Comparing Enbrel vs Otezla
| Enbrel Remove Enbrel from your drug comparison | Otezla Remove Otezla from your drug comparison |
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| Enbrel etanercept Remove Enbrel from your drug comparison | Otezla apremilast Remove Otezla from your drug comparison | ||||||||||||||||
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Enbrel is a subcutaneous injection that is usually self-administered once or twice a week for inflammatory conditions such as rheumatoid arthritis, psoriasis, psoriatic arthritis, or ankylosing... View more |
Otezla is a PDE4 inhibitor that may be used to treat plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet’s Disease. It has been associated with severe diarrhea, nausea, and v... View more |
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Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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Common side effects include: infection, and injection site reaction. See the full Enbrel side effects document. |
Common side effects include: weight loss. See the full Otezla side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Enbrel prices |
View all Otezla prices |
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Generic Availability |
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No |
No |
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Dosage Form(s) Available |
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Brand Names |
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| Other etanercept brands include: Erelzi, Eticovo |
N/A |
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Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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300 hours |
9 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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Drug Interactions |
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A total of 401 drugs are known to interact with Enbrel:
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A total of 71 drugs are known to interact with Otezla:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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November 02, 1998 |
March 21, 2014 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.