am a new user, but so far, I think this drug is a miracle."

• Kiw...
• Taken for 5 to 10 years
• March 9, 2021

For Renal Cell Carcinoma "Using Votrient from Jan 2013 until July 2020. Had right kidney removed in Nov 2011 on diagnosis of my cancer. Metastasized in my submandibular and parotid glands in Sept 2012, starting Votrient in Jan 2013. Side effects appear to improve over the years, the main issue was blood pressure and diarrhea. I stopped Votrient to try SRT, which appears to be working."