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Medications for Mantle Cell Lymphoma

Mantle cell lymphoma is a rare form of non-Hodgkin's lymphoma that develops from mature B lymphocytes that are from a region of the lymph nodes called the 'mantle zone'. Symptoms can include swollen lymph glands, fever, night sweats, fatigue and unexplained weight loss. There may also be abdominal swelling due to enlargement of the liver or spleen.

Drugs used to treat Mantle Cell Lymphoma

The following list of medications are in some way related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Calquence 9.0 2 reviews for Calquence to treat Mantle Cell Lymphoma
Rx N
Generic name:
acalabrutinib systemic
Drug class:
BTK inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Revlimid Rate Add review
Rx X N
Generic name:
lenalidomide systemic
Drug class:
miscellaneous antineoplastics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
rituximab Off-label Rate Add review
Rx C N
Generic name:
rituximab systemic
Drug class:
antirheumatics, CD20 monoclonal antibodies
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Off-label:
Yes
acalabrutinib 6.7 3 reviews for acalabrutinib to treat Mantle Cell Lymphoma
Rx N
Generic name:
acalabrutinib systemic
Brand name:
Calquence
Drug class:
BTK inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Velcade Rate Add review
Rx D N
Generic name:
bortezomib systemic
Drug class:
proteasome inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Brukinsa 8.0 2 reviews for Brukinsa to treat Mantle Cell Lymphoma
Rx N
Generic name:
zanubrutinib systemic
Drug class:
BTK inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
bortezomib Rate Add review
Rx D N
Generic name:
bortezomib systemic
Brand name:
Velcade
Drug class:
proteasome inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
lenalidomide Rate Add review
Rx X N
Generic name:
lenalidomide systemic
Brand name:
Revlimid
Drug class:
miscellaneous antineoplastics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
zanubrutinib 8.0 3 reviews for zanubrutinib to treat Mantle Cell Lymphoma
Rx N
Generic name:
zanubrutinib systemic
Brand name:
Brukinsa
Drug class:
BTK inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Jaypirca Rate Add review
Rx N
Generic name:
pirtobrutinib systemic
Drug class:
BTK inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
pirtobrutinib Rate Add review
Rx N
Generic name:
pirtobrutinib systemic
Brand name:
Jaypirca
Drug class:
BTK inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
cyclophosphamide Rate Add review
Rx D N
Generic name:
cyclophosphamide systemic
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
cytarabine Off-label Rate Add review
Rx D N
Generic name:
cytarabine systemic
Drug class:
antimetabolites
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
methotrexate Off-label Rate Add review
Rx X N X
Generic name:
methotrexate systemic
Drug class:
antimetabolites, antirheumatics, antipsoriatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Tecartus Rate Add review
Rx N
Generic name:
brexucabtagene autoleucel systemic
Drug class:
miscellaneous antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
brexucabtagene autoleucel Rate Add review
Rx N
Generic name:
brexucabtagene autoleucel systemic
Brand name:
Tecartus
Drug class:
miscellaneous antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
doxorubicin Off-label Rate Add review
Rx D N
Generic name:
doxorubicin systemic
Drug class:
antibiotics/antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
mitoxantrone Off-label Rate Add review
Rx D N
Generic name:
mitoxantrone systemic
Drug class:
antibiotics/antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
vincristine Off-label Rate Add review
Rx D N
Generic name:
vincristine systemic
Drug class:
mitotic inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes

Frequently asked questions

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.