Comparing Cosentyx vs Methotrexate
Cosentyx Remove Cosentyx from your drug comparison | Methotrexate Remove Methotrexate from your drug comparison |
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Cosentyx secukinumab Remove Cosentyx from your drug comparison | Methotrexate Remove Methotrexate from your drug comparison | ||||||||||||||||
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Cosentyx may be used to treat plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and some other conditions. After an initial loading dose, Cosentyx needs to be injected subcutaneously... View more |
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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6.1
For Plaque Psoriasis: 50 year old Trial attorney with an exceptionally stressful job. Second year of law school, developed a few small spots. Lived with it for 20 plus years with only two large patches on both ankles of which I would cover up; one big spot on my left knee. While on vacation, severe case of strep throat. Started Penicillin, cleared my strep throat up and 4 days later, my ENTIRE body flared up. It was horrible. This NEVER happened, ever before and was clearly caused by strep throat. Began first (nothing else) Cosenytx 300 mg. Just finished my 2nd dosage and starting 3rd Tuesday. It has "SLOWLY" helped. Itching is gone. The red patches have definitely reduced in their inflammation. I feel positive but the jury is still out. I will give it more time and see what happens. Fortunately, insurance covered it after much fighting (and photographs of my body). First biologic ever as never needed it before. Some mild edema on both ankles but no "major" side effects as of yet. |
6.7
For Rheumatoid Arthritis: I had taken MTX in past but it did not work out for me due to rash proplem caused by MTX so Doctor recommended Sulfasalazine and it worked out very good for about 4 years but the end of friendship came to us...Sulfasalazine was not effective anymore. I met a Doctor who practice natrual madicine also ER Dortor at the local hospital....He recommended 3 natrual Supplements for RA and pain( Turmeric, Wobenzym N, White Willow) and they are very effective (on me) and it is better than Chemical based medications. I have been off from those deadly medications for 5 months now. For Rheumatoid Arthritis: I have been on 15mg then 20mg for two years. Then developed constant explosive diarrhea, dizziness, and confusion. Judged to be allergic, and told to stop the medication immediately. The symptoms continue...how long before it gets better? I am not taking anything for RA right now after a week off methotrexate. |
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Drug Class |
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Side Effects |
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Common side effects include: infection, and nasopharyngitis. See the full Cosentyx side effects document. |
Commonly reported side effects include: increased liver enzymes. See the full methotrexate side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Cosentyx prices |
View all methotrexate prices |
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Generic Availability |
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No |
Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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N/A |
Methotrexate LPF Sodium, Otrexup, Rasuvo, RediTrex, Trexall, Xatmep | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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744 hours |
12 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
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Drug Interactions |
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A total of 167 drugs are known to interact with Cosentyx:
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A total of 589 drugs are known to interact with methotrexate:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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January 21, 2015 |
December 07, 1953 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Plaque Psoriasis: Have been on Cosentyx for almost a year and wondering if anyone else may have experienced vision problems after taking this drug? I am 43 years old and had an “eye stroke” called BRVO in one eye, which is very uncommon for someone my age. I also have a lot of eye twitching. My ALT & AST enzymes have also been elevated while taking Cosentyx. Thank you in advance for your feedback.