User Reviews for Otezla to treat Psoriatic Arthritis (Page 2)
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Reviews for Otezla
"I have now been taking Otezla for 2 years. I have never had bad psoriasis, but psoriatic arthritis has affected me for about 5 years. It took me almost 9 months for my psoriatic arthritis saw any improvement. After 1 year of taking, I thought it was a wonder drug. I have had constant stomach and headache issues that I was willing to accept. I figured it wasn't as bad as having PsA. About 6 months ago it stopped working for me. I started experiencing pretty bad moods and felt like I was falling into depression. I have since moved on to a single dose at bed time. I recently started using CBD oil and it seems to be working pretty well. Worked for a while, but side effects were almost as bad as the condition."
"I was prescribed Otezla for psoriatic arthritis. I took it for about 18 weeks. My arthritis improved only minimally. - I experienced the side effects of nausea, diarrhea and headaches throughout the 18 weeks. I stopped the treatment since it wasn't really working for me. And that is where the real trouble began - I had only suffered mild psoriasis over the years. I have not had a significant outbreak in over 25 years. In very short order, after I stopped this medicine, my psoriasis returned with a vengeance!! It's now almost 6 months since I've stopped taking this drug and I'm STILL trying to get the psoriasis under control. I would NOT recommend anyone take this drug."
"I have been taking Otezla for psoriatic arthritis as well as psoriasis. At first I thought it was a miracle drug helping with the pain and the patches. I did have terrible (and I mean terrible) problems with my stomach. While it improved slightly, after a year and a half it still kills my stomach. I am going to get off of it because it stopped helping with the pain and my skin is worsening. I stuck with it despite the nonstop bowel movements (and headaches) because I thought it was helping, but now that I'm reverting back it isn't worth the nearly debilitating side effects."
"I was diagnosed with HLA-B27 (a specific protein on your white blood cells that can be a sign of autoimmune disease) Dr told me I had Psoriatic Arthritis gave me a starter pack of Otezla took for 12 days , which all of stiffness and joint pain left, I am also on Phentermine and Topimirate for weight loss, so I didn’t experience any headache, however I did get somewhat depressed and no energy to do anything, I ran out of the starter pack had to get another but was off of it for 3 days, while off of it I noticed my mood was better and back to normal, but this morning oh my all my stiffness and pain are back so I am goin back on the new starter pack and try to deal with mood thing because this pain is crazy, I also do have a sinus head cold that I have had for 4 days but I kinda chalked that off to the time of year and weather!"
"Been on Otezzla for about 6 months. The first few months I thought my prayers had been answered. My skin cleared up by 75 percent in 3 months. I have psoriasis and psoriatic arthritis. My pain had decreased as well. I did have stomach issues, severe headaches and major pressure in my ears and can hardly hear! The medication has quit working. Not clearing up my scales or itching at all! And the pain! The pain in my fingers, elbows and feet is worse than ever. I'm up all during the night from joint pain, now have nerve pain in my feet and cannot open a bottle of water in the mornings. Very sad this didn't work out because I refuse to take immune suppression medication."
"On otezla for a short time 4 weeks must come off it because of surgery right shoulder rotator cuff. Up to this point minor side effects but did cause some sleep issues which could also be contributed my upcoming surgery. Had such good results with Biologicals for 15 yrs. until they lost there effectiveness. Now as I get older 67 would like to try something less immunosuppressive. Not encouraged by comments I read. But everyone is different so I will stick it out for four months"
"I took Otezla twice, two years apart. My first experience helped my psoriasis and psoriatic arthritis within 3 months with minimal side effects. I had loose stool for a couple of days and a mild headache. THEN I developed a very aggressive breast cancer and was advised to stop Otezla.. I underwent chemotherapy, bilateral mastectomies and reconstruction. One year later, I began taking Otezla again because my psoriasis and PA came back with a vengeance, as predicted. Four months into treatment, I developed breast cancer in my sternum. Once again, I quit the Otezla and have since undergone radiation treatment. I did not tick the boxes for a patient at high risk for breast cancer. I feel my cancer may well have been a direct result of Otezla"
"I took otezla for about 5 months for psoriatic arthritis. I experienced headaches and upper respiratory infections almost the entire time. I saw little, if any, improvement to my arthritis pain and inflammation."
"Since the first pill on Otezla I started to get severe sinus headaches that could not be remedied by Tylenol or Advil. Nasal congestion began shortly after that as did steady head pain. I am now 7 days on the pills and I stopping due to these headaches, loose bowel movements, sinus congestion and pain, headaches and most importantly INSOMNIA!! I have been up 2 days straight and have stopped these pills last night. Since being on these pills I have not slept more than 2 hrs per night if at all. My foot pain has been lessened as well as the pain in my fingers but the side effects are just not worth it. Still getting sharp pains in my toes and difficulty with hip joint and knees while I did not have before starting Otezla. Not the drug for me!"
"I am technically taking this for reactive arthritis, that I have struggled with on and off for 15 years. Most recently on a 4 year stint, where I have been talking steroids. The idea was that this would allow me to get off of steroids. It took a few months to seem to help, but now (6 months) I have been weening off the steroids. In the beginning I experienced migraines, which I never had before, about 2 per week, Now about 1 per month. I also regularly experience diarrhea, not having to go more often, but lose stool when I do. Annoying but tolerable. It also seems to work as an appetite suppressant, which is positive side effect for me at 40 yrs old lost about 8 lbs so far. So overall pretty good med now that migraines are less."
"Was on Otezla for 4 months. Absolutely no improvement, and side effects were dreadful...splitting migraine headaches daily, chronic diarrhea, depression. I would never consider taking this medication again."
"I have been taking otezla for five months with no improvement in my psoriatic arthritis. I had minor psoriasis plaques on my elbows. It is definitely clearer. My joints have shown no improvement. I have lost a considerable amount of weight while on otezla and am now quite underweight. I will have to discontinue the drug because of the weight loss and the fact that it has done nothing for the arthritis."
"8 days in. No relief and as the Enbrel I was taking wears off I am hurting so bad I had to start a course of prednisone. I feel nauseous and depressed. Beautiful weather outside and I don't care. I'm in a farm room watching TV. Miserable and not myself. Called my doctor so we will see what he says to do. I may follow up this post with further results. To be fair it's only Day 8 maybe it will improve"
"I have been on Otezla for 2 months now and have experienced a remarkable clearing of my lesions. Both knees, which were 90% affected have almost entirely cleared up. The face lesions have dried up and are almost unnoticeable now. The scalp, which was almost completely affected, has cleared up to the point that I'll soon be getting rid of the ever-present ball cap! (YES!!!) I feel that in one month, at my follow up appointment with my dermatologist, I am going to kiss her smack dab on the lips! My Wife has given me permission. Still haven't noticed a pronounced difference in my two thumbs, which have swollen at the joint over the last year or so. Hopefully, they will get better as well so I can get back to playing the guitar."
"Have been taking this for almost 2 years now. For me, it works great. Had some of the side effects initially - nausea, lack of appetite, headaches and loose stools. But all of those side effects are gone now. I have had almost NO PSA flares and my blood work is absolutely perfect. Everyone is different, but for me right now, and for the past 2 years, this drug has been fantastic."
"I have been taking Otezla for about 8 weeks. I experienced nausea, frequent bowel movements, headaches, and a lack of appetite although the severity tapered off after a few weeks, they still continue. As I did more research into others who have taken it I have experienced 2 trips to the ER due to inflammation in my feet and I feel so fatigued and don't want to do anything...but I feel better if I move around a bit...but I get wore out pretty easy and then my feet are killing me. I'd like to say I feel better than when I started... and in some ways I do. I used to feel like my joints were fusing together, I couldn't walk up or down stairs, and I couldn't open a bottle of water. I feel a lot looser now and can do some things. I still hurt."
"So it's been 2 months now..I have been self controlling a little as I had a headache from hell.. only two times tho.. so why it's random I do not understand.. but it's so bad I can't touch it with 10 Tylenol.. it's crippling. BUT.. even so..I hate psoriasis so bad.. my life is altered by it..I continued on the Otezla with half the dose for a while.. back to full dosage.. but my psoriasis had returned due to the reduced dosage.. hoping it goes away again and those headaches as well.. nothing else is troubling.. the headaches need to subside so I can function normally at life and my job!"
"I have mod/severe RA overlapping with PSA. I developed a worsening of Psoriasis on Humira. I stopped Humira and DR wanted me to try Otezla to clear my Psoriasis. I can say this is the worst drug i have ever taken. I had a severe migraine for 5 days. I had very low energy levels, loss of appetite and nausea. I also developed really bad spasms. I took Methotrexate for 5 years and didn't feel this bad. I stopped Otezla going back to Humira and Methotrexate... I hope!"
"I have been taking this medication for a little over 2 months for scalp psoriasis and psoriatic arthritis. I have been lucky and experienced no adverse side effects except for several minutes of minor nausea during the first week or so of beginning it. My scalp cleared almost completely within 2-3 weeks. The itchiness is gone as well. The swelling in my hands has decreased about 20 to 25 percent and I am hoping for more as I reach the 4 to 5 month mark. I was able to remove a ring that I was sure would need to be cut off. I also have had no other side effects that others have reportedsuch as mood changes, headache, diarrhea, etc. I want others to know about good experiences so they won't be scared off. I will report back soon."
"Started taking otezla 12 days ago. I have experienced headache, nausea, fatigue, swollen and painful joints, upper right abdominal pain, swollen belly on the right side, feet pain, back pain, mild diarrhea, no ambition, hoarsness, light colored stools. I still have to take indomethician for joint inflammation and pain. I thought this drug would relieve my pain and prevent inflammation and further joint damage, instead it has made it worse. I don't see the advantage of continuing to use it along with an anti-inflammatory drug. I might as well stick with indomethicin."
"When I started otezla, I was having moderate arthritis affects. Right away I had head and neck pain. Throughout the 4 months I was on it, I lost 10 lbs, no appetite, nausea, bad flu flares, sometimes rapid heartbeat and no discernable relief. At 4 month mark I experienced a massive spasming of my scalp and neck muscles. As in tetany. You need your neck to sit up, lay down, walk, drive..I couldn't do anything. I like to think my pain threshold is high, but this brought me to my knees. I've been on more Prednisone with otezla then ever before..just to counteract all the flares, tendon pain. I'm off otezla now for 4 days, and still cannot move my neck properly. I hope with time it goes away. No benefits, lots of aggravation. Not a good med for"
"I started this in March, by The end of Aug this med stopped working. It did a pretty good job of clearing up the Psorisis but my joint pain is thru the roof. My hands are progressively getting worse. It doesn't touch my RA. Instead of taking me off of it my Rheumy added MTX which I don't tolerate well. So I'm taking myself off. I got so bloated, and gassy thru the starter pack. I GAINED 20lbs! Not sure if it's the med or my increase in pain has me sidelined. I currently have tons of congestion which I have had for 3 months! DONE WITH THIS STUFF ,"
"It is hard for me to rate this. I have Psoriasis and psoriatic arthritis. I have been taking Otezla for 9 months now. Within weeks my severe psoriasis had cleared. However, my arthritis is worse. At first, it seemed to stop the swelling a little. I have to say it was about 5 months before all the swelling and severe pain came back. While the pain was never completely gone, it was never this bad. Not even before Otezla. My muscles in the back of my legs hurt, and on the bottom of my right foot. I am having trouble walking. I also take hydrocodone for pain. I was taking the hydrocodone for two years and was hoping to get off with Otezla. Not going to happen. Has anybody had dental problems. I have had 3 teeth crack in the past 6 months."
"had flu like body aches, constant urge to defecate and brutal migraines from day 3. fatigue was all consuming. rather deal with the joint pain!!"
"My dermatologist put me on this medication using starter packs while they worked with the insurance to approve it. I lost my appetite completely I was exhausted, I almost lost my hearing and I got a serious upper respiratory infection. I had constant diarrhea and nausea and practically no sleep. I had to quit when I got the respiratory infection as I could hardly breathe. Why on earth is more testing not done with these drugs. The pharmaceutical companies churn our arthritis medication one after the other all of them with horrible side affects and outrageous pricing. How dare they try to charge almost $3000 a month for a drug with such poor results. Back to methotrexate and ibuprofen at least I can afford them."
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