Otezla Alternatives Compared
| Otezla | Humira | Taltz |
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| Otezla (apremilast) | Humira (adalimumab) | Taltz (ixekizumab) |
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Prescription only
Otezla is a PDE4 inhibitor that may be used to treat plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet’s Disease. It has been associated with severe diarrhea, nausea, and v... View more |
Prescription only
Humira is a TNF-alfa inhibitor that may be used to treat a wide range of different inflammatory conditions, such as Rheumatoid Arthritis, psoriasis, ankylosing spondylitis, Crohn's disease, and... View more |
Prescription only
Taltz is a monoclonal antibody that reduces inflammation and may be used to treat conditions such as psoriasis, psoriatic arthritis, or ankylosing spondylitis. It is given by injection just under the... View more |
Related suggestions Psoriatic Arthritis
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| More about Otezla (apremilast) | More about Humira (adalimumab) | More about Taltz (ixekizumab) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Otezla has an average rating of 5.1 out of 10 from a total of 404 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 42% reported a negative effect. |
Humira has an average rating of 6.3 out of 10 from a total of 643 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 32% reported a negative effect. |
Taltz has an average rating of 6.9 out of 10 from a total of 168 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 24% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Common side effects include:
See also: Otezla side effects in more detail. |
Common side effects include:
See also: Humira side effects in more detail. |
See also: Taltz side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Otezla prices |
View all Humira prices and generic prices |
View all Taltz prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
Other adalimumab brands include: Abrilada, Amjevita, Cyltezo, Hadlima, Hulio, Hyrimoz, Yusimry |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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9 hours |
480 hours |
312 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 75 drugs are known to interact with Otezla:
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A total of 426 drugs are known to interact with Humira:
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A total of 193 drugs are known to interact with Taltz:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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March 21, 2014 |
December 31, 2002 |
March 22, 2016 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.