Comparing Enbrel vs Otezla

For Rheumatoid Arthritis I've had RA for two years now. Started MTX about 7 months ago. I started to get worse, not able to open bedroom door in the morning. Stiffness lasting most of the morning and joint pain all day. MTX increased to max dosage without improvement. I take MTX injections. Started Embrel a month ago, much improved with first injection. Now morning I do not have a lot of stiffness, still have joint pain but it is improving as well. My RA was rated as severe. I've had no real side affects from either drug. I have muscle pain in my legs which I understand can be a side affect of Embrel but it beats the joint pain. I had read that the Embrel injections were painful. I personally did not find that to be true.

For Rheumatoid Arthritis I have severe RA and was started on MTX about 6 months ago already maxed out and pain and inflammation was doing major damage. Two years ago I was running a mile several times a week and when the RA hit I could not even open my bedroom door. Recently was started on Embrel. After the first shot I noticed a 25% improvement with pain and stiffness. I did not find the shot painful as some describe, but I had already been self injecting the MTX. No other side affects thus far. Looking forward to my second injection this week and continued improvement.

For Plaque Psoriasis I have had psoriasis my entire life, the last 6 years, it has been so bad on my feet, walking is a problem. I have been on Otezla for about 3 weeks. Here is what I have experienced; I have had some good results on my feet, but a bit of a trade off. Loss of appetite, nausea occasionally, no headaches at all, and only one day of feeling lethargic and a bit sad. I also get itchy, sometimes my skin crawls especially at night, and yesterday my bones actually ached. It is so random when this comes and goes. I am still on the fence a bit with it. I am hoping these things will go away. I haven't heard anything about long term effects.

For Plaque Psoriasis I am heading into my 4th week with Otezla. My hands are clear of scales. They are looking very good. My scalp has stopped itching and feels like scales are disappearing. My legs on the other hand are red and itching. I do not see any improvement on my legs at all yet. I did experience severe nausea for the first couple of weeks but it has gotten much better. Slight occasional headaches. I am still hopeful.