Duobrii Side Effects

Generic name: halobetasol / tazarotene topical

Medically reviewed by Drugs.com. Last updated on Oct 26, 2024.

Note: This document provides detailed information about Duobrii.

Applies to halobetasol/tazarotene topical: topical application lotion Side Effects associated with halobetasol / tazarotene topical. Some dosage forms listed on this page may not apply specifically to the brand name Duobrii.

Applies to halobetasol/tazarotene topical: topical application lotion.

Precautions

It is important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.

If your symptoms do not improve within a few days or weeks, or if they become worse, check with your doctor.

Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away.

To make sure you are not pregnant when you start using this medicine, you may need to start using it during a normal menstrual period. Also, you must have a negative pregnancy test within 2 weeks before you start using this medicine.

Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and patients who use large amounts for a long time. Talk to your doctor right away if you have more than one of these symptoms while you are using this medicine: blurred vision, dizziness or fainting, a fast, irregular, or pounding heartbeat, increased thirst or urination, irritability, or unusual tiredness or weakness.

Avoid exposing your skin to wind, cold weather, and sunlight, even on cloudy days. Your skin will be more prone to sunburn, dryness, or irritation. Do not use a sunlamp or tanning bed. Use a sunscreen or sunblock lotion with a sun protection factor (SPF) of at least 15 on a regular basis. Wear protective clothing and hats and stay out of direct sunlight, especially between the hours of 10 a.m. and 3 p.m.

It is likely that your skin may become irritated with normal use of this medicine. You should not stop using tazarotene unless your skin becomes too red, dry, puffy, or otherwise irritated. If severe irritation occurs, contact your doctor.

Check with your doctor right away if blurred vision, difficulty with reading, or any other change in vision occurs during or after treatment. Your doctor may want your eyes be checked by an ophthalmologist (eye doctor).

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of Duobrii

Along with its needed effects, halobetasol/tazarotene topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking halobetasol / tazarotene topical:

Other side effects of Duobrii

Some side effects of halobetasol / tazarotene topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to halobetasol / tazarotene topical: topical lotion.

Local adverse events

• Common (1% to 10%): Application site pain, folliculitis, skin atrophy, excoriation, rash, skin abrasion, skin exfoliation^[Ref]

Ocular

• Postmarketing reports: Cataracts, glaucoma^[Ref]

Dermatologic

• Common (1% to 10%): Contact dermatitis
• Frequency not reported: Photosensitivity, sunburn^[Ref]

Endocrine

• Very common (10% or more): Hypothalamic-pituitary-adrenal (HPA) axis suppression (15%)^[Ref]

See also:

Frequently asked questions

• Can halobetasol propionate be bought over-the-counter (OTC)?
• How long should you use Duobrii?
• What happens if you use too much Duobrii?

Further information

Duobrii side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer