Comparing Enbrel vs Otezla

For Rheumatoid Arthritis I've had RA for two years now. Started MTX about 7 months ago. I started to get worse, not able to open bedroom door in the morning. Stiffness lasting most of the morning and joint pain all day. MTX increased to max dosage without improvement. I take MTX injections. Started Embrel a month ago, much improved with first injection. Now morning I do not have a lot of stiffness, still have joint pain but it is improving as well. My RA was rated as severe. I've had no real side affects from either drug. I have muscle pain in my legs which I understand can be a side affect of Embrel but it beats the joint pain. I had read that the Embrel injections were painful. I personally did not find that to be true.

For Rheumatoid Arthritis I have severe RA and was started on MTX about 6 months ago already maxed out and pain and inflammation was doing major damage. Two years ago I was running a mile several times a week and when the RA hit I could not even open my bedroom door. Recently was started on Embrel. After the first shot I noticed a 25% improvement with pain and stiffness. I did not find the shot painful as some describe, but I had already been self injecting the MTX. No other side affects thus far. Looking forward to my second injection this week and continued improvement.

For Plaque Psoriasis I have tried otezla twice the first time it cause horrible stomach pain and I had to discontinue it after three weeks. It worked miracles for my skin though almost all clear. I went to GI to get something to counteract the otezla. Went back on it and after two months on it I started having really bad panic attacks. I am not a panic person and have never had anxiety it got so bad I had to stop the pills. However be warned you can not just stop the pills you have to slowly decrease the dose the same way you have to increase in the beginning. I was not told this and ended up in the ER.

For Plaque Psoriasis I've been on Otezla a little over a year now and I think I will be stopping tomorrow after I visit my dermatologist. The Pros, much of my psoriasis cleared within weeks, especially on my neck and scalp. When doing UV treatments with the Otezla I was near 95% clear. I had all the side effects like tension headaches, stomach issues, and weight loss. However, I would take that and clearer skin over my psoriasis. I've had psoriasis for 24 years now and I have tried everything from steroid creams, UV, and biologic injections. I thought Otezla was the best! However, over the last month I have been experiencing anxiety and depression. I get stressed out so easily and having panic attacks has never been me. I cannot function normally.