Comparing Celebrex vs Methotrexate
| Celebrex | Methotrexate |
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| Celebrex (celecoxib) | Methotrexate |
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Prescription only
Celebrex is a COX-2-specific NSAID that has a lower propensity for gastrointestinal side effects than many other NSAIDs; however, it still may increase the risk of serious cardiovascular thrombotic... View more |
Prescription only
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
Related suggestions Rheumatoid Arthritis
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| More about Celebrex (celecoxib) | More about Methotrexate | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Celebrex has an average rating of 7.1 out of 10 from a total of 223 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 22% reported a negative effect. |
Methotrexate has an average rating of 6.6 out of 10 from a total of 334 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 23% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: Celebrex side effects in more detail. |
See also: methotrexate side effects in more detail. |
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| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Celebrex prices |
View all methotrexate prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other celecoxib brands include: Elyxyb | Jylamvo, Methotrexate LPF Sodium, Otrexup, Rasuvo, Trexall, Xatmep | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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11 hours |
15 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 422 drugs are known to interact with Celebrex:
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A total of 694 drugs are known to interact with methotrexate:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 31, 1998 |
December 07, 1953 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.