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User Reviews for Otezla

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Otezla Rating Summary

User Ratings
10
   
17%(14)
9
   
10%(8)
8
   
6%(5)
7
   
8%(6)
6
   
6%(5)
5
   
12%(10)
4
   
10%(8)
3
   
9%(7)
2
   
9%(7)
1
   
18%(15)
5.4/10 Average Rating
85 Ratings with 89 User Reviews

What next? Compare all 54 medications used in the treatment of Psoriatic Arthritis.

Reviews for Otezla to treat Psoriatic Arthritis

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"I’ve been on Otezla for almost 6 weeks for psoriatic arthritis. It improved my psoriasis almost immediately, but then the change slowed way down. No patches have totally cleared yet, though they do look better. No noticeable effect on pain yet. Unfortunately, the GI side effects seem to be getting worse instead of better, to the point where I don’t want to eat anything. I’m also consistently having headaches and increased fatigue. I’m going to try taking only one pill a day, but if that doesn’t get the side effects to a manageable level, I’ll have to stop."

   
5.0

Anonymous (taken for 1 to 6 months) November 14, 2018

1 users found this comment helpful.
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"My dr put me on Otezla for psoriatic arthritis over a year ago. The results were absolutely amazing! I had terrible itchy, scaly patches on my scalp and all in and outside of my ears. Also had a lot of joint pain. This drug eliminated all of that PLUS I lost 45 lbs. Now, it did cause diarrhea, but it wasn't unmanageable. I felt better than I have felt in years. I was lucky at that time to get this for a zero co-pay and stayed on it for a year. Unfortunately, I went on medicare this year and am no longer eligible for the zero copay and now my co-pay will be over $1,200/month, which I cannot possibly afford. I am heartbroken and all broken out again after getting off of it (plus gaining some of the weight back). I wish the drug manufacturer could somehow reduce the cost so it would be more affordable. Hopefully as time goes by, they will. But, if you can get it, please try it. I know you will be pleased."

   
9.0

Liza (taken for 1 to 2 years) October 19, 2018

5 users found this comment helpful.
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"My dermatologist put me on Otezla for Granuloma Annulare. Mine is rare in that it is widespread and "recalcitrant." I have been on it for almost 2 weeks now. I have nausea and bathroom urgency throughout the day, though it is lessening as the days go by. I have not yet reached to full dose as I was instructed to take a dose only on a full stomach and I am too nauseous to eat two large meals a day. So I'm up to 30 mg once a day. The headaches have mostly subsided so it gives me hope that I will get acclimated to the other side effects. However I am so uncomfortable and full of aches and pains and exhaustion that I can't tell if I'm depressed or not! I sure don't feel like doing anything at all. So time will tell. I revisit the derm at 5 weeks. So far, I have not noticed any changes in my GA lesions."

GAgirl (taken for less than 1 month) October 13, 2018

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"I've been taking Otezla since June 29th 2018. I was prescribed Otezla by the dermatologist but plaque was not present just dry skin. A small small patch of dry skin on my arm prompted a biopsy and that's how I got my Psoriatic arthritis diagnosis. My issue is I do not and never had any plaque skin issues just joint pain and I don't find this medication handling the joint pain on a daily basis. Every so often I'll get a severe pain in a finger joint, a bone in my foot or shoulder pain. I'm not sure if I need to continue taking this. I also have osteoarthritis have had knee replacement and now was told I need hip replacement. I'm going to give this medication one more month and see what the outcome will be. One good thing is I had no side effects at all."

   
5.0

Mimi (taken for 1 to 6 months) September 19, 2018

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"Rashes in crotch area for at least 5 years. Rash on chest for decades. Acne for 55 years. Scaly patches on arms, legs, back for 10-15 years. Pitted dry fingernails for 30 years. Dry eyes, dry mouth. Dupuytren’s Contracture for several- maybe 5-10 years. Lower back pain for over 40 years. Severed shoulder tendon. Both Achilles Tendons sore. In the past 40 years only have had 2 or 3 pain free days. I have read 4 pages of reviews. My heart goes out to you all. To us all. This is an unpredictable disease. Yesterday was day 4, 20mg + 20 mg and I had marked relief in hand and finger pain. Although swelling has not abated. I had a mild and short-lived headache, and mild but longer lived stomach pain. Today I awoke with more swelling in my fingers than ever, painful- but not more pain than ever. I took 20mg + 30 mg today. Swelling and pain both decreasing as the day wears on. Mild stomach pain - short lived. Stronger and longer headaches, but easily tolerable."

   
10

GoSox1 August 7, 2018

8 users found this comment helpful.
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"I had very mild psoriasis and Psoriatic arthritis and was put on Humira about 10 years ago. I thought I might have been in remission so I stopped. After 18 months, I finally went back to the Dr and she suggested Otezla. I started otezla about 11 weeks ago. I only had mild stomach issues. I wanted to lose weight so that side effect was welcome (lost 20lb), I found my appetite was greatly reduced. 5 weeks in my joint pain was getting better but I developed the worst upper respiratory problem that I ever had. I do not get sick typically - even while on Humira. It was really bad for about a week but it is now 5 weeks into this upper respiratory issue and it continues to linger - I'm taking both Sudafed and Mucinex dm so the symptoms are milder (a mild cough, ears plug up off and on). I have not read many people who had upper respiratory reactions. I still have about 3 weeks until I reach the full efficacy point so I think I will stick it out for the time being."

   
7.0

john_r July 19, 2018

11 users found this comment helpful.
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"I have been on otezla for only a month it has taken the pain from my fingers and elbows away. It is starting to work on my plaque psoriaisis I have had psoriasis for 56 years. I'm 73 now otezla is working the best out of anything else I have tried. I had very few side affects just a little nausea not much I sure hope it keeps working"

   
6.0

rml313 (taken for 1 to 6 months) June 18, 2018

7 users found this comment helpful.
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"From the start I had joint pain. I needed a couple of advil every day. The stiffness is slowly increasing also. It's been 5 months. We are now going to try something else. I go to the bathroom 3 times a day. My stomach is very upset after taking the pill for 3 hours. My stomach is getting worse. I have a yogurt everyday and avoid disruptive foods. My teeth hurt. At first they woke me up during the nite and I had to have advil for the pain. Now it is mild a couple times a week. My psoriasis has completely disappeared thats the good."

   
3.0

CHANCE (taken for 1 to 6 months) June 10, 2018

5 users found this comment helpful.
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"Coming off enbrel after 14 years I had numerous bouts with kidney stones. Then most recently last year I had numerous blood clots in the leg I gave myself shots in. Asked my PA about any other drugs. He suggested Otezla. I have been on it for 3 months and my legs feet toes ankles and Achilles ligaments have continually been in pain switching from day to day and am currently barely able to walk. I am a very good bowler and bowl in highly competitive competitions. I have gotten to the competition and couldn't even move . I never know from day to day if I will be able to compete or not. It costs hundreds of dollars to compete and I have not even come close to being competitive at any . I have had to withdraw from some because of the pain I'm in."

   
6.0

Dennis (taken for 1 to 6 months) May 6, 2018

6 users found this comment helpful.
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"I am considering Otezla for my Psoriatic Arthritis, but after reading these reviews I wanted to share something that some of you may find helpful. There is a book entitled "The Great Arthritis Breakthrough" in which the author cites several studies that have attributed many cases of arthritis to bacteria and tests confirmed that a daily low dose of Minocycline antibiotic fended off the arthritis. I tried this regimen and found that it did work great for arthritis, however it did nothing for the Psoriasis. But seriously, if you are in pain like I was, this is worth it. I took Minocycline for about 2 years and then stopped and have have been off of it for two years now. I am only now starting to have a little inflammation in my right middle finger. Anyway, I wanted to share this in case others might find it useful."

davegerard (taken for less than 1 month) April 16, 2018

17 users found this comment helpful.
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"Though I had no side effects when taking other biologics - or any meds - I had terrible respiratory stuff while on this so went off after a week or so. The way they tested it didn't allow me to know what to expect as they seemed they have data only at a 4 month or so mark. I wouldn't recommend it."

   
1.0

syb March 29, 2018

3 users found this comment helpful.
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"I took this drug for 11 months and finally had to come off it. From Feb to May I did notice an improvement with pain but in June my hands and feet had such nerve pain I could hardly walk and had trouble planting my little garden. I was told the nerve pain could not be from Otezla. From day one I had 2 hours with diarrhea and was told that too would pass. It didn't. I stopped the drug in December before Christmas and the nerve pain and diarrhea completely stopped. Mind you I still have sore feet and hands but feel so comfortable. I had been on Methtrexate and Humira before this drug and they too had massive problems. I have always had Irritable bowel syndrome (IBS) but now my Surgeon said it was undiagnosed diverticulitis that I had kept controlled by diet. These drugs made my bowel much worse and now I need a section removed. How sad is that. Is there even a good drug out there?"

   
3.0

Bridget (taken for 6 months to 1 year) March 25, 2018

1 users found this comment helpful.
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"I have had psoriasis and pasoriatic arthritis for the 10 years. I have tried all kinds of creams nothing has helped. Until this pill! OMG I'm completely amazed of how much my psoriatic arthritis has gone with this pill. I would cry every day with pain of the joints . The pain I would have in my neck was soooo bad. This is a amazing pill and everyone should try it. Form my psoriasis it has helped some but for my psoratic arthoritis it has been amazing plus do the 0 copay bc my insurance wanted $3500 a month and I couldn't do that at all. Thanks so much for this pill!!It literally has saved my life with pain daily!!"

   
7.0

nea (taken for 1 to 6 months) March 16, 2018

13 users found this comment helpful.
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"I have been on Otezla going on my 4th year I had plaque psoriasis and swelling of joints I was nauseous for maybe 2 weeks when I started, my ring finger was a size nine and now it’s a size five that’s how much swelling has gone down for me. All my plaque was completely gone by the 3rd month which included my whole head my ears and unmentionable parts! I don’t have depression or any other side affects for me this drug is amazing!"

   
10

Trista7777 (taken for 2 to 5 years) February 26, 2018

11 users found this comment helpful.
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"When ointments are not as effective as they used to be, I started researching other treatments for Psoriasis. It's a constant battle on my head and wearing black is becoming more difficult. I'm not considering injection therapy so Otezla seemed the perfect solution. Side effects began on day 2 and started to subside after 2 weeks. However, the tension headaches got worse and I stopped treatment after 2 1/2 weeks. I saw little impact on my psoriasis, but I probably didn't take it long enough. However, my Psoriatic Arthritis was completely gone, which of course is acting up again. I so wished this would have worked for me."

   
5.0

Hausfrau (taken for less than 1 month) February 24, 2018

3 users found this comment helpful.
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"Was prescribed and took for 8 months for plaque psoriasis and psoriatic arthritis. After a month began to notice a big reduction in plaques but only mild relief in pain. After 4 months began to experience depressed feelings and random dark thoughts while nothing had changed in life circumstances. Decided to go off when scared myself with thoughts of crashing my vehicle while driving. However, be warned the psoriasis plaques is worse now than before I took the meds and the joint pain is back. Would not recommend."

   
3.0

StillSuffering478 February 18, 2018

5 users found this comment helpful.
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"I have now been taking Otezla for 2 years. I have never had bad psoriasis, but psoriatic arthritis has affected me for about 5 years. It took me almost 9 months for my psoriatic arthritis saw any improvement. After 1 year of taking, I thought it was a wonder drug. I have had constant stomach and headache issues that I was willing to accept. I figured it wasn't as bad as having PsA. About 6 months ago it stopped working for me. I started experiencing pretty bad moods and felt like I was falling into depression. I have since moved on to a single dose at bed time. I recently started using CBD oil and it seems to be working pretty well. Worked for a while, but side effects were almost as bad as the condition."

   
4.0

Middleman12345 (taken for 2 to 5 years) January 17, 2018

9 users found this comment helpful.
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"I was prescribed Otezla for psoriatic arthritis. I took it for about 18 weeks. My arthritis improved only minimally. - I experienced the side effects of nausea, diarrhea and headaches throughout the 18 weeks. I stopped the treatment since it wasn't really working for me. And that is where the real trouble began - I had only suffered mild psoriasis over the years. I have not had a significant outbreak in over 25 years. In very short order, after I stopped this medicine, my psoriasis returned with a vengeance!! It's now almost 6 months since I've stopped taking this drug and I'm STILL trying to get the psoriasis under control. I would NOT recommend anyone take this drug."

   
2.0

HodaMac December 18, 2017

8 users found this comment helpful.
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"I have been taking Otezla for psoriatic arthritis as well as psoriasis. At first I thought it was a miracle drug helping with the pain and the patches. I did have terrible (and I mean terrible) problems with my stomach. While it improved slightly, after a year and a half it still kills my stomach. I am going to get off of it because it stopped helping with the pain and my skin is worsening. I stuck with it despite the nonstop bowel movements (and headaches) because I thought it was helping, but now that I'm reverting back it isn't worth the nearly debilitating side effects."

Anonymous (taken for 1 to 2 years) November 30, 2017

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"I was diagnosed with HLA-B27 (a specific protein on your white blood cells that can be a sign of autoimmune disease) Dr told me I had Psoriatic Arthritis gave me a starter pack of Otezla took for 12 days , which all of stiffness and joint pain left, I am also on Phentermine and Topimirate for weight loss, so I didn’t experience any headache, however I did get somewhat depressed and no energy to do anything, I ran out of the starter pack had to get another but was off of it for 3 days, while off of it I noticed my mood was better and back to normal, but this morning oh my all my stiffness and pain are back so I am goin back on the new starter pack and try to deal with mood thing because this pain is crazy, I also do have a sinus head cold that I have had for 4 days but I kinda chalked that off to the time of year and weather!"

   
7.0

Kandi313 (taken for less than 1 month) November 13, 2017

7 users found this comment helpful.
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"Been on Otezzla for about 6 months. The first few months I thought my prayers had been answered. My skin cleared up by 75 percent in 3 months. I have psoriasis and psoriatic arthritis. My pain had decreased as well. I did have stomach issues, severe headaches and major pressure in my ears and can hardly hear! The medication has quit working. Not clearing up my scales or itching at all! And the pain! The pain in my fingers, elbows and feet is worse than ever. I'm up all during the night from joint pain, now have nerve pain in my feet and cannot open a bottle of water in the mornings. Very sad this didn't work out because I refuse to take immune suppression medication."

   
5.0

Denny789824 September 17, 2017

6 users found this comment helpful.
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"On otezla for a short time 4 weeks must come off it because of surgery right shoulder rotator cuff. Up to this point minor side effects but did cause some sleep issues which could also be contributed my upcoming surgery. Had such good results with Biologicals for 15 yrs. until they lost there effectiveness. Now as I get older 67 would like to try something less immunosuppressive. Not encouraged by comments I read. But everyone is different so I will stick it out for four months"

   
4.0

Mattcat (taken for 1 to 6 months) September 12, 2017

6 users found this comment helpful.
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"I took Otezla twice, two years apart. My first experience helped my psoriasis and psoriatic arthritis within 3 months with minimal side effects. I had loose stool for a couple of days and a mild headache. THEN I developed a very aggressive breast cancer and was advised to stop Otezla.. I underwent chemotherapy, bilateral mastectomies and reconstruction. One year later, I began taking Otezla again because my psoriasis and PA came back with a vengeance, as predicted. Four months into treatment, I developed breast cancer in my sternum. Once again, I quit the Otezla and have since undergone radiation treatment. I did not tick the boxes for a patient at high risk for breast cancer. I feel my cancer may well have been a direct result of Otezla"

   
1.0

Joschally September 1, 2017

12 users found this comment helpful.
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"I took otezla for about 5 months for psoriatic arthritis. I experienced headaches and upper respiratory infections almost the entire time. I saw little, if any, improvement to my arthritis pain and inflammation."

   
1.0

Yandy (taken for 1 to 6 months) August 1, 2017

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"Since the first pill on Otezla I started to get severe sinus headaches that could not be remedied by Tylenol or Advil. Nasal congestion began shortly after that as did steady head pain. I am now 7 days on the pills and I stopping due to these headaches, loose bowel movements, sinus congestion and pain, headaches and most importantly INSOMNIA!! I have been up 2 days straight and have stopped these pills last night. Since being on these pills I have not slept more than 2 hrs per night if at all. My foot pain has been lessened as well as the pain in my fingers but the side effects are just not worth it. Still getting sharp pains in my toes and difficulty with hip joint and knees while I did not have before starting Otezla. Not the drug for me!"

cdep July 23, 2017

17 users found this comment helpful.
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