Vtama Side Effects
Generic name: tapinarof topical
Medically reviewed by Drugs.com. Last updated on Apr 8, 2025.
Note: This document provides detailed information about Vtama.
Applies to tapinarof topical: topical application cream Side Effects associated with tapinarof topical. Some dosage forms listed on this page may not apply specifically to the brand name Vtama.
Applies to tapinarof topical: topical application cream.
Precautions
It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for any unwanted effects.
If your condition does not improve or if it becomes worse, check with your doctor.
Serious side effects of Vtama
Along with its needed effects, tapinarof topical (the active ingredient contained in Vtama) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking tapinarof topical:
More common side effects
- body aches and pain
- blistering, burning, crusting, dryness, or flaking of the skin
- burning, itching, and pain in hairy areas
- chills
- cough
- difficulty in breathing
- ear congestion
- fever
- headache
- itching, scaling, severe redness, soreness, or swelling of the skin
- loss of voice
- muscle aches and pains
- pus at the root of hair
- shivering
- sneezing
- sore throat
- stuffy or runny nose
- sweating
- unusual tiredness or weakness
Less common side effects
- general feeling of discomfort or illness
- itching or pain of the genital area
- joint pain
- shivering
- sweating
- trouble sleeping
- vomiting
For healthcare professionals
Applies to tapinarof topical: topical cream.
General adverse events
The most frequently reported adverse events included folliculitis and nasopharyngitis.[Ref]
Respiratory
Dermatologic
- Very common (10% or more): Folliculitis (20%)
- Common (1% to 10%): Contact dermatitis, pruritus, urticaria
- Uncommon (0.1% to 1%): Drug eruption[Ref]
Adverse events which resulted in treatment discontinuation in greater than 1% of subjects were contact dermatitis (2.9%) and folliculitis (2.8%).[Ref]
Nervous system
- Common (1% to 10%): Headache[Ref]
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References
1. (2022) "Product Information. Vtama (tapinarof topical)." Dermavant Sciences, Inc.
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Further information
Vtama side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.