Comparing Cosentyx vs Methotrexate
| Cosentyx | Methotrexate |
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| Cosentyx secukinumab | Methotrexate |
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Cosentyx may be used to treat plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and some other conditions. After an initial loading dose, Cosentyx needs to be injected subcutaneously... View more |
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
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| More about Cosentyx (secukinumab) | More about Methotrexate | ||||||||||||||||
| Generic Status | |||||||||||||||||
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No lower-cost generic available |
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| Availability | |||||||||||||||||
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Prescription only |
Prescription only |
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| Ratings & Reviews | |||||||||||||||||
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Cosentyx has an average rating of 6.1 out of 10 from a total of 196 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 36% reported a negative effect. |
Methotrexate has an average rating of 6.6 out of 10 from a total of 264 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 24% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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Common side effects include: infection, and nasopharyngitis. See the full Cosentyx side effects document. |
Commonly reported side effects include: increased liver enzymes. See the full methotrexate side effects document. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Cosentyx prices |
View all methotrexate prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Methotrexate LPF Sodium, Otrexup, Rasuvo, RediTrex, Trexall, Xatmep | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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744 hours |
15 hours |
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| CSA Schedule** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 189 drugs are known to interact with Cosentyx:
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A total of 627 drugs are known to interact with methotrexate:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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January 21, 2015 |
December 07, 1953 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.