Comparing Accutane vs Spironolactone
Accutane | Spironolactone |
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Accutane (isotretinoin) | Spironolactone |
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Prescription only
Prescribed for Rosacea, Acne, Acute Nonlymphocytic Leukemia, Granuloma Annulare. Accutane may also be used for purposes not listed in this medication guide. |
Prescription only
Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. It does not cause potassium loss from the body; however... View more |
Related suggestions |
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More about Accutane (isotretinoin) | More about Spironolactone | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Accutane has an average rating of 8.0 out of 10 from a total of 655 ratings on Drugs.com. 74% of reviewers reported a positive effect, while 14% reported a negative effect. |
Spironolactone has an average rating of 6.9 out of 10 from a total of 696 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 24% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Accutane side effects in more detail. |
See also: spironolactone side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic approved |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Accutane prices |
View all spironolactone prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Other isotretinoin brands include: Absorica, Absorica LD, Amnesteem, Claravis, Myorisan, Sotret, Zenatane | Aldactone, CaroSpir | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
32 hours |
37 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 133 drugs are known to interact with Accutane:
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A total of 383 drugs are known to interact with spironolactone:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
May 07, 1982 |
January 21, 1960 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.