Otezla Alternatives Compared
| Otezla Remove Otezla from your drug comparison | Humira Remove Humira from your drug comparison | Enbrel Remove Enbrel from your drug comparison |
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| Otezla apremilast Remove Otezla from your drug comparison | Humira adalimumab Remove Humira from your drug comparison | Enbrel etanercept Remove Enbrel from your drug comparison | ||||||||||||||||||||||||
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Otezla is a PDE4 inhibitor that may be used to treat plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet’s Disease. It has been associated with severe diarrhea, nausea, and v... View more |
Humira is a TNF-alfa inhibitor that may be used to treat a wide range of different inflammatory conditions, such as Rheumatoid Arthritis, psoriasis, ankylosing spondylitis, Crohn's disease, and... View more |
Enbrel is a subcutaneous injection that is usually self-administered once or twice a week for inflammatory conditions such as rheumatoid arthritis, psoriasis, psoriatic arthritis, or ankylosing... View more |
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Prescription only |
Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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Common side effects include: weight loss. See the full Otezla side effects document. |
Common side effects include: upper respiratory tract infection, headache, injection site reaction, skin rash, antibody development, sinusitis, pain at injection site. See the full Humira side effects document. |
Common side effects include: infection, injection site reaction. See the full Enbrel side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Otezla prices |
View all Humira prices |
View all Enbrel prices |
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Generic Availability |
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No |
No |
No |
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Dosage Form(s) Available |
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Brand Names |
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N/A |
Other adalimumab brands include: Abrilada, Amjevita, Cyltezo, Hadlima, Hulio, Hyrimoz | Other etanercept brands include: Erelzi, Eticovo | ||||||||||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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9 hours |
480 hours |
300 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
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Drug Interactions |
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A total of 69 drugs are known to interact with Otezla:
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A total of 397 drugs are known to interact with Humira:
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A total of 397 drugs are known to interact with Enbrel:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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March 21, 2014 |
December 31, 2002 |
November 02, 1998 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.