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Absorica

Generic Name: isotretinoin (oral) (EYE so TRET i noyn)
Brand Name: Absorica, Amnesteem, Claravis, Myorisan, Sotret, Zenatane

Medically reviewed on June 11, 2018

What is Absorica?

Absorica is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly.

Absorica is used to treat severe nodular acne that has not responded to other treatments, including antibiotics.

Absorica is available only from a certified pharmacy under a special program called iPLEDGE.

Absorica may also be used for purposes not listed in this medication guide.

Important Information

Absorica in just a single dose can cause severe birth defects or death of a baby. Never use Absorica if you are pregnant or may become pregnant.

You must have a negative pregnancy test before taking Absorica. You will also be required to use two forms of birth control to prevent pregnancy while taking this medicine. Stop using this medicine and call your doctor at once if you think you might be pregnant.

Before taking this medicine

Absorica can cause miscarriage, premature birth, severe birth defects, or death of a baby if the mother takes this medicine at the time of conception or during pregnancy. Even one dose of isotretinoin can cause major birth defects of the baby's ears, eyes, face, skull, heart, and brain. Never use this medicine if you are pregnant.

For Women: Unless you have had your uterus and ovaries removed (total hysterectomy) or have been in menopause for at least 12 months in a row, you are considered to be of child-bearing potential. You must have a negative pregnancy test before you start taking Absorica, before each prescription is refilled, right after you take your last dose of isotretinoin, and again 30 days later. All pregnancy testing is required by the iPLEDGE program.

You must agree in writing to use two specific forms of birth control beginning 30 days before you start taking Absorica and ending 30 days after your last dose. Both a primary and a secondary form of birth control must be used together.

Primary forms of birth control include:

  • tubal ligation (tubes tied);

  • vasectomy of the male sexual partner;

  • an IUD (intrauterine device);

  • estrogen-containing birth control pills (not mini-pills); and

  • hormonal birth control patches, implants, injections, or vaginal ring.

Secondary forms of birth control include:

  • a male latex condom with or without spermicide;

  • a diaphragm plus a spermicide;

  • a cervical cap plus a spermicide; and

  • a vaginal sponge containing a spermicide.

Not having sexual intercourse (abstinence) is the most effective method of preventing pregnancy.

Stop using Absorica and call your doctor at once if you have unprotected sex, if you quit using birth control, if your period is late, or if you think you might be pregnant. If you get pregnant while taking this medicine, call the iPLEDGE pregnancy registry at 1-866-495-0654.

You should not use Absorica if you are allergic to it.

Tell your doctor if you have ever had:

It is dangerous to try and purchase Absorica on the Internet or from vendors outside of the United States. The sale and distribution of isotretinoin outside of the iPLEDGE program violates the regulations of the U.S. Food and Drug Administration for the safe use of this medication.

You should not breast-feed while using this medicine.

Absorica is not approved for use by anyone younger than 12 years old.

How should I take Absorica?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Each prescription of isotretinoin must be filled within 7 days of the date it was written by your doctor. You will receive no more than a 30-day supply of isotretinoin at one time.

Always take Absorica with a full glass of water. Do not chew or suck on the capsule. Swallow it whole.

Follow all directions about taking Absorica with or without food.

Use Absorica for the full prescribed length of time. Your acne may seem to get worse at first, but should then begin to improve.

You may need frequent blood tests.

Never share this medicine with another person, even if they have the same symptoms you have.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include headache, dizziness, vomiting, stomach pain, warmth or tingling in your face, swollen or cracked lips, and loss of balance or coordination.

What should I avoid while taking Absorica?

Do not take a vitamin or mineral supplement that contains vitamin A.

Do not donate blood while taking Absorica and for at least 30 days after you stop taking it. Donated blood that is later given to a pregnant woman could lead to birth defects in her baby if the blood contains any level of isotretinoin.

While you are taking Absorica and for at least 6 months after your last dose: Do not use wax hair removers or have dermabrasion or laser skin treatments. Scarring may result.

Absorica could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Avoid driving or hazardous activity until you know how Absorica will affect you. Absorica may impair your vision, especially at night.

Absorica side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Stop using Absorica and call your doctor at once if you have:

  • problems with your vision or hearing;

  • hallucinations, (see or hearing things that are not real), thoughts about suicide or hurting yourself;

  • depressed mood, crying spells, changes in behavior, feeling angry or irritable;

  • loss of interest in things you enjoyed before, feeling hopeless or guilty;

  • sleep problems, extreme tiredness, trouble concentrating;

  • changes in weight or appetite;

  • a seizure (convulsions), sudden numbness or weakness;

  • muscle weakness, pain in your bones or joints or in your back;

  • severe diarrhea, rectal bleeding, bloody or tarry stools;

  • pale skin, feeling light-headed or short of breath;

  • severe stomach or chest pain, pain when swallowing; or

  • dark urine, or jaundice (yellowing of your skin or eyes).

Common side effects may include:

  • dryness of your skin, lips, eyes, or nose (you may have nosebleeds).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Absorica?

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may affect Absorica, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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