Pazopanib for Soft Tissue Sarcoma User Reviews

• R35...
• February 19, 2015

Pazopanib "I was diagnosed with 4 fibrosarcoma tumors in my liver on July 15, 2014. I did 6 weeks of GEMS/Taxol, and after the scan showed two more tumors in the liver and four now in my lungs. My doctor put me on Votrient and scanned me once again after six weeks. All the tumors in my lungs have shrunk to half their size, and one tumor in the liver has also shrunk to half its size, while all the others in the liver are dying from the inside out."

• Col...
• Taken for 1 to 2 years
• April 27, 2014

Pazopanib "Felt it is time for an update. It's April 26, 2014, and I've been on Votrient since August 2012. So far, tumors remain stable and continue to show shrinkage. I'm still taking the same dosage, 800mg per day."

• Fai...
• September 26, 2014

Pazopanib "I was diagnosed with stage 4 Leiomyosarcoma on July 16, 2013. Tumors in my stomach, liver, and a few affected lymph nodes. Had surgery and removed 40% of my stomach on August 30, 2013. Surgery was a success. I Underwent 4 1/2 months of chemo with minimal shrinkage to existing tumors but did stunt the growth of the tumors. At that point, my tumors were considered inoperable. Started Votrient on February 14, just found out my tumors have shrunk enough on my liver to be operable. Liver Surgery scheduled on October 14. So happy, praying Votrient is our miracle. Good luck to others with my condition."

• Mrs...
• Taken for 6 months to 1 year
• June 24, 2013

Pazopanib "I am currently battling mesenchymal chondrosarcoma. It originated in my right thigh in 2008, had the tumor removed, was cancer-free for 3 years, then was diagnosed last year with it again, with 5 tumors this time which had spread in my pelvic area, right lung, and right armpit (July 2012). I've tried a few chemotherapy treatments and during that time frame, the tumors grew plus one new one appeared. In August 2012, I was placed on Votrient (800 mg), the tumors stopped growing and have been stable ever since. My last scan was June 11, 2013, and all 6 tumors are still holding stable and have shown some shrinkage. The side effects come and go, I am experiencing more muscle pain throughout my body and still some nausea, but that's easily controlled."

• X_C...
• Taken for 1 to 6 months
• May 4, 2016

Pazopanib "After four failed chemo regimens, the doctors decided to try Votrient. The first week or two was the toughest. The worst side effect was the tumor pain, which was in my chest and back. Additionally, there was some fatigue, loss of appetite, and diarrhea. Three months later (now), I feel well, and there has been some slight shrinkage of my tumors. I'm also back in the gym. White hair kicked in within the first month. I'm a 22-year-old covered in white hair, lol."

• Bel...
• Taken for less than 1 month
• March 17, 2013

Pazopanib "I have started taking Votrient about three weeks ago. One tablet in the morning, one tablet in the afternoon, and one tablet before bedtime. I would be sick during the day (nausea, extreme fatigue, and no appetite.) I told my doctor about my experience and she suggested to take the tablets all at once before going to bed. I have been doing this for a week, and it is not too bad except waking up in the morning feel exhausted. But in the afternoon I would feel fine. I think the medication is working because I always have tumor pain and I will be going to the doctor this week for signs of some shrinkage."

• Key...
• February 22, 2013

Pazopanib "Started taking Votrient 800 mg last year. After 23 days, had to stop due to high blood pressure and got a fistula. 3 months later, started back on at 400 mg. Seems to be doing better and taking 2 blood pressure medications to control it. Normal side effects like the ones I read about on this site. Last CT showed no major growths of my Sarcomas."

• Con...
• January 24, 2013

Pazopanib "I started taking it about 6 weeks ago for sarcoma. The only trouble I have had with it has been some gastro discomfort. But I was taking it first thing in the morning on a totally empty stomach. Now I eat breakfast and take it two hours later. Then I eat some yogurt an hour later, and so far all the stomach pain is gone. I do have some food allergies and a slight case of irritable bowel syndrome, so I was not really surprised when I had the stomach pain. I have a CT on 2/13/13 to see if the tumors are continuing to stay shrunk. But I feel fine."

• jan...
• March 1, 2016

Pazopanib "I'm a 39-year-old guy from Sweden. I have soft tissue sarcoma in my stomach wall, and it spread to the bones (legs, both femoral head and sternum, and my skull that was removed). I have started Votrient 2015.08, 800 mg/day. The first 2 weeks, I had a fever and felt really sick, stomach problems, pain, and diarrhea. It took about 1-2 months before I felt normal with this medication. The pain from my bone mets disappeared pretty fast (1 month). I have had new scans after 3 months, and the results were pretty good, sternum and right leg had nothing left :) In the left leg, there is only about 30% left. I'm going to have new scans this month, so let's see, hoping for more good news.... The stomach tumor was the same."

• elw...
• November 17, 2014

Pazopanib "Wife is on this now for her 4th week (800 mg), she has soft tissue in the right lung after mets from the uterus. Leiomyosarcoma (sp). A month ago, she was coughing every 2 minutes, now, not so much, but she is tired, has nausea, and headaches. No appetite, and when she ate solid food, it would always come back up. Now her food consists of 4-6 smoothies a day. Got a Vitamix after many recommended it on other websites on the internet. You fellow patients who have gone before her and have reported your experiences are the 'only' thing that have kept her pressing forward. She has a large tumor in her chest, and it is hoped that this will hollow it out or something. Her first chemo, GEMS/Taxol, only worked for 3 months. Then it started regrowing."

• Mea...
• Taken for 6 months to 1 year
• February 15, 2020

Pazopanib "I was on Votrient for 6 months at 600 mg a day. The diarrhea, fatigue, and cramping were so bad that I got off the treatment. While on it, my tumors and nodules were shrinking. I immediately felt better when I got off the treatment, so I golfed, rode my bike, and had a wonderful summer. After a summer being off Votrient, my doctor talked me into trying again at a lower dose. I started over at 200 mg for a month and felt good, so I increased to 400 mg a day. I started to feel fatigue and decided to stay at this dose. It's been 4 months now since I started over, and all tumors and nodules have shrunk considerably, and uptake on the PET scan is way lower. It seems to be working. Thinking now about going back to work if I could just get past the need for afternoon naps. I feel blessed. It could be so much worse. Glad I tried Votrient again at a lower dose."

• vot...
• February 22, 2017

Pazopanib "My wife has a very aggressive cancer that started in the uterus (removed a 2.5 lb tumor last June), which had metastasized to the lung and elsewhere. She was stage 4 at diagnosis. Two chemo drugs did not work. After a bad spell at Christmas (including kidney failure), they were talking about hospice but also wanted to try Votrient. The Votrient resulted in visible tumor shrinkage within 24 hours. We have continued with the Votrient, and after six weeks, the lung tumors shrank by 20 and 30 percent. The doctor tells us we may get one more good scan, and then it may stop working. But the reprieve has been sweet, and things are going in the right direction. She takes 3 pills (600 mg), not 4. About the fatigue: she gets some low-dose Ritalin."

• SSi...
• Taken for 1 to 2 years
• July 13, 2018

Pazopanib "This June I have completed 1 year with this tablet. I had started an 800 mg dose per day on 1st June 2017. The side effects I went through initially were diarrhea and mouth sores. I am still on these tablets. The sizes of the tumors are under control, and SUV uptakes have gone down. Fit and fine, no side effects now. It looks like the body has gotten adjusted to these tablets."

• Kat...
• Taken for 5 to 10 years
• December 15, 2020

Pazopanib "I'm taking Votrient for over 5 years, it stopped the spread of mets. Just before I started the trial, every scan like MR, CT, PET was showing new mets. I had clinical chemo like doxorubicin, ifosfamide, and it stopped only for a while. My oncologist was always suggesting Votrient, but it’s the 4th line treatment and expensive for the government (complicated to explain when health care is for “free” in my country). Anyway, for me, it was the last option. The regional CEO oncologist refused me the treatment. But my oncologist is a researcher and sent me to a capital hospital. So that since 18.9.2015, I’m on Votrient. First of all, I had no side effects, then, after half a year, I started having nausea, diarrhea, fatigue. And of course, my skin is as pale and cannot find the lightest foundation tone, and color my hair and henna brows and lashes..."

• CCR...
• Taken for less than 1 month
• September 15, 2023

Pazopanib "I started Votrient 10 days ago on 400mg. I feel no side effects. I was diagnosed one year ago with a rare soft tissue sarcoma called 'epithelioid hemangioendothelioma', stage IVB. We did 2 surgeries, which were very successful, but I still have some nodules on both lungs and liver. All nodules left have been stable for the last year, but one nodule on the upper right lung showed some growth, so that's why we decided to start the medication. We did a test using a live cell biopsy that showed good results for Votrient. I hope to see some good results on the CT scan in 3 months. I maintain a very healthy lifestyle, I only eat healthy meals, no processed food, no sugar, no gluten, or dairy. I also exercise, do yoga, attend dancing classes, and try to live my life as normally as possible."

• Jef...
• Taken for 1 to 6 months
• August 21, 2020

Pazopanib "Stage 4 soft tissue sarcoma. I was on 800 mg of Votrient. After 3 weeks, the doctor took it down to 600 mg because the side effects were too much for me. On 600 mg, they were still bad, but he said he couldn't go lower. After 3 months, the cancer had grown and spread to my spine. Now I am having radiation on the spine, then chemo. I was told if I do nothing, I have 'weeks to months' left. If I do chemo, 'months to a year,' some choice, huh? I'll try the chemo, but if the side effects are not worth it, I'll stop."

• SSi...
• August 28, 2017

Pazopanib "I am on Votrient from June 1st, and yesterday had my first scan (3 months on Votrient, 800 mg dose). It has shown a marginal increase in the size of the tumor, but the SUV uptake has gone down from 4.6 to 2.7. As per my doctor, the tablets are working, and we will continue the same. Is it really working?"

• Tin...
• July 18, 2015

Pazopanib "I just started Votrient 3 days ago. I have no side effects at all. I've felt great the past several days, just like my old self before I was diagnosed with an 11.2 cm tumor in my pelvis that was surgically removed in Feb of 2015. However, the leiomyosarcoma metastasized to my liver, lung, and I was told bones. After 6 treatments of Gemzar and Taxotere, the liver and lung metastases spread and grew. I was sent to another hospital for a Phase II trial drug to build the immune system, charging the T-cells to go after the cancer, while Dixol chemo attacks the cancer. The Dixol could only be used 10 due to possible problems with the heart pump. I said no thanks, that's when I asked what else they had, so I was put on Votrient."

• dku...
• December 19, 2015

Pazopanib "My mother went on this wonderful drug, and it was bad. It burnt and blistered the inside of her mouth and throat to the point she could not eat solids anymore. She lost all her strength to the point we had to carry her to the bathroom, and finally, she lost her life."

• Ren...
• February 22, 2021

"In May 2016, I was diagnosed with metastatic mesenchymal chondrosarcoma. The mass was in my left fibula, and I took two different chemotherapy treatments (doxorubicin + ifosfamide) followed by surgical resection in October 2016. Devastated! Cancer metastasized in my lungs and abdominal area. I got a bone scan done, blood work done, then started chemotherapy using doxorubicin. I maxed out on doxorubicin, took a break, and started Caelyx chemotherapy. Got a scan. Found out this was not working. The mass in my left retroperitoneal area was now 9 x 7 cm. The doctor gave me five high doses of radiation on October 1, 2020. I started the pazopanib on October 27, 2020, at 600 mg/day, had a scan on February 17, 2021, and saw the doctor on February 22, 2021. OMG! Thank you, pazopanib, for keeping this metastatic disease stable. Tumors have shrunk and others are stable. I will remain on 600 mg of pazopanib and will see the doctor in three months for another scan and update."

• SSi...
• December 11, 2017

"Once more, scan done in the last week of Nov 2017. No changes, it is stable. Hope this continues. Life is continuing without any side effects, all daily work is going on. Started with some yoga and breathing exercises."

• Ser...
• May 12, 2016

Pazopanib "Have been on Votrient about six months. Virtually no side effects except for the white hair. Tumors are stable."

• Kat...
• October 8, 2020

Pazopanib "I have been taking Votrient for 5 years now. The tumors in my bones shrank a bit at first, but it stopped. It has stayed the same level for more than 5 years."

• Fly...
• Taken for 1 to 2 years
• November 15, 2016

Pazopanib "Have been on Votrient for almost 12 months. The first 6 months on 400 mg a day, sometimes not taking it at all because the side effects were so horrendous. Then it was upped to 800 mg a day."