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Medications for Period Pain (Dysmenorrhea)

Drugs associated with Period Pain

The following drugs and medications are in some way related to, or used in the treatment of this condition.

What is Period Pain: Difficult and painful menstruation.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
ibuprofen Rx/OTC C N X 10 reviews
8.0

Generic name: ibuprofen systemic

Brand names:  Advil, Advil Liqui-Gels, Motrin, IBU, Midol IB, Motrin IB, Ibu-8, Nuprin, A-G Profen, Actiprofen, Addaprin, Advil Children's, Genpril, Haltran, Ibu-4, Ibu-6, IBU-200, Ibu-Tab, Proprinal, Q-Profen

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
naproxen Rx/OTC C N X 45 reviews
8.0

Generic name: naproxen systemic

Brand names:  Aleve, Naprosyn, Anaprox, Anaprox-DS, Midol Extended Relief, Naprelan, EC-Naprosyn, Flanax Pain Reliever, Aflaxen, All Day Pain Relief, All Day Relief, Leader Naproxen Sodium

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Advil Rx/OTC C N X Add review
8.0

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Aleve Rx/OTC C N X 4 reviews
8.0

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
Ponstel Rx C N X 13 reviews
7.0

Generic name: mefenamic acid systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Cataflam Rx D N X 14 reviews
8.0

Generic name: diclofenac systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Voltaren Rx D N X 2 reviews
8.0

Generic name: diclofenac systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Naprosyn Rx/OTC C N X Add review
8.0

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Orudis Rx C N X Add review
10

Generic name: ketoprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
mefenamic acid Rx C N X 29 reviews
7.0

Generic name: mefenamic acid systemic

Brand name:  Ponstel

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Advil Liqui-Gels Rx/OTC C N X 2 reviews
9.0

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Celebrex Rx C N 1 review
4.0

Generic name: celecoxib systemic

Drug class: cox-2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
diclofenac Rx D N X 27 reviews
8.0

Generic name: diclofenac systemic

Brand names:  Cataflam, Voltaren, Voltaren-XR

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Motrin Rx/OTC C N X 2 reviews
7.0

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Anaprox Rx/OTC C N X Add review
7.0

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
Anaprox-DS Rx/OTC C N X 2 reviews
6.0

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
Midol Extended Relief Rx/OTC C N X 1 review
10

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
IBU Rx/OTC C N X Add review
8.0

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
ketoprofen Rx/OTC C N X Add review
10

Generic name: ketoprofen systemic

Brand names:  Orudis, Oruvail, Orudis KT

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Midol IB Rx/OTC C N X Add review Add

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
Naprelan Rx/OTC C N X 1 review
10

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Motrin IB Rx/OTC C N X 1 review
10

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Voltaren-XR Rx D N X Add review Add

Generic name: diclofenac systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Ansaid Rx C N X 1 review
8.0

Generic name: flurbiprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
celecoxib Rx C N 1 review
4.0

Generic name: celecoxib systemic

Brand name:  Celebrex

Drug class: cox-2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
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Alternative treatments for Period Pain

The following products are considered to be alternative treatments or natural remedies for Period Pain. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Period Pain.

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N The drug is not subject to the Controlled Substances Act.
1 The drug has a high potential for abuse. The drug has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use of the drug under medical supervision.
2 The drug has a high potential for abuse. The drug has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug may lead to severe psychological or physical dependence.
3 The drug has a potential for abuse less than the drugs in schedules 1 and 2. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to moderate or low physical dependence or high psychological dependence.
4 The drug has a low potential for abuse relative to the drugs in schedule 3. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 3.
5 The drug has a low potential for abuse relative to the drugs in schedule 4. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 4.
Alcohol
X Interacts with Alcohol.

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