Comparing Enbrel vs Humira

For Rheumatoid Arthritis I've had RA for two years now. Started MTX about 7 months ago. I started to get worse, not able to open bedroom door in the morning. Stiffness lasting most of the morning and joint pain all day. MTX increased to max dosage without improvement. I take MTX injections. Started Embrel a month ago, much improved with first injection. Now morning I do not have a lot of stiffness, still have joint pain but it is improving as well. My RA was rated as severe. I've had no real side affects from either drug. I have muscle pain in my legs which I understand can be a side affect of Embrel but it beats the joint pain. I had read that the Embrel injections were painful. I personally did not find that to be true.

For Rheumatoid Arthritis I have severe RA and was started on MTX about 6 months ago already maxed out and pain and inflammation was doing major damage. Two years ago I was running a mile several times a week and when the RA hit I could not even open my bedroom door. Recently was started on Embrel. After the first shot I noticed a 25% improvement with pain and stiffness. I did not find the shot painful as some describe, but I had already been self injecting the MTX. No other side affects thus far. Looking forward to my second injection this week and continued improvement.

For Rheumatoid Arthritis I'm a 69 yr old woman with seronegative RA - hence it took a long time for a diagnosis. Many rheumatologists do not understand that you can be seronegative & have RA. Sad. After several years of anti inflammatory drugs & cortisone I was prescribed Humira. Took about 2 months & wow! Not so much pain relief but having so much less fatigue. As I live in Australia my experience with obtaining the drug is different to the US. My rheumatologist makes application through the federal government after other drugs have failed & they heavily subsidise. Thus far no obvious side effects. However, reading other's comments I wonder about the flushes at night - never had them as a menopausal symptom...... Wish you all the best in managing RA

For Rheumatoid Arthritis I think the shots are very painful, they sting, no matter how you inject it. Let it sit out for 20 minutes first, etc. Also- I liked the injectable pen better when I was using Enbrel. This needle is a real needle, no injectable pen. I feel it's harder to use on yourself that way.