Comparing Methotrexate vs Otezla
| Methotrexate Remove Methotrexate from your drug comparison | Otezla Remove Otezla from your drug comparison |
|---|
| Methotrexate Remove Methotrexate from your drug comparison | Otezla apremilast Remove Otezla from your drug comparison | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
Otezla is a PDE4 inhibitor that may be used to treat plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet’s Disease. It has been associated with severe diarrhea, nausea, and v... View more |
||||||||||||||||
|
Prescription only |
Prescription only |
||||||||||||||||
Ratings & Reviews |
|||||||||||||||||
Drug Class |
|||||||||||||||||
Side Effects |
|||||||||||||||||
|
Commonly reported side effects include: increased liver enzymes. See the full methotrexate side effects document. |
Common side effects include: weight loss. See the full Otezla side effects document. |
||||||||||||||||
Pricing and Coupons* Prices are without insurance |
|||||||||||||||||
View all methotrexate prices |
View all Otezla prices |
||||||||||||||||
Generic Availability |
|||||||||||||||||
|
Yes (this medicine) |
No |
||||||||||||||||
Dosage Form(s) Available |
|||||||||||||||||
|
|
||||||||||||||||
Brand Names |
|||||||||||||||||
| Methotrexate LPF Sodium, Otrexup, Rasuvo, RediTrex, Trexall, Xatmep |
N/A |
||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
|||||||||||||||||
|
12 hours |
9 hours |
||||||||||||||||
CSA Schedule**View glossary of terms. |
|||||||||||||||||
|
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
||||||||||||||||
Pregnancy Category |
|||||||||||||||||
|
Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
||||||||||||||||
Drug Interactions |
|||||||||||||||||
|
A total of 605 drugs are known to interact with methotrexate:
|
A total of 71 drugs are known to interact with Otezla:
|
||||||||||||||||
Alcohol/Food/Lifestyle Interactions |
|||||||||||||||||
|
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
|||||||||||||||||
Disease Interactions |
|||||||||||||||||
First Approval Date |
|||||||||||||||||
|
December 07, 1953 |
March 21, 2014 |
||||||||||||||||
WADA ClassView World Anti-Doping Agency classifications. |
|||||||||||||||||
|
N/A |
N/A |
||||||||||||||||
More Information |
|||||||||||||||||
Consumer Resources |
|||||||||||||||||
Professional Resources |
|||||||||||||||||
Related Treatment Guide |
|||||||||||||||||
|
|||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.