Comparing Celebrex vs Methotrexate
| Celebrex Remove Celebrex from your drug comparison | Methotrexate Remove Methotrexate from your drug comparison |
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| Celebrex celecoxib Remove Celebrex from your drug comparison | Methotrexate Remove Methotrexate from your drug comparison |
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Celebrex is a COX-2 specific NSAID that has a lower propensity for gastrointestinal side effects than many other NSAIDs; however, it still may increase the risk of serious cardiovascular thrombotic... View more |
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
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Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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Common side effects include: diarrhea, hypertension, and abnormal hepatic function tests. See the full Celebrex side effects document. |
Commonly reported side effects include: increased liver enzymes. See the full methotrexate side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Celebrex prices and generic prices |
View all methotrexate prices |
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Generic Availability |
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Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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| Other celecoxib brands include: Elyxyb | Methotrexate LPF Sodium, Otrexup, Rasuvo, RediTrex, Trexall, Xatmep | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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11 hours |
12 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full Pregnancy Warnings document. |
Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
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Drug Interactions |
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A total of 360 drugs are known to interact with Celebrex:
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A total of 610 drugs are known to interact with methotrexate:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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December 31, 1998 |
December 07, 1953 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.