Otezla Alternatives Compared
Otezla | Sotyktu | Skyrizi |
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Otezla (apremilast) | Sotyktu (deucravacitinib) | Skyrizi (risankizumab) |
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Prescription only
Otezla is a PDE4 inhibitor that may be used to treat adults with plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet’s Disease. It may also be used to treat plaque psoriasis... View more |
Prescription only
Prescribed for Plaque Psoriasis. Sotyktu may also be used for purposes not listed in this medication guide. |
Prescription only
Skyrizi is an interleukin inhibitor that may be used to treat adults with plaque psoriasis, psoriatic arthritis, Crohn's disease, or ulcerative colitis (UC). The usual dosage is 150mg every 12 weeks... View more |
Related suggestions |
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More about Otezla (apremilast) | More about Sotyktu (deucravacitinib) | More about Skyrizi (risankizumab) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Otezla has an average rating of 5.1 out of 10 from a total of 436 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 41% reported a negative effect. |
Sotyktu has an average rating of 5.1 out of 10 from a total of 7 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 43% reported a negative effect. |
Skyrizi has an average rating of 7.8 out of 10 from a total of 42 ratings on Drugs.com. 72% of reviewers reported a positive effect, while 18% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Otezla side effects in more detail. |
See also: Sotyktu side effects in more detail. |
See also: Skyrizi side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
N/A |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Otezla prices |
View all Sotyktu prices |
View all Skyrizi prices |
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Dosage Forms Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
9 hours |
10 hours |
672 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 87 drugs are known to interact with Otezla:
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A total of 468 drugs are known to interact with Sotyktu:
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A total of 171 drugs are known to interact with Skyrizi:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
March 21, 2014 |
September 09, 2022 |
N/A |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.