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User Reviews for Otezla

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Otezla Rating Summary

User Ratings
10
   
18%(13)
9
   
8%(6)
8
   
7%(5)
7
   
7%(5)
6
   
4%(3)
5
   
11%(8)
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11%(8)
3
   
8%(6)
2
   
10%(7)
1
   
20%(15)
5.2/10 Average Rating
76 Ratings with 80 User Reviews

What next? Compare all 57 medications used in the treatment of Psoriatic Arthritis.

Reviews for Otezla to treat Psoriatic Arthritis

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"I am considering Otezla for my Psoriatic Arthritis, but after reading these reviews I wanted to share something that some of you may find helpful. There is a book entitled "The Great Arthritis Breakthrough" in which the author cites several studies that have attributed many cases of arthritis to bacteria and tests confirmed that a daily low dose of Minocycline antibiotic fended off the arthritis. I tried this regimen and found that it did work great for arthritis, however it did nothing for the Psoriasis. But seriously, if you are in pain like I was, this is worth it. I took Minocycline for about 2 years and then stopped and have have been off of it for two years now. I am only now starting to have a little inflammation in my right middle finger. Anyway, I wanted to share this in case others might find it useful."

davegerard (taken for less than 1 month) April 16, 2018

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"Though I had no side effects when taking other biologics - or any meds - I had terrible respiratory stuff while on this so went off after a week or so. The way they tested it didn't allow me to know what to expect as they seemed they have data only at a 4 month or so mark. I wouldn't recommend it."

   
1.0

syb March 29, 2018

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"I took this drug for 11 months and finally had to come off it. From Feb to May I did notice an improvement with pain but in June my hands and feet had such nerve pain I could hardly walk and had trouble planting my little garden. I was told the nerve pain could not be from Otezla. From day one I had 2 hours with diarrhea and was told that too would pass. It didn't. I stopped the drug in December before Christmas and the nerve pain and diarrhea completely stopped. Mind you I still have sore feet and hands but feel so comfortable. I had been on Methtrexate and Humira before this drug and they too had massive problems. I have always had Irritable bowel syndrome (IBS) but now my Surgeon said it was undiagnosed diverticulitis that I had kept controlled by diet. These drugs made my bowel much worse and now I need a section removed. How sad is that. Is there even a good drug out there?"

   
3.0

Bridget (taken for 6 months to 1 year) March 25, 2018

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"I have had psoriasis and pasoriatic arthritis for the 10 years. I have tried all kinds of creams nothing has helped. Until this pill! OMG I'm completely amazed of how much my psoriatic arthritis has gone with this pill. I would cry every day with pain of the joints . The pain I would have in my neck was soooo bad. This is a amazing pill and everyone should try it. Form my psoriasis it has helped some but for my psoratic arthoritis it has been amazing plus do the 0 copay bc my insurance wanted $3500 a month and I couldn't do that at all. Thanks so much for this pill!!It literally has saved my life with pain daily!!"

   
7.0

nea (taken for 1 to 6 months) March 16, 2018

2 users found this comment helpful.
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"I have been on Otezla going on my 4th year I had plaque psoriasis and swelling of joints I was nauseous for maybe 2 weeks when I started, my ring finger was a size nine and now it’s a size five that’s how much swelling has gone down for me. All my plaque was completely gone by the 3rd month which included my whole head my ears and unmentionable parts! I don’t have depression or any other side affects for me this drug is amazing!"

   
10

Trista7777 (taken for 2 to 5 years) February 26, 2018

4 users found this comment helpful.
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"When ointments are not as effective as they used to be, I started researching other treatments for Psoriasis. It's a constant battle on my head and wearing black is becoming more difficult. I'm not considering injection therapy so Otezla seemed the perfect solution. Side effects began on day 2 and started to subside after 2 weeks. However, the tension headaches got worse and I stopped treatment after 2 1/2 weeks. I saw little impact on my psoriasis, but I probably didn't take it long enough. However, my Psoriatic Arthritis was completely gone, which of course is acting up again. I so wished this would have worked for me."

   
5.0

Hausfrau (taken for less than 1 month) February 24, 2018

1 users found this comment helpful.
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"Was prescribed and took for 8 months for plaque psoriasis and psoriatic arthritis. After a month began to notice a big reduction in plaques but only mild relief in pain. After 4 months began to experience depressed feelings and random dark thoughts while nothing had changed in life circumstances. Decided to go off when scared myself with thoughts of crashing my vehicle while driving. However, be warned the psoriasis plaques is worse now than before I took the meds and the joint pain is back. Would not recommend."

   
3.0

StillSuffering478 February 18, 2018

3 users found this comment helpful.
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"I have now been taking Otezla for 2 years. I have never had bad psoriasis, but psoriatic arthritis has affected me for about 5 years. It took me almost 9 months for my psoriatic arthritis saw any improvement. After 1 year of taking, I thought it was a wonder drug. I have had constant stomach and headache issues that I was willing to accept. I figured it wasn't as bad as having PsA. About 6 months ago it stopped working for me. I started experiencing pretty bad moods and felt like I was falling into depression. I have since moved on to a single dose at bed time. I recently started using CBD oil and it seems to be working pretty well. Worked for a while, but side effects were almost as bad as the condition."

   
4.0

Middleman12345 (taken for 2 to 5 years) January 17, 2018

5 users found this comment helpful.
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"I was prescribed Otezla for psoriatic arthritis. I took it for about 18 weeks. My arthritis improved only minimally. - I experienced the side effects of nausea, diarrhea and headaches throughout the 18 weeks. I stopped the treatment since it wasn't really working for me. And that is where the real trouble began - I had only suffered mild psoriasis over the years. I have not had a significant outbreak in over 25 years. In very short order, after I stopped this medicine, my psoriasis returned with a vengeance!! It's now almost 6 months since I've stopped taking this drug and I'm STILL trying to get the psoriasis under control. I would NOT recommend anyone take this drug."

   
2.0

HodaMac December 18, 2017

6 users found this comment helpful.
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"I have been taking Otezla for psoriatic arthritis as well as psoriasis. At first I thought it was a miracle drug helping with the pain and the patches. I did have terrible (and I mean terrible) problems with my stomach. While it improved slightly, after a year and a half it still kills my stomach. I am going to get off of it because it stopped helping with the pain and my skin is worsening. I stuck with it despite the nonstop bowel movements (and headaches) because I thought it was helping, but now that I'm reverting back it isn't worth the nearly debilitating side effects."

Anonymous (taken for 1 to 2 years) November 30, 2017

1 users found this comment helpful.
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"I was diagnosed with HLA-B27 (a specific protein on your white blood cells that can be a sign of autoimmune disease) Dr told me I had Psoriatic Arthritis gave me a starter pack of Otezla took for 12 days , which all of stiffness and joint pain left, I am also on Phentermine and Topimirate for weight loss, so I didn’t experience any headache, however I did get somewhat depressed and no energy to do anything, I ran out of the starter pack had to get another but was off of it for 3 days, while off of it I noticed my mood was better and back to normal, but this morning oh my all my stiffness and pain are back so I am goin back on the new starter pack and try to deal with mood thing because this pain is crazy, I also do have a sinus head cold that I have had for 4 days but I kinda chalked that off to the time of year and weather!"

   
7.0

Kandi313 (taken for less than 1 month) November 13, 2017

3 users found this comment helpful.
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"Been on Otezzla for about 6 months. The first few months I thought my prayers had been answered. My skin cleared up by 75 percent in 3 months. I have psoriasis and psoriatic arthritis. My pain had decreased as well. I did have stomach issues, severe headaches and major pressure in my ears and can hardly hear! The medication has quit working. Not clearing up my scales or itching at all! And the pain! The pain in my fingers, elbows and feet is worse than ever. I'm up all during the night from joint pain, now have nerve pain in my feet and cannot open a bottle of water in the mornings. Very sad this didn't work out because I refuse to take immune suppression medication."

   
5.0

Denny789824 September 17, 2017

5 users found this comment helpful.
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"On otezla for a short time 4 weeks must come off it because of surgery right shoulder rotator cuff. Up to this point minor side effects but did cause some sleep issues which could also be contributed my upcoming surgery. Had such good results with Biologicals for 15 yrs. until they lost there effectiveness. Now as I get older 67 would like to try something less immunosuppressive. Not encouraged by comments I read. But everyone is different so I will stick it out for four months"

   
4.0

Mattcat (taken for 1 to 6 months) September 12, 2017

4 users found this comment helpful.
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"I took Otezla twice, two years apart. My first experience helped my psoriasis and psoriatic arthritis within 3 months with minimal side effects. I had loose stool for a couple of days and a mild headache. THEN I developed a very aggressive breast cancer and was advised to stop Otezla.. I underwent chemotherapy, bilateral mastectomies and reconstruction. One year later, I began taking Otezla again because my psoriasis and PA came back with a vengeance, as predicted. Four months into treatment, I developed breast cancer in my sternum. Once again, I quit the Otezla and have since undergone radiation treatment. I did not tick the boxes for a patient at high risk for breast cancer. I feel my cancer may well have been a direct result of Otezla"

   
1.0

Joschally September 1, 2017

10 users found this comment helpful.
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"I took otezla for about 5 months for psoriatic arthritis. I experienced headaches and upper respiratory infections almost the entire time. I saw little, if any, improvement to my arthritis pain and inflammation."

   
1.0

Yandy (taken for 1 to 6 months) August 1, 2017

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"Since the first pill on Otezla I started to get severe sinus headaches that could not be remedied by Tylenol or Advil. Nasal congestion began shortly after that as did steady head pain. I am now 7 days on the pills and I stopping due to these headaches, loose bowel movements, sinus congestion and pain, headaches and most importantly INSOMNIA!! I have been up 2 days straight and have stopped these pills last night. Since being on these pills I have not slept more than 2 hrs per night if at all. My foot pain has been lessened as well as the pain in my fingers but the side effects are just not worth it. Still getting sharp pains in my toes and difficulty with hip joint and knees while I did not have before starting Otezla. Not the drug for me!"

cdep July 23, 2017

17 users found this comment helpful.
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"I am technically taking this for reactive arthritis, that I have struggled with on and off for 15 years. Most recently on a 4 year stint, where I have been talking steroids. The idea was that this would allow me to get off of steroids. It took a few months to seem to help, but now (6 months) I have been weening off the steroids. In the beginning I experienced migraines, which I never had before, about 2 per week, Now about 1 per month. I also regularly experience diarrhea, not having to go more often, but lose stool when I do. Annoying but tolerable. It also seems to work as an appetite suppressant, which is positive side effect for me at 40 yrs old lost about 8 lbs so far. So overall pretty good med now that migraines are less."

   
8.0

activatedvoxel July 7, 2017

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"Was on Otezla for 4 months. Absolutely no improvement, and side effects were dreadful...splitting migraine headaches daily, chronic diarrhea, depression. I would never consider taking this medication again."

   
1.0

Neal C. (taken for 1 to 6 months) June 15, 2017

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"I have been taking otezla for five months with no improvement in my psoriatic arthritis. I had minor psoriasis plaques on my elbows. It is definitely clearer. My joints have shown no improvement. I have lost a considerable amount of weight while on otezla and am now quite underweight. I will have to discontinue the drug because of the weight loss and the fact that it has done nothing for the arthritis."

spareribs (taken for 1 to 6 months) June 10, 2017

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"8 days in. No relief and as the Enbrel I was taking wears off I am hurting so bad I had to start a course of prednisone. I feel nauseous and depressed. Beautiful weather outside and I don't care. I'm in a farm room watching TV. Miserable and not myself. Called my doctor so we will see what he says to do. I may follow up this post with further results. To be fair it's only Day 8 maybe it will improve"

Unity659 June 1, 2017

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"I have been on Otezla for 2 months now and have experienced a remarkable clearing of my lesions. Both knees, which were 90% affected have almost entirely cleared up. The face lesions have dried up and are almost unnoticeable now. The scalp, which was almost completely affected, has cleared up to the point that I'll soon be getting rid of the ever-present ball cap! (YES!!!) I feel that in one month, at my follow up appointment with my dermatologist, I am going to kiss her smack dab on the lips! My Wife has given me permission. Still haven't noticed a pronounced difference in my two thumbs, which have swollen at the joint over the last year or so. Hopefully, they will get better as well so I can get back to playing the guitar."

   
10

Shadowfax419 (taken for 1 to 6 months) April 8, 2017

15 users found this comment helpful.
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"Have been taking this for almost 2 years now. For me, it works great. Had some of the side effects initially - nausea, lack of appetite, headaches and loose stools. But all of those side effects are gone now. I have had almost NO PSA flares and my blood work is absolutely perfect. Everyone is different, but for me right now, and for the past 2 years, this drug has been fantastic."

   
10

OtezlaFan (taken for 2 to 5 years) March 24, 2017

24 users found this comment helpful.
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"I have been taking Otezla for about 8 weeks. I experienced nausea, frequent bowel movements, headaches, and a lack of appetite although the severity tapered off after a few weeks, they still continue. As I did more research into others who have taken it I have experienced 2 trips to the ER due to inflammation in my feet and I feel so fatigued and don't want to do anything...but I feel better if I move around a bit...but I get wore out pretty easy and then my feet are killing me. I'd like to say I feel better than when I started... and in some ways I do. I used to feel like my joints were fusing together, I couldn't walk up or down stairs, and I couldn't open a bottle of water. I feel a lot looser now and can do some things. I still hurt."

   
4.0

Huck321 January 3, 2017

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"So it's been 2 months now..I have been self controlling a little as I had a headache from hell.. only two times tho.. so why it's random I do not understand.. but it's so bad I can't touch it with 10 Tylenol.. it's crippling. BUT.. even so..I hate psoriasis so bad.. my life is altered by it..I continued on the Otezla with half the dose for a while.. back to full dosage.. but my psoriasis had returned due to the reduced dosage.. hoping it goes away again and those headaches as well.. nothing else is troubling.. the headaches need to subside so I can function normally at life and my job!"

   
7.0

Margot928 November 15, 2016

11 users found this comment helpful.
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"I have mod/severe RA overlapping with PSA. I developed a worsening of Psoriasis on Humira. I stopped Humira and DR wanted me to try Otezla to clear my Psoriasis. I can say this is the worst drug i have ever taken. I had a severe migraine for 5 days. I had very low energy levels, loss of appetite and nausea. I also developed really bad spasms. I took Methotrexate for 5 years and didn't feel this bad. I stopped Otezla going back to Humira and Methotrexate... I hope!"

   
1.0

RLT (taken for less than 1 month) November 11, 2016

15 users found this comment helpful.
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