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Medications for Breast Cancer, Metastatic

Other names: Metastatic Breast Cancer

About Breast Cancer, Metastatic:  Metastatic breast cancer (Stage IV breast cancer) is an advanced form of breast cancer that occurs when breast cancer cells spread from the breast into surrounding tissue and distant organs.

Drugs Used to Treat Breast Cancer, Metastatic

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
letrozole D N 19 reviews
6.0

Generic name: letrozole systemic

Brand name:  Femara

Drug class: hormones/antineoplastics, aromatase inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Femara D N 8 reviews
7.0

Generic name: letrozole systemic

Drug class: hormones/antineoplastics, aromatase inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Xeloda D N 10 reviews
5.0

Generic name: capecitabine systemic

Drug class: antimetabolites

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Arimidex D N 3 reviews
7.0

Generic name: anastrozole systemic

Drug class: hormones/antineoplastics, aromatase inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Herceptin D N 2 reviews
10

Generic name: trastuzumab systemic

Drug class: HER2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Ibrance N 33 reviews
6.0

Generic name: palbociclib systemic

Drug class: CDK 4/6 inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

anastrozole D N 6 reviews
7.0

Generic name: anastrozole systemic

Brand name:  Arimidex

Drug class: hormones/antineoplastics, aromatase inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Faslodex D N 7 reviews
5.0

Generic name: fulvestrant systemic

Drug class: hormones/antineoplastics, estrogen receptor antagonists

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

tamoxifen D N Add review Rate

Generic name: tamoxifen systemic

Brand name:  Soltamox

Drug class: hormones/antineoplastics, selective estrogen receptor modulators

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Taxol D N 3 reviews
8.0

Generic name: paclitaxel systemic

Drug class: mitotic inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Tykerb D N 1 review
10

Generic name: lapatinib systemic

Drug class: EGFR inhibitors, HER2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

capecitabine D N 12 reviews
6.0

Generic name: capecitabine systemic

Brand name:  Xeloda

Drug class: antimetabolites

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Abraxane D N 1 review Rate

Generic name: paclitaxel protein-bound systemic

Drug class: mitotic inhibitors

For consumers: dosage, interactions, side effects

Taxotere D N 1 review
9.0

Generic name: docetaxel systemic

Drug class: mitotic inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Halaven D N 7 reviews
9.0

Generic name: eribulin systemic

Drug class: mitotic inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Gemzar D N 1 review
7.0

Generic name: gemcitabine systemic

Drug class: antimetabolites

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

fulvestrant D N 8 reviews
5.0

Generic name: fulvestrant systemic

Brand name:  Faslodex

Drug class: hormones/antineoplastics, estrogen receptor antagonists

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

palbociclib N 35 reviews
6.0

Generic name: palbociclib systemic

Brand name:  Ibrance

Drug class: CDK 4/6 inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Perjeta D N Add review Rate

Generic name: pertuzumab systemic

Drug class: HER2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

docetaxel D N 1 review
9.0

Generic name: docetaxel systemic

Brand name:  Taxotere

Drug class: mitotic inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Ixempra D N Add review Rate

Generic name: ixabepilone systemic

Drug class: mitotic inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

trastuzumab D N 2 reviews
10

Generic name: trastuzumab systemic

Brand names:  Herceptin, Ogivri

Drug class: HER2 inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

paclitaxel D N 3 reviews
8.0

Generic name: paclitaxel systemic

Brand name:  Taxol

Drug class: mitotic inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

pertuzumab D N Add review Rate

Generic name: pertuzumab systemic

Brand name:  Perjeta

Drug class: HER2 inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Soltamox D N Add review Rate

Generic name: tamoxifen systemic

Drug class: hormones/antineoplastics, selective estrogen receptor modulators

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

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Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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